Neuroimmune Pain and Its Manipulation by Pathogens
ABSTRACT Recent studies highlight extensive crosstalk that exists between sensory neurons responsible for pain and the immune system. Cutaneous pain neurons detect harmful microbes, recruit immune cells, and produce anticipatory immunity in nearby tissues. These complementary systems generally protect hosts from infections.
Kevin W. Lozo+2 more
wiley +1 more source
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain+7 more
doaj +1 more source
Automatic quantification of abdominal subcutaneous and visceral adipose tissue in children, through MRI study, using total intensity maps and Convolutional Neural Networks [PDF]
Childhood overweight and obesity is one of the main health problems in the world since it is related to the early appearance of different diseases, in addition to being a risk factor for later developing obesity in adulthood with its health and economic consequences.
arxiv
The recombinant cysteine proteinase B (CPB) from Leishmania braziliensis and its domains: promising antigens for serodiagnosis of cutaneous and visceral leishmaniasis in dogs. [PDF]
Leishmaniasis represents a group of parasitic diseases caused by a protozoan of the genus Leishmania and is widely distributed in tropical and subtropical regions.
Basombrío, Manuel Alberto+10 more
core +1 more source
A case of visceral leishmaniasis mimicking connective tissue disease
Rheumatology &Autoimmunity, EarlyView.
Yucui Li+4 more
wiley +1 more source
Traditionally, adipocytes have been viewed as energy storage units, which upregulate inflammatory factors in response to obesity. However, emerging evidence demonstrates that adipocytes are highly responsive to systemic infection, and upregulate cytokines and antimicrobial compounds in response.
Matthew C. Sinton, Shingo Kajimura
wiley +1 more source
Direct-acting antivirals and visceral leishmaniasis: A case report [PDF]
Background: Visceral leishmaniasis is a vector-borne parasitic disease caused by protozoa belonging to the genus Leishmania. The clinical presentation of visceral leishmaniasis strictly depends on the host immunocompetency, whereas depressive conditions ...
Cascio, A.+7 more
core +1 more source
Therapeutic Options for Visceral Leishmaniasis [PDF]
Visceral leishmaniasis (VL), also known as Kala-Azar, is a disseminated protozoal infection caused principally by Leishmania donovani and Leishmania infantum (known as Leishmania chagasi in South America). The therapeutic options for VL are diverse and depend on different factors, such as the geographical area of the infection, development of ...
Begoña Monge-Maillo+1 more
openaire +3 more sources
Prolonged Fever in Children: An Inpatient Diagnostic Framework for Infections in Australia
ABSTRACT There are many causes of fever in children, ranging from common and self‐limiting to serious and life threatening. Careful assessment of children with prolonged fever without an obvious or identified source requires detailed history and examination with consideration of infections unique to the specific geographical region and individual ...
Heshani Rupasinghe+3 more
wiley +1 more source
Structures, targets and recent approaches in anti-leishmanial drug discovery and development. [PDF]
Recent years have seen a significant improvement in available treatment options for leishmaniasis. Two new drugs, miltefosine and paromomycin, have been registered for the treatment of visceral leishmaniasis (VL) in India since 2002.
Seifert, Karin
core +2 more sources