Results 1 to 10 of about 350,349 (219)

Immunostimulatory effects of vitamin B5 improve anticancer immunotherapy [PDF]

OncoImmunology, 2022
Vitamin B5 (panthotenic acid), the precursor of coenzyme A (CoA), is contained in most food items and is produced by the intestinal microbiota. A recent study published in Cell Metabolism reports that vitamin B5 and CoA favor the differentiation of CD8 ...
Melanie Bourgin, Oliver Kepp, Guido Kroemer   +2 more
doaj   +7 more sources

Association between plasma Vitamin B5 levels and all‐cause mortality: A nested case‐control study [PDF]

The Journal of Clinical Hypertension, 2022
We aimed to evaluate the prospective association of vitamin B5 with all‐cause mortality and explore its potential modifiers in Chinese adults with hypertension.
Yuan Hong, Ziyi Zhou, Nan Zhang, Qiangqiang He, Zhangyou Guo, Lishun Liu, Yun Song, Ping Chen, Yaping Wei, Qiuyue Xu, Ya Li, Binyan Wang, Xianhui Qin, Xiping Xu, Yong Duan   +14 more
doaj   +3 more sources

The genome and lifestage-specific transcriptomes of a plant-parasitic nematode and its host reveal susceptibility genes involved in trans-kingdom synthesis of vitamin B5 [PDF]

Nature Communications, 2022
Plant-parasitic nematodes are a threat to crop production. Combining bioinformatics, genetic and biochemical approaches, the authors show that the plant pathogen beet cyst nematode possesses an incomplete vitamin B5 synthesis pathway, of potential ...
Shahid Siddique, Zoran S. Radakovic, Clarissa Hiltl, Clement Pellegrin, Thomas J. Baum, Helen Beasley, Andrew F. Bent, Oliver Chitambo, Divykriti Chopra, Etienne G. J. Danchin, Eric Grenier, Samer S. Habash, M. Shamim Hasan, Johannes Helder, Tarek Hewezi, Julia Holbein, Martijn Holterman, Sławomir Janakowski, Georgios D. Koutsovoulos, Olaf P. Kranse, Jose L. Lozano-Torres, Tom R. Maier, Rick E. Masonbrink, Badou Mendy, Esther Riemer, Mirosław Sobczak, Unnati Sonawala, Mark G. Sterken, Peter Thorpe, Joris J. M. van Steenbrugge, Nageena Zahid, Florian Grundler, Sebastian Eves-van den Akker   +32 more
doaj   +3 more sources

Association between plasma vitamin B5 and coronary heart disease: Results from a case-control study [PDF]

Frontiers in Cardiovascular Medicine, 2022
AimThe relationship of vitamin B5 and coronary heart disease (CHD) is still uncertain. This case–control study was performed to evaluate the relationship between the plasma vitamin B5 concentration and the risk of CHD.Materials and methodsThe study ...
Pengfei Sun, Haoyu Weng, Fangfang Fan, Nan Zhang, Zhihao Liu, Ping Chen, Jia Jia, Bo Zheng, Tieci Yi, Yuxi Li, Yan Zhang, Yan Zhang, Jianping Li, Jianping Li   +13 more
doaj   +2 more sources

Vitamin B5 supports anti-PD1 response in HER2-positive gastric cancer and enhances interaction between naïve B cells and T cells [PDF]

Nature Communications
The cellular mechanisms underlying HER2-positive gastric cancer (HER2+ GC) responses to immunochemotherapy remain underexplored. Here, we perform longitudinal single-cell RNA-sequencing with paired TCR/BCR profiling on HER2+ and HER2-negative gastric ...
Chaoye Wang, Jing Yang, Ming-Yu Lai, Jia-Chen Lu, Li-Qiong Yang, Zhi-Ying Wu, Hai-Yan Zhang, Fang Wang, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Feng-Hua Wang, Wen-Long Guan, Ying Jin, Rui-Hua Xu, Qi Zhao, Miao-Zhen Qiu   +16 more
doaj   +2 more sources

Molecular Properties of Bare and Microhydrated Vitamin B5-Calcium Complexes. [PDF]

Int J Mol Sci, 2021
Pantothenic acid, also called vitamin B5, is an essential nutrient involved in several metabolic pathways. It shows a characteristic preference for interacting with Ca(II) ions, which are abundant in the extracellular media and act as secondary mediators in the activation of numerous biological functions. The bare deprotonated form of pantothenic acid,
Corinti D, Chiavarino B, Scuderi D, Fraschetti C, Filippi A, Fornarini S, Crestoni ME.   +6 more
europepmc   +5 more sources

Vitamin B5 is a context-dependent dietary regulator of nociception. [PDF]

G3 (Bethesda)
Abstract Chronic pain has an enormous impact on the quality of life of billions of patients, families, and caregivers worldwide. Current therapies do not adequately address pain for most patients. A basic understanding of the conserved genetic framework controlling pain may help us develop better, non-addictive pain therapies.
Hamoudi Z, Leung C, Khuong TM, Cooney G, Neely GG.   +4 more
europepmc   +3 more sources

Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington’s Disease [PDF]

Metabolites, 2019
Huntington’s disease (HD) is a neurodegenerative disorder caused by an expanded CAG repeat in exon 1 of the HTT gene. HD usually manifests in mid-life with loss of GABAergic projection neurons from the striatum accompanied by progressive atrophy of the ...
Stefano Patassini, Paul Begley, Jingshu Xu, Stephanie J. Church, Nina Kureishy, Suzanne J. Reid, Henry J. Waldvogel, Richard L. M. Faull, Russell G. Snell, Richard D. Unwin, Garth J. S. Cooper   +10 more
doaj   +2 more sources

Vitamin B5 and vitamin U review: justification of combined use for the treatment of mucosa-associated gastrointestinal pathologies [PDF]

Frontiers in Pharmacology
Inflammatory and erosive lesions of the gastrointestinal mucosa encompass many conditions presenting significant challenges to public health worldwide.
Valentin P. Shichkin
doaj   +2 more sources

Development and validation of age- and sex-specific reference intervals for serum vitamin B5 in Henan pediatric population by LC-MS/MS [PDF]

Frontiers in Nutrition
Background and objectiveReference intervals (RIs) for serum vitamin B5 (pantothenic acid, B5) specific to the Henan pediatric population have not been established. Current clinical practice, in China continues to rely on reference thresholds derived from
Yusheng Luan, Yusheng Luan, Tiewei Li, Fatao Lin, Xiaojuan Li, Junmei Yang   +5 more
doaj   +2 more sources