Results 11 to 20 of about 350,349 (219)

PI3K drives the de novo synthesis of coenzyme A from vitamin B5. [PDF]

Nature, 2022
Abstract In response to hormones and growth factors, the class I phosphoinositide-3-kinase (PI3K) signalling network functions as a major regulator of metabolism and growth, governing cellular nutrient uptake, energy generation, reducing cofactor production and macromolecule biosynthesis 1
Dibble CC, Barritt SA, Perry GE, Lien EC, Geck RC, DuBois-Coyne SE, Bartee D, Zengeya TT, Cohen EB, Yuan M, Hopkins BD, Meier JL, Clohessy JG, Asara JM, Cantley LC, Toker A.   +15 more
europepmc   +3 more sources

Effect of Vitamin B5 on Liver Enzyme Levels in Bile Duct Ligation Cholestatic Rat Model

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017
Background and Objectives: Accumulation of toxic bile salts in a bile duct ligation (BDL) animal model plays a pivotal role in the induction of liver fibrosis.
Fatemeh Sadat Emami, Akram Eidi, Pejman Mortazavi, Ahmad Asghari   +3 more
doaj   +1 more source

Vitamin B5 copper conjugated triazine dendrimer improved the visible-light photocatalytic activity of TiO2 nanoparticles for aerobic homocoupling reactions [PDF]

Scientific Reports
In this work, Cu-vitamin B5 (pantothenic acid) bonded to 2,4,6-trichloro-1,3,5-triazine produced a bioconjugated dendrimer giving rise to the visible-light photocatalytic activity of nanocrystalline TiO2.
Samira Zamenraz, Maasoumeh Jafarpour, Ameneh Eskandari, Abdolreza Rezaeifard   +3 more
doaj   +2 more sources

g-C3N4-Vitamin B5-Cu@γ-Fe2O3 as a magnetic nano biocomplex photocatalyzed efficient one pot tandem synthesis of benzimidazoles and imines [PDF]

Scientific Reports
This work introduces a natural-based nanostructured catalyst involving copper complexed with g-C3N4-Vitamin B5 hybrid supported on magnetic nanoparticles as an efficient photocatalytic system.
Maasoumeh Jafarpour, Abdolreza Rezaeifard, Narges Pourmorteza, Nasrin Fouladshekan, Paria Jamshidinajafabadi   +4 more
doaj   +2 more sources

Vitamin B5 supplementation enhances intestinal development and alters microbes in weaned piglets [PDF]

Animal Biotechnology
This study explored the effects of different vitamin B5 (VB5) levels on intestinal growth and function of weaned piglets. Twenty-one piglets (7.20 ± 1.11 kg) were included in a 28-day feeding trial with three treatments, including 0 mg/kg (L-VB5), 10 mg ...
Xin Wang, Yan Qin, Jianzhong Li, Pengfei Huang, Yali Li, Jing Huang, Qiye Wang, Huansheng Yang   +7 more
doaj   +2 more sources

Pantothenic Acid as an Unexpected Cause of Hypersensitivity to Sensitive or Atopic Skin Care Products—A Narrative Review [PDF]

Pharmaceutics
Pantothenic acid (PA; vitamin B5) is an essential component of many key metabolic processes. Vitamin B5 deficiency causes dysfunction in various systems and organs.
Kinga Lis
doaj   +2 more sources

Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis.

Biochem Biophys Res Commun, 2020
Vitamin B5 (d-pantothenic acid; pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA), through which it plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism.
Ismail N, Kureishy N, Church SJ, Scholefield M, Unwin RD, Xu J, Patassini S, Cooper GJS.   +7 more
europepmc   +3 more sources

A pantothenic acid deficiency outbreak causing mortality and neuromuscular disorders in newborn and nursery piglets [PDF]

Porcine Health Management
Background The present case report describes the clinical and pathological outcomes of an outbreak of piglet mortality and neuromuscular disorders in newborn and nursery piglets caused by vitamin B5 deficiency.
Sara Isabel Loscertales, Anna Romagosa, Laura Martino, Marina Cid-Cañete, Sofía Bosco, Mariona Leiva-Forns, Joaquim Segalés   +6 more
doaj   +2 more sources

VB5 modulates osteoclast metabolic reprogramming and suppresses differentiation by blocking PKM2 nuclear translocation [PDF]

Scientific Reports
Osteoporosis is a multifactorial skeletal disorder characterized by increased bone resorption and impaired remodeling balance. Osteoclast differentiation is accompanied by metabolic reprogramming toward enhanced glycolysis, yet whether nutritional ...
Hongming Zhou, Hengren Li, Ming Fu, Heng Yang, Xingang Cui   +4 more
doaj   +2 more sources

Modular Enzymatic Cascade Synthesis of Vitamin B₅ and Its Derivatives. [PDF]

Chemistry, 2018
Access to vitamin B5 [(R)‐pantothenic acid] and both diastereoisomers of α‐methyl‐substituted vitamin B5 [(R)‐ and (S)‐3‐((R)‐2,4‐dihydroxy‐3,3‐dimethylbutanamido)‐2‐methylpropanoic acid] has been achieved using a modular three‐step biocatalytic cascade ...
Abidin MZ, Saravanan T, Zhang J, Tepper PG, Strauss E, Poelarends GJ.   +5 more
europepmc   +3 more sources