Results 211 to 220 of about 278,205 (268)

Synthesis of vitamin K₁ analogs. A new class of vitamin K₁ antagonists

Canadian Journal of Chemistry, 1970
The synthesis of two analogs of vitamin K1, namely, 2-chloro (2) and 2-bromo (3) analogs, is described. The separation of cis and trans isomers of both these compounds on preparative t.l.c. is reported along with the spectral data.
J. Lowenthal, M. N. Roy Chowdhury
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Vitamin K₁ and the vitamin K analogues

Clinical Pharmacology & Therapeutics, 1961
The use of vitamin K1 and various preparations with vitamin K activity in the treatment of hypoprothrombinemic states has long been a well‐established procedure. Because the K analogues have often been popularly referred to as vitamin K, confusion has arisen regarding the relationship between these compounds and the true vitamin K. Two types of vitamin
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Vitamin K Activity and Metabolism of Vitamin K-1 Epoxide-1,4-Diol

The Journal of Nutrition, 1982
Vitamin K-1 epoxide, the major metabolite of vitamin k-1, has similar activity to vitamin K-1 in inducing prothrombin synthesis and protein carboxylation. The high activity of K-1 epoxide could be due to its conversion to vitamin K-1 hydroquinone without going through vitamin K-1. A logical intermediate in this conversion would be vitamin K-1 epoxide-1,
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Glycolipid derivatives of vitamin K1

Biochemical and Biophysical Research Communications, 1972
Abstract Incubation of vitamin K1 (phylloquinone) with rat liver smooth endoplasmic reticulum and UDP-N-acetyl glucosamine resulted in the formation of two new compounds soluble in chloroform-methanol. These two derivatives of vitamin K have been found to contain carbohydrate, phosphate, and vitamin K1.
B C, Johnson, G, Valkovich
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Vitamin K1 Prophylaxis in the Newborn

JAMA, 1961
The prophylactic use of vitamin K in the newborn has been abandoned by some physicians because of conflicting reports as to its efficacy and safety. In the present study vitamin K 1 was given either in doses of 5 mg. by mouth daily to the mother in the last month of pregnancy or in doses of 5 mg. intramuscularly to the infant at birth. A test series of
T J, VIETTI, J C, STEPHENS, K R, BENNETT
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Synthesen in der Vitamin‐K‐Reihe I. Über totalsynthetisches Vitamin K₁

Helvetica Chimica Acta, 1954
AbstractDurch Kondensation von 2‐Methyl‐1,4‐naphtohydrochinon mit synthetischem Isophytol wurde mittels Bortrifluoridätherat als Kondensationsmittel ein Vitamin K1 mit racemischer Seitenkette gewonnen. Dieses totalsynthetische racemische Vitamin K1 unterscheidet sich nur geringfügig vom Vitamin K1 mit optisch einheitlicher Phytylseitenkette.
O. Isler, K. Doebel
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Determination of the diastereomers of vitamin K₁

Journal of High Resolution Chromatography, 1981
AbstractA method is described for the gas‐chromatographic determination of the diastereomers of vitamin K1 (phylloquinone) in the form of their dihydro dimethyl ethers. The reported method of derivatization and chromatographic analysis in conjunction with optical rotation measurements are useful approaches for characterization of vitamin K1 samples ...
M. Vecchi, M. Schmid, W. Walther, F. Gerber   +3 more
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[Vitamin K 1 concentration and vitamin K-dependent clotting factors in newborn infants after intramuscular and oral administration of vitamin K 1].

Orvosi hetilap, 1990
Serum concentration of vitamin K1 and activity of vitamin-K-dependent factors II, VII, IX and X were determined before and after vitamin K1 administration in infants. The babies received vitamin K1 intramuscularly or orally. 12 hours after vitamin K1 treatment the mean concentration was increased in the groups receiving vitamin K1 intramusculary or ...
B, Goldschmidt, C, Kisrákói, E, Téglás, M, Verbényi, I, Kovács   +4 more
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Anaphylactic Shock and Vitamin K₁

Annals of Internal Medicine, 1989
Excerpt To the Editor:Vitamin K1(phytonadione) is used mainly as a corrector when there is a high risk of hemorrhage due to vitamin K deficiency.
Javier de la Rubia, Enric Grau, Isabel Montserrat, Isabel Zuazu, Antonio Payá   +4 more
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Effect of Vitamin K1 Supplementation on Vitamin K Status in Cystic Fibrosis Patients

Journal of Pediatric Gastroenterology & Nutrition, 1997
Background:Patients with cystic fibrosis are at risk for impaired vitamin K status due to fat malabsorption from pancreatic insufficiency. This study was designed to assess vitamin K status and measure the effect of vitamin K1 supplementation in cystic fibrosis patients.Methods:Eighteen outpatients participated in a crossover study to determine the ...
L T, Beker, R A, Ahrens, R J, Fink, M E, O'Brien, K W, Davidson, L J, Sokoll, J A, Sadowski   +6 more
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