Results 81 to 90 of about 226,280 (311)

Clinical and Immunopathological Aspects of Cutaneous, Mucocutaneous, Visceral, and Post-kala-azar Leishmaniasis

open access: yesJournal of Zoonotic Diseases, 2023
The disease Leishmaniasis is a neglected illness with two major forms clinically including cutaneous leishmaniasis and visceral leishmaniasis. From almost 100 endemic countries, an estimated one million additional records of leishmaniasis each year are
Basim Saleem Ahmed Al Sulivany   +1 more
doaj   +1 more source

Bidirectional Interaction Between Liposomal Amphotericin B Pharmacokinetics and Parasite Dynamics in Patients With Post‐Kala‐Azar Dermal Leishmaniasis: Potential Implications for Optimal Dosing

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 437-446, February 2026.
Post‐kala‐azar dermal leishmaniasis (PKDL) involves a high macrophage burden in which the Leishmania parasites reside. Liposomal amphotericin B (LAmB) plays a key role in the treatment of PKDL. The mononuclear phagocyte system (MPS) is crucial in the distribution of liposomal drugs as well as the leishmaniasis pathophysiology.
Wan‐Yu Chu   +12 more
wiley   +1 more source

Geographic distribution and spatial analysis of Leishmania infantum infection in domestic and wild animal reservoir hosts of zoonotic visceral leishmaniasis in Iran: A systematic review

open access: yesJournal of Vector Borne Diseases, 2018
Visceral leishmaniasis (VL) is an important parasitic disease which is endemic in different parts of Iran; and domestic and wild canines are principal reservoir hosts of the disease.
M. Mohebali, E. Moradi-Asl, Y. Rassi
semanticscholar   +1 more source

Urine as a promising sample for Leishmania DNA extraction in the diagnosis of visceral leishmaniasis – a review

open access: yesBrazilian Journal of Infectious Diseases, 2019
Visceral leishmaniasis is a serious and debilitating infection with high fatality rate in tropical and subtropical countries. As clinical symptoms of visceral leishmaniasis are not so specific, confirmatory diagnostic methods with high sensitivity and ...
Gilberto Silva Nunes Bezerra   +4 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Effectiveness of dog collars impregnated with 4% deltamethrin in controlling visceral leishmaniasis in Lutzomyia longipalpis (Diptera: Psychodidade: Phlebotominae) populations

open access: yesMemórias do Instituto Oswaldo Cruz, 2018
BACKGROUND There is little information on the effect of using deltamethrin-impregnated dog collars for the control of canine visceral leishmaniasis. OBJECTIVES The objective of this study was to evaluate the effectiveness of the use of 4% deltamethrin ...
R. A. Silva   +6 more
semanticscholar   +1 more source

A case report on para-kala-azar dermal leishmaniasis: an unresolved mystery

open access: yesBMC Infectious Diseases, 2023
Background Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that occurs 2–3 years after an apparently successful treatment of visceral leishmaniasis (VL).
Md. Mehedi Hasan   +6 more
doaj   +1 more source

Unveiling the Leishmanicidal Mechanism of 4‐Nerolidylcatechol Isolated From Piper peltatum Against Leishmania infantum

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti   +8 more
wiley   +1 more source

Histological Disorganization of Spleen Compartments and Severe Visceral Leishmaniasis

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
The spleen is a secondary lymphoid organ responsible for immune surveillance against blood-circulating pathogens. Absence of the spleen is associated with increased susceptibility to systemic spread and fatal infection by different pathogens.
M. D. Hermida   +4 more
semanticscholar   +1 more source

Leishmaniasis–HIV coinfection: current challenges

open access: yesHIV/AIDS: Research and Palliative Care, 2016
José Angelo Lauletta Lindoso,1,2 Mirella Alves Cunha,3 Igor Thiago Queiroz,4 Carlos Henrique Valente Moreira2 1Laboratory of Soroepidemiology (LIM HC-FMUSP), São Paulo University, São Paulo, 2Instituto de Infectologia Emilio ...
Lindoso JAL   +3 more
doaj  

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