Results 71 to 80 of about 794,897 (330)
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Identifying Causal Effects Using Instrumental Variables from the Auxiliary Population [PDF]
arXiv, 2023 Instrumental variable approaches have gained popularity for estimating causal effects in the presence of unmeasured confounding. However, the availability of instrumental variables in the primary population is often challenged due to stringent and untestable assumptions.
arxiv
The Journal Of Prevention of Alzheimer's Disease, 2015 Emerging evidence suggests that low vitamin D concentrations are potentially involved in the pathogenesis of dementia. This is of particular interest when considering the high prevalence of vitamin D deficiency in elderly adults and the urgent need to identify modifiable risk factors for dementia.
Littlejohns, T +4 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Vitamin K content of Australian-grown horticultural commodities [PDF]
Food Chem. 452:139382 (2024)Vitamin K is emerging as a multi-function vitamin that plays a role in bone, brain and vascular health. Vitamin K composition data remain limited globally and Australia has lacked nationally representative data for vitamin K1 (phylloquinone, PK) in horticultural commodities.
arxiv +1 more source
Vitamin D: The "sunshine" vitamin.
Journal of pharmacology & pharmacotherapeutics, 2012 Vitamin D insufficiency affects almost 50% of the population worldwide. An estimated 1 billion people worldwide, across all ethnicities and age groups, have a vitamin D deficiency (VDD). This pandemic of hypovitaminosis D can mainly be attributed to lifestyle (for example, reduced outdoor activities) and environmental (for example, air pollution ...
Arun Maseeh, Rathish Nair
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie +5 more
wiley +1 more source
Педиатрическая фармакология, 2014 Spread of vitamin D deficiency in children of various ages has not been studied in the Russian Federation. Numerous studies of foreign authors indicate high importance of this issue in many regions of the world, including southern territories with high ...
E. A. Potrokhova +5 more
doaj +1 more source
Chronic stress may disrupt covariant fluctuations of vitamin D and cortisol plasma levels in pregnant sheep during the last trimester: a preliminary report [PDF]
arXiv, 2019 Psychosocial stress during pregnancy is a known contributor to preterm birth, but also has been increasingly appreciated as an in utero insult acting long-term on prenatal and postnatal neurodevelopmental trajectories. These events impact many information molecules, including both vitamin D and cortisol.
arxiv
Bone Reports, 2018 Vitamin D is increasingly recognised to play an important role in normal muscle function. Low vitamin D status is associated with an increased risk of falls and proximal weakness. Since vitamin D deficiency is very common, and the signs are non-specific, it is important to maintain a high index of suspicion of vitamin D deficiency in patients with ...
Christian M. Girgis, Jenny E. Gunton
openaire +4 more sources