Results 81 to 90 of about 195,947 (275)

Oxidative Stress Modulation and Antileishmanial Activity of Salvinia auriculata

open access: yesChemistry &Biodiversity, Volume 22, Issue 12, December 2025.
Ethanolic extract of Salvinia auriculata showed significant antioxidant and antileishmanial activities. Salviniside II, the major metabolite, was isolated, structurally characterized, and evaluated, but exhibited weaker antiparasitic effects when compared to the whole extract.
Augusto César Rodrigues   +6 more
wiley   +1 more source

Amphotericin B deoxycholate for relapse visceral leishmaniasis in Bangladesh: a cross-sectional study

open access: yesBMC Research Notes, 2018
Objective Based on studies in India (as there was no studies from outside India) amphotericin B deoxycholate has been considered as a backup drug for treatment of visceral leishmaniasis.
Md Golam Hasnain   +7 more
doaj   +1 more source

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines

open access: yeseJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer   +6 more
wiley   +1 more source

Visceral Leishmaniasis [PDF]

open access: yesMayo Clinic Proceedings, 2016
Giuseppe, Famularo, Stefano, Mancini
openaire   +3 more sources

Modular Nanosensing Platforms for Tuberculosis and Beyond: Engineering Biomaterials Toward Cross‐Pathogen Diagnostic Universality

open access: yesMedComm – Biomaterials and Applications, Volume 4, Issue 4, December 2025.
Modular nanosensing platforms utilize nanomaterials and functionalized interfaces to amplify trace different pathogens (like tuberculosis) antigen capture, suppress matrix interference, and enable multiplex detection. Their portability and cost‐effectiveness support rapid screening in resource‐limited settings and real‐time monitoring, advancing high ...
Mei Li   +6 more
wiley   +1 more source

Comparative genomics of canine-isolated Leishmania (Leishmania) amazonensis from an endemic focus of visceral leishmaniasis in Governador Valadares, southeastern Brazil

open access: yesScientific Reports, 2017
Leishmaniasis is a highly diverse group of diseases caused by kinetoplastid of the genus Leishmania. These parasites are taxonomically diverse, with human pathogenic species separated into two subgenera according to their development site inside the ...
H. Valdivia   +10 more
semanticscholar   +1 more source

The State of Public Health in Somalia: Top 5 Challenges and Strategies for Improvement

open access: yesPublic Health Challenges, Volume 4, Issue 4, December 2025.
Somalia's public health system is severely strained by five interconnected challenges: inadequate WASH infrastructure, widespread malnutrition and food insecurity, high burden of infectious diseases, critical gaps in maternal and child health, and the rising prevalence of noncommunicable diseases (NCDs).
Yusuf Hared Abdi   +4 more
wiley   +1 more source

Skin parasite landscape determines host infectiousness in visceral leishmaniasis

open access: yesNature Communications, 2017
Increasing evidence suggests that the infectiousness of patients for the sand fly vector of visceral leishmaniasis is linked to parasites found in the skin.
J. Doehl   +10 more
semanticscholar   +1 more source

Mitochondrial Dysfunction Induced by a Novel Salicylate‐Based 1,2,3‐Triazole Salt With Potent Antileishmanial Activity

open access: yesChemical Biology &Drug Design, Volume 106, Issue 6, December 2025.
A novel salicylate‐based 1,2,3‐triazole salt was synthesized and demonstrated potent and selective activity against Leishmania amazonensis. The most active compound induced mitochondrial dysfunction without hemolytic effects. In silico analyses also suggested favorable pharmacokinetic properties and oral bioavailability.
Bruno A. De Oliveira   +8 more
wiley   +1 more source

Laboratory diagnosis of human visceral leishmaniasis.

open access: yesJournal of Vector Borne Diseases, 2016
Visceral leishmaniasis (VL), caused by the Leishmania donovani complex, is a vector-borne systemic disease, with a worldwide distribution causing high morbidity and mortality in the developing world.
H. Sakkas, C. Gartzonika, S. Levidiotou
semanticscholar   +1 more source

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