Results 221 to 230 of about 289,689 (263)

Ein photoschaltbares Vitamin‐D‐Mimetikum mit agonistischer und antagonistischer Aktivität ermöglicht bidirektionale optische Kontrolle von VDR

open access: yesAngewandte Chemie, EarlyView.
Vitamin D entfaltet über die Aktivierung des ligandenabhängigen Transkriptionsfaktors Vitamin‐D‐Rezeptor (VDR) komplexe und zellspezifische biologische Wirkungen in verschiedenen Geweben. Das photoschaltbare Vitamin‐D‐Mimetikum 10 wechselt durch Belichtung zwischen VDR‐Antagonisten‐ (E) und Agonisten‐Aktivität (Z) und bietet eine bislang einzigartige ...
Xiu Ge   +11 more
wiley   +1 more source

Mass cytometry reveals complex neutrophil heterogeneity in patients with severe sepsis. [PDF]

open access: yesIntensive Care Med Exp
Lima PDA   +7 more
europepmc   +1 more source

An Agonist/Antagonist Photo‐Switchable Vitamin D Mimetic Enables Bidirectional Optical Control of VDR

open access: yesAngewandte Chemie International Edition, EarlyView.
Vitamin D exhibits complex and cell‐specific biological effects in multiple tissues via activation of the ligand‐sensing transcription factor vitamin D receptor (VDR). The photo‐switchable vitamin D mimetic 10 transitions between VDR antagonist (E) and agonist (Z) activity upon illumination and offers unprecedented bidirectional optical control over ...
Xiu Ge   +11 more
wiley   +1 more source

Sustainable Palm Oil Extraction and Trends in the Use of Green Technologies: State‐of‐the‐Art and Future Directions

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Palm oil, which is extracted from the mesocarp of the fruit of the Elaeis guineensis Jacq. palm tree, is the most widely produced vegetable oil in the world. The extraction of this substance typically utilizes the conventional pressing method, a technique that is advantageous due to its low operating cost and simplified process.
Constantino Lucas Queta   +2 more
wiley   +1 more source

Immunomodulatory and Anti-Inflammatory Effects of Ketotifen Versus Vitamin E in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized Pilot Study. [PDF]

open access: yesDrug Des Devel Ther
Aldossary KM   +12 more
europepmc   +1 more source

Degradation Mechanisms, Encapsulation‐Based Stabilization, and Analytical Detection of Vitamin A

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Vitamin A is an important lipid‐soluble micronutrient essential for vision, immune function, and overall growth and development. However, vitamin A is unstable and susceptible to environmental factors because of its conjugated structure and inherent chemical reactivity.
Latheesha Abeywardana   +5 more
wiley   +1 more source

Advances in Chitosan Nanoparticles: A Comprehensive Review of Properties, Synthesis, Characterization, Multidisciplinary Applications, and Future Perspectives

open access: yesJournal of Applied Polymer Science, EarlyView.
This review highlights the synthesis of chitosan nanoparticles from natural sources, the thorough characterization of them, and use of microscopic and spectroscopic methods. It emphasizes that it has some indispensable properties such as being non‐toxic, antimicrobial, and capable of controlled drug release.
Mariam Sohail Mansoor   +6 more
wiley   +1 more source

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