Results 81 to 90 of about 797,518 (380)

Characterization of Vitamin B12 Supplementation and Correlation with Clinical Outcomes in a Large Longitudinal Study of Early Parkinson's Disease. [PDF]

, 2019
ObjectiveIn Parkinson's disease (PD), vitamin B12 levels are lower, and comorbid B12 deficiency has been associated with the development of neuropathy and early gait instability.
Christine, Chadwick W, Dietiker, Cameron, Kim, Soeun, Zhang, Yunxi   +3 more
core  

Association of vitamin B12 with pro-inflammatory cytokines and biochemical markers related to cardiometabolic risk in Saudi subjects [PDF]

, 2016
Background: This study aimed to examine the relationship between changes in systemic vitamin B12 concentrations with pro-inflammatory cytokines, anthropometric factors and biochemical markers of cardiometabolic risk in a Saudi population.
Al-Attas, O.S., Al-Attas, O.S., Al-Daghri, N.M., Al-Daghri, N.M., Alokail, M.S., Alokail, M.S., McTernan, P.G., McTernan, P.G., Rahman, S., Rahman, S., Sabico, S., Sabico, S., Saravanan, P., Saravanan, P., Tripathi, G., Tripathi, G., Wani, K., Wani, K., Yakout, S., Yakout, S.   +19 more
core   +3 more sources

Pharmacokinetics of inorganic cobalt and a vitamin B12 supplement in the thoroughbred horse: differentiating cobalt abuse from supplementation [PDF]

, 2018
Background While cobalt is an essential micronutrient for vitamin B12 synthesis in the horse, at supraphysiological concentrations, it has been shown to enhance performance in human subjects and rats, and there is evidence that its administration in ...
Ho, Jelkmann, Knych, Lippi, McDowell, Saxena   +5 more
core   +2 more sources

A Refined Adaptive Laboratory Evolution Strategy With Biosensor‐Assisted Selection Resolves the Tolerance–Efficiency Trade‐Off in Toxic Chemical Biosynthesis

Advanced Science, EarlyView.
This study presents a refined adaptive laboratory evolution (ALE) strategy to resolve the trade‐off between tolerance and biosynthetic efficiency in toxic chemical production. Combining in vivo mutagenesis, microdroplet‐based evolution, and biosensor‐assisted selection, this strategy rapidly yields robust “win‐win” phenotypes.
Yufei Zhang, Junhua Yun, Guoyan Zhang, Hossain M. Zabed, Yuehui Tian, Xinrui Tang, Jia Li, Xianghui Qi   +7 more
wiley   +1 more source

Vitamin B12 in Relation to Oxidative Stress: A Systematic Review

Nutrients, 2019
The triage theory posits that modest micronutrient deficiencies may induce reallocation of nutrients to processes necessary for immediate survival at the expense of long-term health.
Erik E van de Lagemaat, L. D. de Groot, E. G. van den Heuvel   +2 more
semanticscholar   +1 more source

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

Advanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang, Ke Fang, Wuyan Lu, Rongrong Wu, Yuanyuan Chen, Linxiao Li, Zihao Hu, Zixin Cai, Yu Jiang, Xinli Fan, Jinyi Deng, Guangpeng Liu, Zhuang Luo, Lei Cui, Shuaijun Li   +14 more
wiley   +1 more source

Vitamin B12 status in patients of Turkish and Dutch descent with depression: A comparative cross-sectional study [PDF]

, 2009
Background: Studies have shown a clear relationship between depressive disorders and vitamin B12 deficiency. Gastroenteritis and Helicobacter pylori infections can cause vitamin B12 deficiency. Helicobacter pylori infections are not uncommon among people
A Coppen, A Hvas, AC Vries de, AH Ford, AT Beck, B Spitzer, BR Hutto, BW Penninx, CR Santhosh-Kumar, D Mischoulon, DF Horrobin, E Serin, G Parker, H Tiemeier, HG Ruhe, J Hintikka, J Lindenbaum, J Selhub, JM Kim, K Kaptan, K Nilsson, KM Riggs, L Clement, L Pezawas, M Folstein, M Hamilton, MH Kamphuis, NP Rao, Peter van Loon, PG Dagnelie, RJ Loffeld, RJ Loffeld, SA Lipton, TB Robins Wahlin, Y Gumurdulu, Yener Güzelcan   +35 more
core   +6 more sources

Suppressing Glycerol‐3‐phosphate Phosphatase and Enhancing Glycerol‐3‐Phosphate Shuttle Flux Crucial for High‐Efficiency Fatty Acid Production in the Fast‐Growing Oleaginous Schizochytrium

Advanced Science, EarlyView.
This study establishes an efficient oleaginous heterotrophic microalga, Schizochytrium, through chassis optimization and metabolic engineering, significantly enhancing fatty acid titers and productivities. It also identifies a regulatory mechanism that coordinates biomass and lipid synthesis, providing a rational target for metabolic pathway rewiring ...
Fangzhong Wang, Weijia Jin, Tiantian Wang, Junkai Ji, Kun Cao, Jianqiang Li, Lei Chen, Weiwen Zhang   +7 more
wiley   +1 more source

The status of vitamin B12 and folate among Chinese women: a population-based cross-sectional study in northwest China. [PDF]

PLoS ONE, 2014
OBJECTIVE: To assess the status of the vitamin B12 and folate of Chinese women living in northwest China. METHODS: A population-based cross-sectional study was conducted in 2008 among Chinese women aged 10-49 years living in Shaanxi province of northwest
Shaonong Dang, Hong Yan, Lingxia Zeng, Quanli Wang, Qiang Li, Shengbin Xiao, Xiaojing Fan   +6 more
doaj   +1 more source

Vitamin B12 deficiency common in primary hypothyroidism [PDF]

, 2008
OBJECTIVE: To assess the prevalence and clinical features of B12 deficiency in hypothyroid patients and to evaluate clinical response in symptoms to B12 replacement therapy.
Akhter, J., Islam, Najmul, Jabbar, Abdul, Khan, Ataullah, Ul Haque, Naeem, Waseem, Sabiha, Yawar, Aasma, Zuberi, Lubna   +7 more
core   +1 more source