Visceral hypersensitivity - Open Access .click

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P2X receptor-mediated visceral hyperalgesia in a rat model of chronic visceral hypersensitivity

Gut, 2008
Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterised by abdominal pain and bloating in association with altered bowel movements. Its pathogenesis and the underlying molecular mechanisms of visceral hyperalgesia remain elusive. Recent studies of somatic and other visceral
G-Y, Xu +4 more
openaire +2 more sources

Review article: visceral hypersensitivity.

Alimentary pharmacology & therapeutics, 2003
Visceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut.
openaire +1 more source

Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity

Neuron, 2023
Zili Xie, Bao Nan Chen, Hongzhen Hu
exaly

Parental Care, Mast Cells and Visceral Hypersensitivity