Results 71 to 80 of about 195,947 (275)

Laboratory confirmed miltefosine resistant cases of visceral leishmaniasis from India

Parasites & Vectors, 2017
BackgroundMiltefosine unresponsive and relapse cases of visceral leishmaniasis (VL) are increasingly being reported. However, there has been no laboratory confirmed reports of miltefosine resistance in VL.
Saumya S. Srivastava, Jyotsna K. Mishra, A. Gupta, Amit Singh, P. Shankar, Sarman Singh   +5 more
semanticscholar   +1 more source

Unravelling the biochemical aspects of the interaction between ticks and Leishmania using a tick cell line

Medical and Veterinary Entomology, EarlyView.
Leishmania infantum propagated in IDE8 tick cell line in vitro. L. infantum reduces tick cell viability and induces reactive oxygen species production. Lipidic profile of IDE8 tick cell line is altered during Leishmania infection. Abstract Leishmaniasis comprises a group of vector‐borne neglected tropical diseases caused by species of the obligatory ...
Beatriz Filgueiras Silvestre, Karoline dos Anjos Lima, Fernanda de Paula Pepino, Daniela Cosentino‐Gomes, Adivaldo Fonseca, Lesley Bell‐Sakyi, Georgia Correa Atella, Lucia H. Pinto‐da‐Silva   +7 more
wiley   +1 more source

Epidemiology of visceral leishmaniasis [PDF]

Clinical Epidemiology, 2014
Leishmania species are the causative agents of leishmaniasis, a neglected tropical disease. These parasitic protozoans are usually transmitted between vertebrate hosts by the bite of blood sucking female phlebotomine sand flies. This review focuses on the two parasites causing most human visceral leishmaniasis (VL), which leads to substantial health ...
openaire   +4 more sources

Developing giant plasma membrane vesicles from Leishmania cells to investigate the role of membrane proteins in photodynamic inactivation

Photochemistry and Photobiology, EarlyView.
In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza, Pietro Ciancaglini, Rosangela Itri, Martha S. Ribeiro   +3 more
wiley   +1 more source

A case report on para-kala-azar dermal leishmaniasis: an unresolved mystery

BMC Infectious Diseases, 2023
Background Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that occurs 2–3 years after an apparently successful treatment of visceral leishmaniasis (VL).
Md. Mehedi Hasan, Sanghita Banik Proma, Md. Saddam Hossain, Md. Arifuzzaman, Naylla Islam, Md. Abu Bakar Siddique, Amiruzzaman   +6 more
doaj   +1 more source

Assessment of Leishmania exposure in blood donors from a non‐endemic urban area: A study in São Paulo

Vox Sanguinis, EarlyView.
Abstract Background and Objectives According to the World Health Organization, more than 1 billion people are at risk of leishmaniasis in over 89 countries. Environmental changes such as deforestation, urban expansion and climate change facilitate the spread of sand fly vectors and reservoirs, increasing disease transmission.
Ismael Severino de Lima, Suzete Cleusa Ferreira, Anna Shoko Nishiya, Norival Kesper Jr., Jerenice Esdras Ferreira, Claudia Maria de Castro Gomes, Juliana Derriga, Katia Cristina Dantas, Silvia Petrossi Gallo Polato, Nanci Alves Salles, Jose Angelo Lauletta Lindoso, Tila Fanciani, Cesar de Almeida‐Neto, Vanderson Rocha, Alfredo Mendrone Jr.   +14 more
wiley   +1 more source

Leishmaniasis–HIV coinfection: current challenges

HIV/AIDS: Research and Palliative Care, 2016
José Angelo Lauletta Lindoso,1,2 Mirella Alves Cunha,3 Igor Thiago Queiroz,4 Carlos Henrique Valente Moreira2 1Laboratory of Soroepidemiology (LIM HC-FMUSP), São Paulo University, São Paulo, 2Instituto de Infectologia Emilio ...
Lindoso JAL, Cunha MA, Queiroz IT, Moreira CHV   +3 more
doaj  

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

eLife, 2016
Leishmania donovani causes visceral leishmaniasis (VL), the second most deadly vector-borne parasitic disease. A recent epidemic in the Indian subcontinent (ISC) caused up to 80% of global VL and over 30,000 deaths per year. Resistance against antimonial
H. Imamura, Tim Downing, F. Van den Broeck, M. Sanders, S. Rijal, S. Sundar, An Mannaert, M. Vanaerschot, M. Berg, G. De Muylder, F. Dumetz, Bart Cuypers, I. Maes, M. Domagalska, Saskia Decuypere, K. Rai, S. Uranw, N. Bhattarai, B. Khanal, V. Prajapati, Smriti Sharma, Olivia Stark, G. Schönian, H. D. de Koning, L. Settimo, Benoît Vanhollebeke, Syamal Roy, B. Ostyn, M. Boelaert, L. Maes, M. Berriman, J. Dujardin, J. Cotton   +32 more
semanticscholar   +1 more source

New Se‐Compounds With Antileishmanial, Antitumor, and Carbonic Anhydrase Inhibitory Properties

Archiv der Pharmazie, Volume 358, Issue 12, December 2025.
A small library of selenocompounds was evaluated for their antileishmanial, antitumoral, and human carbonic anhydrase (hCA) inhibitory properties. Two trifluoromethoxy‐substituted anilide derivatives (3 and 6) were the most effective ones against Leishmania major (L. major) and Leishmania infantum (L. infantum) promastigotes and also showed a promising
Cristina Morán‐Serradilla, Daniel Plano, Andrea Angelli, Arun K. Sharma, Carmen Sanmartin, Claudiu T. Supuran   +5 more
wiley   +1 more source

Current challenges in treatment options for visceral leishmaniasis in India: a public health perspective

Infectious Diseases of Poverty, 2016
Visceral leishmaniasis (VL) is a serious parasitic disease causing considerable mortality and major disability in the Indian subcontinent. It is most neglected tropical disease, particularly in terms of new drug development for the lack of financial ...
O. Singh, Bhawana Singh, J. Chakravarty, S. Sundar   +3 more
semanticscholar   +1 more source