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Çocuklarda vitamin B12 düzeyleri ile tam kan parametreleri arasındaki ilişkinin değerlendirilmesi
Amaç: Vitamin B12 insan vücudunda üretilemeyen ve sadece hayvansal gıdalar ile alınan bir vitamindir. Vitamin B12 DNA sentezinde önemli rol oynar ve eksikliğinde DNA sentezi bozulur. Sonuç olarak megaloblastik anemi gelişir.
Ömer Kartal, Orhan Gürsel
doaj +1 more source
The biosynthesis of B12, involving up to 30 different enzyme-mediated steps, only occurs in bacteria. Thus, most eukaryotes require an external source of B12, and yet the vitamin appears to have only two functions in eukaryotes: as a cofactor for the enzymes methionine synthase and methylmalonylCoA mutase.
Smith, A. David+2 more
openaire +6 more sources
Vitamin B12 Deficiency Alters the Gut Microbiota in a Murine Model of Colitis
Purpose: Inflammatory bowel disease (IBD) refers to a spectrum of autoimmune diseases, which result in chronic intestinal inflammation. Previous findings suggest a role for diet, nutrition and dysbiosis of the gut microbiota in both the development and ...
Eberhard Lurz+10 more
semanticscholar +1 more source
Evaluation of vitamin B12 monitoring in patients on metformin in urban ambulatory care settings
Background: Previous studies linked metformin use to vitamin B12 deficiency and demonstrated that the prevalence of vitamin B12 monitoring remains low. Objective: This study aimed to assess the occurrence of monitoring vitamin B12 levels in a diverse ...
Longo SL+5 more
doaj +1 more source
Objective: Syncope is a frequent reason for referral to pediatric cardiology clinics. Vitamin B12 deficiency is frequently diagnosed in pediatric patients.
Süleyman Sunkak, Mustafa Argun
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An association between neuropsychiatric disorders and vitamin B12 deficiency has been recognized since 1849 when pernicious anaemia was first described. It has been suggested that deficiency of vitamin B12 might contribute to age-associated cognitive impairment. Low serum vitamin B12 concentrations are found in more than 10% of older people.
Malouf, R, Areosa Sastre, A
openaire +5 more sources
Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depression
Depression is a common mental health condition occurring across all ages, genders, and populations and is almost always multifaceted. It can manifest as a form of metabolic disorder, endocrine disorder, cardiovascular diseases, inflammatory disorders ...
Prerna Sangle+4 more
semanticscholar +1 more source
Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia
Background Vitamin B12 deficiency is linked to impaired cognition and memory along with a sensation of tingling and numbness, an outcome of poor myelination. Elevated methylmalonic acid and serum homocysteine levels are markers of Vitamin B12 deficiency.
S. Jatoi+5 more
semanticscholar +1 more source
Vitamin B12 is essential for DNA and RNA synthesis. Vitamin B12 deficiency usually occurs in infants who are exclusively breastfed born to Vitamin B12-deficient mothers.
K Jagadish Kumar+3 more
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Serum vitamin B12 associated with vitamin D/25(OH)D in women with recurrent aphthous stomatitis.
Vitamin B12 and Vitamin D deficiency may contribute to recurrent aphthous stomatitis (RAS). Current studies have showed vitamin B12 to be associated with vitamin D in women, however no study has assessed vitamin B12 associated with vitamin D/25(OH)D in ...
Hendri Susanto+5 more
doaj +1 more source