Results 91 to 100 of about 4,116,225 (362)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

An Optical Coherence Tomography-Based Deep Learning Algorithm for Visual Acuity Prediction of Highly Myopic Eyes After Cataract Surgery

Frontiers in Cell and Developmental Biology, 2021
BackgroundDue to complicated and variable fundus status of highly myopic eyes, their visual benefit from cataract surgery remains hard to be determined preoperatively.
Ling Wei, Ling Wei, Ling Wei, Wenwen He, Wenwen He, Wenwen He, Jinrui Wang, Keke Zhang, Keke Zhang, Keke Zhang, Yu Du, Yu Du, Yu Du, Jiao Qi, Jiao Qi, Jiao Qi, Jiaqi Meng, Jiaqi Meng, Jiaqi Meng, Xiaodi Qiu, Xiaodi Qiu, Xiaodi Qiu, Lei Cai, Lei Cai, Lei Cai, Qi Fan, Qi Fan, Qi Fan, Zhennan Zhao, Zhennan Zhao, Zhennan Zhao, Yating Tang, Yating Tang, Yating Tang, Shuang Ni, Haike Guo, Yunxiao Song, Xixi He, Dayong Ding, Yi Lu, Yi Lu, Yi Lu, Xiangjia Zhu, Xiangjia Zhu, Xiangjia Zhu   +44 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Quality of life and visual function in Nigeria: findings from the National Survey of Blindness and Visual Impairment [PDF]

, 2011
Aims To assess associations of visual function (VF) and quality of life (QOL) by visual acuity (VA), causes of blindness and types of cataract procedures in Nigeria. Methods Multi-stage stratified cluster random sampling was used to identify a nationally
Abubakar, T, Bankole, OO, Ezelum, CC, Gilbert, CE, Gudlavalleti, MVS, Mahdi, AM, Nigeria Natl, B, Shah, SP, Sivasubramaniam, S, Tran, HM, Visual, I   +10 more
core   +1 more source

Prevalence, Causes and Social Factors of Visual Impairment among Chinese Adults: Based on a National Survey

International Journal of Environmental Research and Public Health, 2017
Visual impairment has become a global challenge, especially for developing countries. This study aims to estimate the prevalence, causes and social factors of visual impairment among Chinese adults.
C. Guo, Zhenjie Wang, P. He, Gong Chen, Xiaoying Zheng   +4 more
semanticscholar   +1 more source

Visual impairment following aluminum phosphide poisoning: A rare case [PDF]

, 2023
Alireza Kargar, Maryam Noroozıan, Mahtab Ramezani, Shahin Shadnia, Babak Mostafazadeh, Peyman Erfan Talab Evini, Mitra Rahimi   +6 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Stroke survivors’ views and experiences on impact of visual impairment

Brain and Behavior, 2017
We sought to determine stroke survivors’ views on impact of stroke‐related visual impairment to quality of life.
F. Rowe
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalk

Stem Cell Research & Therapy
Background Stem cell-derived secreted factors could protect neurons in neurodegenerative disease or after injury. The exact neuroprotective components in the secretome remain challenging to discover.
Qing Xia, Kun-Che Chang, Yanan Sun, Michael Nahmou, Takahiko Noro, Yun Cheng, Xiangmei Kong, Xiaofen Mo, Jeffrey L. Goldberg, Suqian Wu   +9 more
doaj   +1 more source