Results 191 to 200 of about 343,535 (222)
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The interaction between obesity and visceral hypersensitivity
Journal of Gastroenterology and Hepatology, 2022Obesity has been a worldwide problem associated with numerous chronic diseases such as cardiovascular disease, type 2 diabetes, and metabolic disorders. It may also play a role in visceral hypersensitivity, contributing to irritable bowel syndrome.
Wu Yanping +11 more
semanticscholar +3 more sources
Brain, behavior, and immunity, 2023
Inflammatory bowel disease (IBD) is a chronic condition with a high recurrence rate. To date, the clinical treatment of IBD mainly focuses on inflammation and gastrointestinal symptoms while ignoring the accompanying visceral pain, anxiety, depression ...
Ke Wu +6 more
semanticscholar +1 more source
Inflammatory bowel disease (IBD) is a chronic condition with a high recurrence rate. To date, the clinical treatment of IBD mainly focuses on inflammation and gastrointestinal symptoms while ignoring the accompanying visceral pain, anxiety, depression ...
Ke Wu +6 more
semanticscholar +1 more source
Nihon rinsho. Japanese journal of clinical medicine, 2006
Colorectal hyperalgesia has been supposed to be one of the key pathophysiological roles in irritable bowel syndrome (IBS). Recent animal models have demonstrated that neonatal maternal deprivation (stress memory) or repetitive rectal distension (pain memory) in neonatal animal triggers long-term hypersensitivity to rectal distension, indicating that ...
Hiroshi, Kaneko +2 more
openaire +3 more sources
Colorectal hyperalgesia has been supposed to be one of the key pathophysiological roles in irritable bowel syndrome (IBS). Recent animal models have demonstrated that neonatal maternal deprivation (stress memory) or repetitive rectal distension (pain memory) in neonatal animal triggers long-term hypersensitivity to rectal distension, indicating that ...
Hiroshi, Kaneko +2 more
openaire +3 more sources
Neuropeptides, 2022
Growing evidence indicates that visceral hypersensitivity and impaired gut barrier play an important role in the pathophysiology of irritable bowel syndrome (IBS).
T. Nozu +4 more
semanticscholar +1 more source
Growing evidence indicates that visceral hypersensitivity and impaired gut barrier play an important role in the pathophysiology of irritable bowel syndrome (IBS).
T. Nozu +4 more
semanticscholar +1 more source
Journal of Clinical Gastroenterology, 2005
Visceral hypersensitivity is considered one of the causes of functional gastrointestinal disorders. The objectives of this review are to provide a practical description of neuroanatomy and physiology of gut sensation, to describe the diverse tests of visceral sensation and the potential role of brain imaging to further our understanding of visceral ...
Silvia, Delgado-Aros, Michael, Camilleri
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Visceral hypersensitivity is considered one of the causes of functional gastrointestinal disorders. The objectives of this review are to provide a practical description of neuroanatomy and physiology of gut sensation, to describe the diverse tests of visceral sensation and the potential role of brain imaging to further our understanding of visceral ...
Silvia, Delgado-Aros, Michael, Camilleri
openaire +2 more sources
Neurogastroenterology and Motility, 2021
Destruction of the intestinal mucosal barrier and visceral hypersensitivity are main pathogenesis of irritable bowel syndrome (IBS). The study aimed to establish a rat model of visceral hypersensitivity and explore mechanisms involved the changes of the ...
Li Zhao +10 more
semanticscholar +1 more source
Destruction of the intestinal mucosal barrier and visceral hypersensitivity are main pathogenesis of irritable bowel syndrome (IBS). The study aimed to establish a rat model of visceral hypersensitivity and explore mechanisms involved the changes of the ...
Li Zhao +10 more
semanticscholar +1 more source
Behavioural Brain Research, 2021
Early-life stress (ELS) is a high-risk factor for the development of chronic visceral pain in adulthood. Emerging evidence suggests that mast cells play a key role in the development of visceral hypersensitivity through interaction with neurons.
Ziyang Chen +4 more
semanticscholar +1 more source
Early-life stress (ELS) is a high-risk factor for the development of chronic visceral pain in adulthood. Emerging evidence suggests that mast cells play a key role in the development of visceral hypersensitivity through interaction with neurons.
Ziyang Chen +4 more
semanticscholar +1 more source
Alimentary Pharmacology & Therapeutics, 2003
SummaryVisceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut.
openaire +1 more source
SummaryVisceral hypersensitivity is highly prevalent in all functional bowel disorders. Most also demonstrate wider patterns of somatic referral of intestinal pain or discomfort. This hypersensitivity may explain the symptoms as the sensitive gut can be more easily provoked by normal or abnormal motor events in the gut.
openaire +1 more source
Visceral hypersensitivity in non-erosive reflux disease
Gut, 2007Non-erosive reflux disease (NERD) is defined as the presence of classic symptoms of gastro-oesophageal reflux disease (GORD) in the absence of oesophageal mucosal injury (or Barrett’s oesophagus) as determined by inspection at upper gastrointestinal endoscopy.1 As such it is regarded as being one of the two main phenotypes of GORD, the other being ...
C H, Knowles, Q, Aziz
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Visceral hypersensitivity in noncardiac chest pain
Gastroenterology Clinics of North America, 2004Visceral hypersensitivity is a common cause of NCCP. Mechanoreceptors appear to be important in the pathophysiology of NCCP, although chemoreceptors also appear to play a significant role. The processing of visceral information and possibly the development of central sensitization may be important in NCCP, although the pathophysiology of NCCPremains ...
openaire +2 more sources