The First Genomic Analysis of Visna/Maedi Virus Isolates in China [PDF]
Visna/Maedi virus (VMV) is a neglected pathogen that damages sheep and goats' nervous and respiratory systems. The virus was discovered 80 years ago and has been endemic in China for nearly four decades; nevertheless, there is little information ...
Jian-Yong Wu +6 more
doaj +5 more sources
Role of alveolar macrophages in respiratory transmission of visna/maedi virus. [PDF]
ABSTRACTA major route of transmission ofVisna/maedi virus(VMV), an ovine lentivirus, is thought to be via the respiratory tract, by inhalation of either cell-free or cell-associated virus. In previous studies, we have shown that infection via the lower respiratory tract is much more efficient than via upper respiratory tissues (T. N.
McNeilly TN +6 more
europepmc +8 more sources
Ovine TRIM5α can restrict visna/maedi virus. [PDF]
ABSTRACT The restrictive properties of tripartite motif-containing 5 alpha (TRIM5α) from small ruminant species have not been explored. Here, we identify highly similar TRIM5α sequences in sheep and goats. Cells transduced with ovine TRIM5α effectively restricted the lentivirus visna/maedi virus DNA synthesis.
Jáuregui P +9 more
europepmc +8 more sources
Seroprevalence of Visna-Maedi Virus (VMV) and Border Disease Virus (BDV) in Van province and around [PDF]
The present study investigated the seroprevalance of Visna Maedi Virus (VMV) and Border Disease Virus (BDV) infections in sheeps in regions in and around Van province, Turkey. Sample materials were taken from 360 sheep sent to slaughterhouses around Van.
P.S. Mohammad Ameen, Z. Karapınar
doaj +7 more sources
Identification of the ovine mannose receptor and its possible role in Visna/Maedi virus infection. [PDF]
This study aims to characterize the mannose receptor (MR) gene in sheep and its role in ovine visna/maedi virus (VMV) infection. The deduced amino acid sequence of ovine MR was compatible with a transmembrane protein having a cysteine-rich ricin-type ...
Crespo H +9 more
europepmc +9 more sources
Characterization of minimal lesions related to the presence of visna/maedi virus in the mammary gland and milk of dairy sheep. [PDF]
BackgroundIn order to characterize the complete range of lesions, especially minimal, affecting mammary gland and viral antigen distribution and target cells using immunohistochemistry in naturally Visna/maedi (VM) 84 infected sheep were studied, forty ...
Gayo E +8 more
europepmc +2 more sources
Persistent expression of Ia antigen and viral genome in visna-maedi virus-induced inflammatory cells. Possible role of lentivirus-induced interferon [PDF]
In this study we investigated the pathogenesis of the lymphoproliferative response in the chronic-active visna maedi virus- induced inflammatory lesions.
P. Kennedy +5 more
semanticscholar +2 more sources
Characterization of the lymphocytic alveolitis in visna‐maedi virus‐induced interstitial lung disease of sheep [PDF]
SUMMARYIn order to investigate the contribution of lymphocytes to interstitial lung disease in animals with visna-maedi infection, we studied in parallel bronchoalveolar cells and lung tissue from slaughterhouse animals (n = 29) and from colostrum-deprived lambs transtracheally inoculated with field isolates of visna-maedi virus (n = 9) or saline (n ...
G. Cordier +5 more
semanticscholar +3 more sources
Effects of housing on the incidence of visna/maedi virus infection in sheep flocks. [PDF]
The incidence of seroconversion to visna/maedi virus (VMV) infection and its relationship with management and sheep building structure was investigated in 15 dairy sheep flocks in Spain during 3-7years. Incidence rates were 0.09 per sheep-year at risk in semi-intensive Latxa flocks and 0.44 per sheep-year at risk in intensive Assaf flocks and was ...
I. Leginagoikoa +8 more
semanticscholar +4 more sources
Experimental infection of sheep with visna/maedi virus via the conjunctival space.
Experiments were performed to determine whether visna/maedi virus (VMV), a small ruminant lentivirus (SRLV), could infect sheep via ocular tissues. The EV1 strain of VMV was administered into the conjunctival space of uninfected sheep, and the animals ...
H. Niesalla +4 more
semanticscholar +4 more sources

