Results 81 to 90 of about 55,278 (277)

Therapeutic Options for Visceral Leishmaniasis [PDF]

open access: yesDrugs, 2013
Visceral leishmaniasis (VL), also known as Kala-Azar, is a disseminated protozoal infection caused principally by Leishmania donovani and Leishmania infantum (known as Leishmania chagasi in South America). The therapeutic options for VL are diverse and depend on different factors, such as the geographical area of the infection, development of ...
Begoña Monge-Maillo   +1 more
openaire   +3 more sources

Protein Spatial Structure Meets Artificial Intelligence: Revolutionizing Drug Synergy–Antagonism in Precision Medicine

open access: yesAdvanced Science, Volume 12, Issue 33, September 4, 2025.
This review comprehensively examines the applications of protein three‐dimensional structures and artificial intelligence in investigating drug synergistic and antagonistic effects. The research findings provide compelling evidence for the precision treatment of cancer and metabolic diseases, thereby promoting the development of personalized medicine ...
Anqi Lin   +11 more
wiley   +1 more source

Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani [PDF]

open access: yes, 2020
A chemically diverse range of novel tetraoxanes was synthesized and evaluated in vitro against intramacrophage amastigote forms of Leishmania donovani. All 15 tested tetraoxanes displayed activity, with IC50 values ranging from 2 to 45 µm.
Amado, Patrícia   +5 more
core   +1 more source

Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles

open access: yesChemistry &Biodiversity, Volume 22, Issue 9, September 2025.
The study obtained biopolymeric nanoparticles containing carvacrol (NPCar) and evaluated their anti‐leishmanial activity. NPCar obtained presented physicochemical characteristics due to its ideal nanometric size and zeta potential, and low polydispersity index.
Joyce Cordeiro Borges   +6 more
wiley   +1 more source

Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations

open access: yesHealth Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control strategies, particularly in endemic regions.
Bahareh Abtahi‐Naeini   +5 more
wiley   +1 more source

Interventions for visceral leishmaniasis

open access: yesCochrane Database of Systematic Reviews, 2010
Reason for withdrawal from publication This protocol is being withdrawn from The Cochrane Library. The authors have made no progress with this protocol in seven years. The protocol is out of date and does not meet the current methodological standards of Cochrane.
Urbà González   +6 more
openaire   +3 more sources

The Role of Mathematical Modelling in Predicting and Controlling Infectious Disease Outbreaks in Underserved Settings: A Systematic Review and Meta‐Analysis

open access: yesPublic Health Challenges, Volume 4, Issue 3, September 2025.
ABSTRACT Background and Aim Mathematical modelling plays an important role in public health by enabling the prediction of disease outbreaks, assessment of transmission dynamics and evaluation of intervention strategies. Although widely applied in high‐resource settings, its use in underserved contexts remains underexplored. This review aimed to examine
Mavhunga Khumbudzo   +3 more
wiley   +1 more source

Seroepidemiology of Visceral Leishmaniasis In Ardabil Province During 2002-2011 [PDF]

open access: yes
Background & Objectives: Visceral leishmaniasis is caused by a protozoan called Leishmania, that is a fatal disease for human. In Iran, this disease is caused by Leishmania infantum and occurres in early ages.
امدادی, داريوش   +2 more
core  

Incidence of Trypanosoma cruzi infection in two Guatemalan communities.

open access: yes, 2004
The prevalence of human infection by Trypanosoma cruzi was assessed using an enzyme-linked immunosorbent assay (ELISA) in a serological survey in 1998 of 2 rural communities (SMH and PS) in Guatemala.
Davies, C   +6 more
core   +1 more source

Predicting the distribution of canine leishmaniasis in western Europe based on environmental variables. [PDF]

open access: yes, 2011
The domestic dog is the reservoir host of Leishmania infantum, the causative agent of zoonotic visceral leishmaniasis endemic in Mediterranean Europe. Targeted control requires predictive risk maps of canine leishmaniasis (CanL), which are now explored ...
ADRIAN MYLNE   +21 more
core   +2 more sources

Home - About - Disclaimer - Privacy