Results 131 to 140 of about 181,889 (303)
Background: Cardiovascular events are frequent and vascular endothelial function is abnormal in patients with chronic kidney disease (CKD). We demonstrated endothelial dysfunction with vitamin D deficiency in CKD patients; however the impact of ...
Chitalia, N +31 more
core +1 more source
Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei +8 more
wiley +1 more source
Purpose Vitamin C is a fundamental antioxidant with important metabolic actions in several biological processes. Patients with type 2 diabetes (T2D) are exposed to oxidative stress as a consequence of an increased production of reactive oxygen species ...
Anna Toffalini +6 more
doaj +1 more source
Effect of low-dosage vitamin A and riboflavin on iron-folate supplementation in anaemic pregnant women [PDF]
A double-blind, placebo, controlled trial was conducted in Banyudono subdistrict, Boyolali regency, Central Java province, Indonesia. The aim of the study was to determine whether adding low-dosage vitamin A and riboflavin can enhance the effect of ...
Suprapto, Bambang, Widardo,, Suhanantyo,
core
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang +9 more
wiley +1 more source
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang +10 more
wiley +1 more source
Scurvy, the clinical manifestation of chronic vitamin C deficiency, is commonly regarded as a historical disease. Vitamin C (ascorbic acid) is essential for collagen synthesis, carnitine biosynthesis, and neurotransmitter metabolism. Feeding difficulties,
Geo Bertha Fernanda +3 more
doaj +1 more source
Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects
Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu +6 more
wiley +1 more source
Vitamin C Deficiency: an Intradermal Test [PDF]
B, Portnoy, J F, Wilkinson
openaire +2 more sources
Comparison of the Effects of Supplemental Red Palm Oil and Sunflower oil on Maternal Vitamin A Status. [PDF]
Conflicting results have been reported on the ability of dietary carotenoids to improve vitamin A status in lactating women. Red palm oil is one of the richest dietary sources of beta-carotene.
Mugyabuso, J K +7 more
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