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Mechanisms Underlying Visceral Hypersensitivity in Irritable Bowel Syndrome [PDF]
Current Gastroenterology Reports, 2011 Visceral hypersensitivity is currently considered a key pathophysiological mechanism involved in pain perception in large subgroups of patients with functional gastrointestinal disorders, including irritable bowel syndrome (IBS). In IBS, visceral hypersensitivity has been described in 20%-90% of patients.
Giovanni Barbara +2 more
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Visceral Hypersensitivity Is Not a Feature of Fibromyalgia Syndrome [PDF]
Journal of Musculoskeletal Pain, 2001 Objective: Visceral hyperalgesia is commonly observed in irritable bowel syndrome [IBS], a common cause of comorbidity with fibromyalgia syndrome [FMS]. The aim of this study was to evaluate in patients affected by FMS the presence of IBS-like symptoms and of visceral hyperalgesia.Methods: Twenty-seven FMS patients were studied and compared with 32 IBS
F. Pace +6 more
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Serotonergic and non‐serotonergic targets in the pharmacotherapy of visceral hypersensitivity [PDF]
Neurogastroenterology & Motility, 2007 Abstract Visceral hypersensitivity is considered a key mechanism in the pathogenesis of functional gastrointestinal (GI) disorders. Targeting visceral hypersensitivity seems an attractive approach to the development of drugs for functional GI disorders. This review summarizes current knowledge on targets for the treatment of visceral hypersensitivity,
BUENO L. +8 more
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Visceral hypersensitivity in functional disorders of the upper gastrointestinal tract [PDF]
Digestive and Liver Disease, 2004 Visceral hypersensitivity is now recognised as a major pathophysiological mechanism in functional gastrointestinal disorders of the upper gastrointestinal tract. In patients with non-cardiac chest pain and functional dyspepsia, a high prevalence of visceral hypersensitivity has been indeed observed.
G, Sarnelli, J, Vandenberghe, J, Tack
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Markers for visceral hypersensitivity in patients with irritable bowel syndrome [PDF]
Neurogastroenterology and Motility, 2014 Background Irritable bowel syndrome (IBS) is a heterogenous disorder with visceral hypersensitivity as important hallmark. It is not known whether IBS patients with visceral hypersensitivity have different epidemiological and clinical characteristics ...
S Ludidi, Zlatan Mujagic, D Jonkers
exaly +2 more sources
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The interaction between obesity and visceral hypersensitivity
Journal of Gastroenterology and Hepatology, 2022AbstractObesity has been a worldwide problem associated with numerous chronic diseases such as cardiovascular disease, type 2 diabetes, and metabolic disorders. It may also play a role in visceral hypersensitivity, contributing to irritable bowel syndrome.
Wu Yanping +11 more
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Nihon rinsho. Japanese journal of clinical medicine, 2006
Colorectal hyperalgesia has been supposed to be one of the key pathophysiological roles in irritable bowel syndrome (IBS). Recent animal models have demonstrated that neonatal maternal deprivation (stress memory) or repetitive rectal distension (pain memory) in neonatal animal triggers long-term hypersensitivity to rectal distension, indicating that ...
Hiroshi, Kaneko +2 more
openaire +3 more sources
Colorectal hyperalgesia has been supposed to be one of the key pathophysiological roles in irritable bowel syndrome (IBS). Recent animal models have demonstrated that neonatal maternal deprivation (stress memory) or repetitive rectal distension (pain memory) in neonatal animal triggers long-term hypersensitivity to rectal distension, indicating that ...
Hiroshi, Kaneko +2 more
openaire +3 more sources
Journal of Clinical Gastroenterology, 2005
Visceral hypersensitivity is considered one of the causes of functional gastrointestinal disorders. The objectives of this review are to provide a practical description of neuroanatomy and physiology of gut sensation, to describe the diverse tests of visceral sensation and the potential role of brain imaging to further our understanding of visceral ...
Silvia, Delgado-Aros, Michael, Camilleri
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Visceral hypersensitivity is considered one of the causes of functional gastrointestinal disorders. The objectives of this review are to provide a practical description of neuroanatomy and physiology of gut sensation, to describe the diverse tests of visceral sensation and the potential role of brain imaging to further our understanding of visceral ...
Silvia, Delgado-Aros, Michael, Camilleri
openaire +2 more sources
Biomarkers for visceral hypersensitivity in patients with irritable bowel syndrome [PDF]
Neurogastroenterology and Motility, 2017 Background Increased visceral sensitivity is observed in up to 60% of patients with Irritable Bowel Syndrome (IBS). Mucosal inflammation, altered neuroendocrine activity and intraluminal metabolic processes may contribute to the development of visceral ...
Zlatan Mujagic +2 more
exaly +3 more sources
Role of enteric glia in mechanisms of visceral hypersensitivity [PDF]
, 2023 Abdominal pain is the most common gastrointestinal (GI) issue and the most debilitating feature of disorders of gut-brain interaction (DGBI) such as irritable bowel syndrome (IBS) and the inflammatory bowel diseases (IBDs).
Morales-Soto, Wilmarie
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