Results 121 to 130 of about 184,846 (305)
Advanced Science, EarlyView.A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang +10 more
wiley +1 more source
Iraqi Journal of Pharmaceutical SciencesThere are many causes of osteoporosis, and one of them is deficiency in vitamin D resulting from vitamin D receptor polymorphism. This polymorphism makes the bones and tissues that contain vitamin D receptors resistant to vitamin D and not getting ...
Noor Mohammed Abdulrahman +1 more
doaj +1 more source
, 2013 Darko Duplancic,1 Marijan Cesarik,2 Nikola Kolja Poljak,3 Maja Radman,4 Vedran Kovacic,5 Josipa Radic,5 Veljko Rogosic61Department of Cardiology, School of Medicine in Split, University Hospital Split, Split, Croatia; 2Department for Neurology, County ...
Rogosic V +6 more
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Advanced Science, EarlyView.HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang +10 more
wiley +1 more source
Prenatal vitamin D deficiency and brain development
, 2006 There is growing evidence that vitamin D is active in the brain but until recently there was a lack of evidence about its role during brain development. Guided by certain features of the Epidemiology of schizophrenia, we have explored the role of vitamin
Burne, Thomas +3 more
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MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes
Advanced Science, EarlyView.A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak +19 more
wiley +1 more source
Vitamin D receptor gene and exercise: influence on bone mineral density [PDF]
, 2007 The population with osteoporosis is estimated at over ten million people in Japan. The consecutive increase of the case is therefore a serious problem in our aging society.
Seiji TOGASHI +2 more
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Nucleic Acid Therapeutics for “Undruggable” Cancer Targets: Mechanisms, Challenges, and Prospects
Advanced Science, EarlyView.Nucleic acid therapeutics bypass the structural limitations of conventional drugs by targeting mRNA rather than proteins. This review examines how antisense oligonucleotides, siRNAs, miRNAs, aptamers, and mRNA vaccines intervene against historically undruggable oncoproteins including Ras, MYC, and p53, highlighting mechanistic advances, delivery ...
Feng Xu +6 more
wiley +1 more source
Advanced Science, EarlyView.Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source
Vitamin D has an aetiological role in dementias; myth or fact ? [PDF]
, 2020 This is an accepted manuscript of an article published in the International Journal of Development Research on 30/05/2020. The accepted version of the publication may differ from the final published version, accessible at https://www.journalijdr.com ...
Antoun Reyad, Ayman +2 more
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