Results 81 to 90 of about 195,947 (275)
Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues +6 more
wiley +1 more source
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain +7 more
doaj +1 more source
Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer +6 more
wiley +1 more source
Modular nanosensing platforms utilize nanomaterials and functionalized interfaces to amplify trace different pathogens (like tuberculosis) antigen capture, suppress matrix interference, and enable multiplex detection. Their portability and cost‐effectiveness support rapid screening in resource‐limited settings and real‐time monitoring, advancing high ...
Mei Li +6 more
wiley +1 more source
Leishmaniasis is a highly diverse group of diseases caused by kinetoplastid of the genus Leishmania. These parasites are taxonomically diverse, with human pathogenic species separated into two subgenera according to their development site inside the ...
H. Valdivia +10 more
semanticscholar +1 more source
The State of Public Health in Somalia: Top 5 Challenges and Strategies for Improvement
Somalia's public health system is severely strained by five interconnected challenges: inadequate WASH infrastructure, widespread malnutrition and food insecurity, high burden of infectious diseases, critical gaps in maternal and child health, and the rising prevalence of noncommunicable diseases (NCDs).
Yusuf Hared Abdi +4 more
wiley +1 more source
Skin parasite landscape determines host infectiousness in visceral leishmaniasis
Increasing evidence suggests that the infectiousness of patients for the sand fly vector of visceral leishmaniasis is linked to parasites found in the skin.
J. Doehl +10 more
semanticscholar +1 more source
A novel salicylate‐based 1,2,3‐triazole salt was synthesized and demonstrated potent and selective activity against Leishmania amazonensis. The most active compound induced mitochondrial dysfunction without hemolytic effects. In silico analyses also suggested favorable pharmacokinetic properties and oral bioavailability.
Bruno A. De Oliveira +8 more
wiley +1 more source
Laboratory diagnosis of human visceral leishmaniasis.
Visceral leishmaniasis (VL), caused by the Leishmania donovani complex, is a vector-borne systemic disease, with a worldwide distribution causing high morbidity and mortality in the developing world.
H. Sakkas, C. Gartzonika, S. Levidiotou
semanticscholar +1 more source

