Results 11 to 20 of about 278,205 (268)

VKORC1L1–mediated vitamin K recycling counters ferroptosis to promote endothelial repair [PDF]

Scientific Reports
Vitamin K is classically known for hepatic γ-carboxylation via VKORC1, yet accumulating evidence suggests broader redox-regulatory roles. Here, we characterize the VKORC1 paralogue VKORC1L1 as an anti-oxidative enzyme that couples the vitamin K cycle to ...
Elena Repges, Adem Aksoy, Katrin J. Czogalla-Nitsche, Andreas Zietzer, Cornelius Müller, Johannes Oldenburg, Sebastian Zimmer, Georg Nickenig, Vedat Tiyerili, Muntadher Al Zaidi   +9 more
doaj   +2 more sources

The effect of vitamin K on prothrombin time in critically ill patients: an observational registry study

Journal of Intensive Care, 2021
Background Previous studies have indicated that vitamin K deficiency is common in non-bleeding critically ill patients with slightly prolonged prothrombin time-international normalized ratio (PT-INR). It has never been investigated thoroughly whether the
Sofia Dahlberg, Ulf Schött, Thomas Kander   +2 more
doaj   +1 more source

Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis

Journal of Lipid Research, 2014
In contrast to other fat-soluble vitamins, dietary vitamin K is rapidly lost to the body resulting in comparatively low tissue stores. Deficiency is kept at bay by the ubiquity of vitamin K in the diet, synthesis by gut microflora in some species, and ...
Martin J. Shearer, Paul Newman
doaj   +1 more source

Stroke patients have lower blood levels of nutrients that are relevant for recovery: a systematic review and meta-analysis

Frontiers in Stroke, 2023
BackgroundMalnutrition is common after stroke. Stroke patients often have a suboptimal energy intake, body weight and inadequate blood nutrient levels. Nutrient insufficiencies may not be detected, but their recognition is essential to provide adequate ...
Laus M. Broersen, Sonia Guida, Aysun Cetinyurek-Yavuz, Aysun Cetinyurek-Yavuz, Nick van Wijk, Ardy van Helvoort, Ardy van Helvoort, Adina T. Michael-Titus, Mirian Lansink   +8 more
doaj   +1 more source

Gastrointestinal bleeding due to idiopathic early onset of vitamin K deficiency bleeding in a girl baby 50 min after birth: a rare case

BMC Pediatrics, 2022
Background The incidence of early-onset vitamin K deficiency bleeding (VKDB) in at-risk neonates who did not receive vitamin K supplementation varied from 6 to 12%. This case report aims to show that VKDB can occur abruptly after birth despite vitamin K1
Harapan Parlindungan Ringoringo, Katherine Richel Tambunan, Fajar Khalis Ananda, Felynawati Nawati, Yanuar Nusca Permana   +4 more
doaj   +1 more source

Vitamin K Epoxide Reductase Complex Subunit 1-Like 1 (VKORC1L1) Inhibition Induces a Proliferative and Pro-inflammatory Vascular Smooth Muscle Cell Phenotype

Frontiers in Cardiovascular Medicine, 2021
Background: Vitamin K antagonists (VKA) are known to promote adverse cardiovascular remodeling. Contrarily, vitamin K supplementation has been discussed to decelerate cardiovascular disease.
Adem Aksoy, Muntadher Al Zaidi, Elena Repges, Marc Ulrich Becher, Cornelius Müller, Johannes Oldenburg, Sebastian Zimmer, Georg Nickenig, Vedat Tiyerili   +8 more
doaj   +1 more source

Abraham Model Descriptors for Vitamin K4: Prediction of Solution, Biological and Thermodynamic Properties

Liquids, 2023
Spectrophotometric measurements were used to determine the mole fraction solubilities of vitamin K4 dissolved in cyclohexane, methylcyclohexane, 1-heptanol, 2-butanol, 2-pentanol, 2-methyl-1-butanol, 4-methyl-2-pentanol, and cyclopentanol at 298.15 K ...
Saikiran Motati, Ramya Motati, Trisha Kandi, William E. Acree   +3 more
doaj   +1 more source

Factors affecting the absorption of vitamin K-1 in vitro. [PDF]

Gut, 1976
Factors which might affect the absorption of vitamin K of dietary origin were investigated using everted small bowel sacs. Increasing the bile salt concentration to 20 mM or the addition of long chain fatty acids, monoolein, or lecithin all resulted in significant (P less than 0-05) decrease in the absorption rate of the vitamin. The addition of 2-5 mM
D, Hollander, E, Rim
openaire   +2 more sources

Vitamin K supplementation for meat quail in growth of 1 to 14 days old

Semina: Ciências Agrárias, 2015
The experiment was carried outto determine the levels of vitamin K for meat quails (Coturnixcoturnixsp) from 1 to 14 days of age. Atotal of 2200 birds were used, complete by random experimental design, with 8 treatments, 5 repetitions and 55 meat quails ...
Caroline Espejo Stanquevis, Antonio Claudio Furlan, Simara Márcia Marcato, Vittor Zancanela, Daiane Oliveira Grieser, Taynara Prestes Perine, Eline Maria Finco, Tainara Ciuffi Euzébio   +7 more
doaj   +1 more source

The association of vitamin K status with lung function and disease in a general population

ERJ Open Research, 2023
Introduction Matrix Gla protein (MGP) is an inhibitor of lung tissue calcification. The plasma level of dephosphorylated-uncarboxylated MGP (dp-ucMGP) is a biomarker of vitamin K status.
Torkil Jespersen, Freja Bach Kampmann, Thomas Meinertz Dantoft, Niklas Rye Jørgensen, Line Lund Kårhus, Flemming Madsen, Allan Linneberg, Sanne Marie Thysen   +7 more
doaj   +1 more source