Results 241 to 250 of about 809,352 (389)
Lifespan‐Extending Endogenous Metabolites
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley +1 more source
25OH vitamin D3 in biliary atresia: a simple and under-utilised diagnostic method. [PDF]
Song F +4 more
europepmc +1 more source
ABSTRACT Background Recurrent otitis externa (OE) episodes commonly affect dogs with canine atopic dermatitis (cAD) despite ongoing cAD treatment. Objective To determine if a therapeutic diet with active ingredients targeting the skin barrier and allergy pathways reduces the incidence rate of OE.
Adrian Watson +5 more
wiley +1 more source
Vitamin D3 Improves Hypothalamic-Pituitary-Adrenal Axis Function, Immunological Responses, and Gut Dysbiosis in Sleep Desynchrony. [PDF]
Wu CW +6 more
europepmc +1 more source
DNA methyltransferase inhibitors in hematological malignancies and solid tumors
Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger +3 more
wiley +1 more source
Correction: Daily Vitamin D3 Versus Stoss Vitamin D3 for Correction of 25OHD Deficiency in Children with Inflammatory Bowel Disease, a Randomised Controlled Trial. [PDF]
O'Donnell JEM +11 more
europepmc +1 more source

