Vitamin B-6 deficiency and renal function and structure in chronically uremic rats
The American Journal of Clinical Nutrition, 1991 In preliminary studies, rats with chronic renal failure (CRF) demonstrated worsening renal function, as measured by urea clearance, when fed vitamin B-6-deficient diets. However, urea clearance is not a precise measure of glomerular filtration rate (GFR) and these studies did not indicate the mechanism for the reduced GFR.
M Wolfson, A H Cohen, Joel D. Kopple
semanticscholar +5 more sources
Pathology Associated with Vitamin B-6 Deficiency in Growing Kittens
The Journal of Nutrition, 1991 Patricia C Blanchard +3 more
semanticscholar +5 more sources
A Mathematical Model of Tryptophan Metabolism via the Kynurenine Pathway Provides Insights into the Effects of Vitamin B-6 Deficiency, Tryptophan Loading, and Induction of Tryptophan 2,3-Dioxygenase on Tryptophan Metabolites [PDF]
Journal of NutriLife, 2013 Vitamin B-6 deficiency is associated with impaired tryptophan metabolism because of the coenzyme role of pyridoxal 5'-phosphate (PLP) for kynureninase and kynurenine aminotransferase.
Luisa Rios‐Avila +4 more
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Journal of NutriLife, 2000 Vitamin B-6 deficiency causes mild elevation in plasma homocysteine, but the mechanism has not been clearly established. Serine is a substrate in one-carbon metabolism and in the transsulfuration pathway of homocysteine catabolism, and pyridoxal ...
Mauricio Martı́nez +4 more
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Hydrolytic Activity toward Pyridoxine-5′-β-d-Glucoside in Rat Intestinal Mucosa Is Not Increased by Vitamin B-6 Deficiency: Effect of Basal Diet Composition and Pyridoxine Intake [PDF]
Journal of NutriLife, 2003 Pyridoxine-5'-beta-D-glucoside (PNG), a glycosylated form of dietary vitamin B-6, is partially hydrolyzed in the small intestine by the cytosolic enzyme pyridoxine-5'-beta-D-glucoside hydrolase (PNG hydrolase) and by the brush border enzyme lactase ...
Amy D. Mackey +3 more
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Journal of NutriLife, 2006 The transsulfuration pathway, which aids in regulating homocysteine concentration and mediates cysteine synthesis, may be sensitive to vitamin B-6 status because cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CGL) require pyridoxal 5 ...
Carolina P Lima +5 more
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Vitamin B-6 deficiency is common and associated with poor long-term outcome in renal transplant recipients, [PDF]
American Journal of Clinical Nutrition, 2017 Background: Previous studies have reported low circulating concentrations of pyridoxal-5-phospate (PLP) in renal transplant recipients (RTRs). It is unknown whether this is because of low intake or altered handling, and it is also unknown whether ...
Isidor Minović +11 more
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Marginal Vitamin B-6 Deficiency Decreases Plasma (n-3) and (n-6) PUFA Concentrations in Healthy Men and Women3 [PDF]
Journal of NutriLife, 2012 Previous animal studies showed that severe vitamin B-6 deficiency altered fatty acid profiles of tissue lipids, often with an increase of linoleic acid and a decrease of arachidonic acid.
Mei Zhao +10 more
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Vitamin B-6 Deficiency Prolongs the Time Course of Evoked Dopamine Release from Rat Striatum [PDF]
Journal of NutriLife, 2004 Vitamin B-6-deficient animals exhibit motor abnormalities. To investigate the possible physiologic alterations in the dopaminergic nervous system in vitamin B-6 deficiency, dopamine release in the striatum of vitamin B-6-deficient rats was determined ...
Fu-In Tang, Ien-Lan Wei
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Journal of NutriLife, 2009 We experimented with a mathematical model for 1-carbon metabolism and glutathione (GSH) synthesis to investigate the effects of vitamin B-6 deficiency on the reaction velocities and metabolite concentrations in this metabolic network.
H. Frederik Nijhout +6 more
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