Results 71 to 80 of about 521,031 (345)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

‘This is the core of what we do’: a qualitative study of social prescribers’ attitudes towards spiritual health training and their future training needs

BMC Primary Care
Background Despite the evidence supporting the importance of spiritual health to people’s wellbeing across diverse fields of treatment, the topic of spiritual health is not currently mentioned in National Health Service (NHS) training materials for ...
Mark Adley, Alexandra Thompson, Philip Mordue, Amy O’Donnell, Barbara Hanratty, Ishbel Orla Whitehead   +5 more
doaj   +1 more source

Technical Diagnostics of Ventilation Units for Energy Efficiency and Safety of Operation

E3S Web of Conferences, 2017
The article considers the questions of application of technical diagnostics fan installations methods for providing safe operation, the system of the technical maintenance improvement and repair.
Kuzin Evgeny, Shahmanov Vitality, Dubinkin Dmitriy   +2 more
doaj   +1 more source

Clinical prevalence of Lewy body dementia

Alzheimer’s Research & Therapy, 2018
Background The prevalence of dementia with Lewy bodies (DLB) and dementia in Parkinson’s disease (PDD) in routine clinical practice is unclear. Prevalence rates observed in clinical and population-based cohorts and neuropathological studies vary greatly.
Joseph P. M. Kane, Ajenthan Surendranathan, Allison Bentley, Sally A. H. Barker, John-Paul Taylor, Alan J. Thomas, Louise M. Allan, Richard J. McNally, Peter W. James, Ian G. McKeith, David J. Burn, John T. O’Brien   +11 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

The Evolution and Vitality of Merger Presumptions: A Decision-Theoretic Approach [PDF]

, 2015
This article reviews the formulation and evolution of the Philadelphia National Bank anticompetitive presumption through the lens of decision theory and Bayes Law.
Salop, Steven C.
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Discussing spiritual health in primary care and the HOPE tool - a survey of social prescribers

BMC Primary Care
Background Social prescribing aims to provide holistic care to patients and reduce health inequalities by meeting needs that expand beyond the biomedical model, as detailed in the National Health Service (NHS)’s Long Term Plan.
Ishbel Orla Whitehead, Philip Mordue, Mark Adley, Amy O’Donnell, Barbara Hanratty   +4 more
doaj   +1 more source

Disease activity flares and pain flares in an early rheumatoid arthritis inception cohort; characteristics, antecedents and sequelae [PDF]

, 2019
© 2019 The Author(s). This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium ...
Ferguson, Eamonn, James, Richard J E, Kiely, Patrick D W, McWilliams, Daniel F, Rahman, Shimin, Walsh, David A, Young, Adam   +6 more
core   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source