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Mechanisms Underlying Visceral Hypersensitivity in Irritable Bowel Syndrome
Current Gastroenterology Reports, 2011 Visceral hypersensitivity is currently considered a key pathophysiological mechanism involved in pain perception in large subgroups of patients with functional gastrointestinal disorders, including irritable bowel syndrome (IBS). In IBS, visceral hypersensitivity has been described in 20%-90% of patients.
Giovanni Barbara +2 more
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The interaction between obesity and visceral hypersensitivity
Journal of Gastroenterology and Hepatology, 2022AbstractObesity has been a worldwide problem associated with numerous chronic diseases such as cardiovascular disease, type 2 diabetes, and metabolic disorders. It may also play a role in visceral hypersensitivity, contributing to irritable bowel syndrome.
Wu Yanping +11 more
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Nihon rinsho. Japanese journal of clinical medicine, 2006
Colorectal hyperalgesia has been supposed to be one of the key pathophysiological roles in irritable bowel syndrome (IBS). Recent animal models have demonstrated that neonatal maternal deprivation (stress memory) or repetitive rectal distension (pain memory) in neonatal animal triggers long-term hypersensitivity to rectal distension, indicating that ...
Hiroshi, Kaneko +2 more
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Colorectal hyperalgesia has been supposed to be one of the key pathophysiological roles in irritable bowel syndrome (IBS). Recent animal models have demonstrated that neonatal maternal deprivation (stress memory) or repetitive rectal distension (pain memory) in neonatal animal triggers long-term hypersensitivity to rectal distension, indicating that ...
Hiroshi, Kaneko +2 more
openaire +3 more sources
Journal of Clinical Gastroenterology, 2005
Visceral hypersensitivity is considered one of the causes of functional gastrointestinal disorders. The objectives of this review are to provide a practical description of neuroanatomy and physiology of gut sensation, to describe the diverse tests of visceral sensation and the potential role of brain imaging to further our understanding of visceral ...
Silvia, Delgado-Aros, Michael, Camilleri
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Visceral hypersensitivity is considered one of the causes of functional gastrointestinal disorders. The objectives of this review are to provide a practical description of neuroanatomy and physiology of gut sensation, to describe the diverse tests of visceral sensation and the potential role of brain imaging to further our understanding of visceral ...
Silvia, Delgado-Aros, Michael, Camilleri
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Anorectal Function and Visceral Hypersensitivity in Celiac Disease
Journal of Clinical Gastroenterology, 2010To evaluate anorectal function and rectal sensitivity thresholds in patients with celiac disease (CD).In 25 unselected patients with CD (16 female, 9 male; mean age 45, range 24 to 75 y) and 20 controls (12 female, 8 male; mean age 41, range 20 to 65 y) anorectal manometry and rectal balloon distension test were conducted using a 4 lumen water perfused
Agata Mulak +2 more
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Alimentary Pharmacology & Therapeutics, 2003
SummaryVisceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut.
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SummaryVisceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut.
openaire +1 more source
Evidence for visceral hypersensitivity in high-anxiety rats
Physiology & Behavior, 2000In patients with irritable bowel syndrome, anxiety is often associated with visceral pain. Based on this information we hypothesized that rats genetically predisposed to anxiety have an increased visceral sensitivity. To test this hypothesis, visceromotor reflex recordings in response to colorectal distention were used to estimate the level of visceral
W D, Gunter +4 more
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Visceral hypersensitivity in noncardiac chest pain
Gastroenterology Clinics of North America, 2004Visceral hypersensitivity is a common cause of NCCP. Mechanoreceptors appear to be important in the pathophysiology of NCCP, although chemoreceptors also appear to play a significant role. The processing of visceral information and possibly the development of central sensitization may be important in NCCP, although the pathophysiology of NCCPremains ...
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2018
Visceral hypersensitivity is an important mechanism in the development of functional gastrointestinal disorders (FGID), including irritable bowel syndrome (IBS), noncardiac disorder, and functional dyspepsia (FD). In pathophysiology of FD, visceral hypersensitivity in gastric distension is a main mechanism in addition to gastric motor dysfunction ...
Yasuhito Uezono, Kanako Miyano
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Visceral hypersensitivity is an important mechanism in the development of functional gastrointestinal disorders (FGID), including irritable bowel syndrome (IBS), noncardiac disorder, and functional dyspepsia (FD). In pathophysiology of FD, visceral hypersensitivity in gastric distension is a main mechanism in addition to gastric motor dysfunction ...
Yasuhito Uezono, Kanako Miyano
exaly +2 more sources
Visceral hypersensitivity in non-erosive reflux disease
Gut, 2007Non-erosive reflux disease (NERD) is defined as the presence of classic symptoms of gastro-oesophageal reflux disease (GORD) in the absence of oesophageal mucosal injury (or Barrett’s oesophagus) as determined by inspection at upper gastrointestinal endoscopy.1 As such it is regarded as being one of the two main phenotypes of GORD, the other being ...
C H, Knowles, Q, Aziz
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