Results 61 to 70 of about 10,028,727 (294)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Comparing Major Gastrointestinal Bleeding in Patients Receiving Edoxaban Versus Warfarin After Transcatheter Aortic Valve Replacement: Results From the Randomized ENVISAGE‐TAVI AF Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Non–vitamin K oral anticoagulants are recommended over vitamin K antagonists in patients with nonvalvular atrial fibrillation (AF). However, the risk of gastrointestinal bleeding may be higher with non–vitamin K oral anticoagulants versus ...
George D. Dangas, Martin Unverdorben, Johny Nicolas, Christian Hengstenberg, Cathy Chen, Helge Möllmann, James Jin, Fayaz Shawl, Masanori Yamamoto, Shigeru Saito, Rainer Hambrecht, Anil Duggal, Nicolas M. Van Mieghem   +12 more
doaj   +1 more source

Data on incidence of bleeding in patients with atrial fibrillation and advanced liver fibrosis on treatment with vitamin K or non-vitamin K antagonist oral anticoagulants

Data in Brief, 2018
This article contains the data showing the different characteristics of atrial fibrillation (AF) patients treated with vitamin K (VKAs) or non-vitamin K antagonist oral anticoagulants (NOACs) screened for the presence of liver fibrosis (LF) and followed ...
Daniele Pastori, Gregory Y.H. Lip, Alessio Farcomeni, Francesco Del Sole, Angela Sciacqua, Francesco Perticone, Rossella Marcucci, Elisa Grifoni, Pasquale Pignatelli, Francesco Violi   +9 more
doaj   +1 more source

Vascular calcification: The price to pay for anticoagulation therapy with vitamin K-antagonists

, 2012
Vitamin K-antagonists (VKA) are the most widely used anti-thrombotic drugs with substantial efficacy in reducing risk of arterial and venous thrombosis. Several lines of evidence indicate, however, that VKA inhibit not only post-translational activation ...
Winckers, Kristien, Hackeng, Tilman M.; id_orcid, Chris P. Reutelingsperger, Leon J. Schurgers, Chatrou, Martijn L. L., Kristien Winckers, Schurgers, Leon J.; id_orcid, Reutelingsperger, Chris P. M., Tilman M. Hackeng, Martijn L.L. Chatrou   +9 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Role of vitamin K-dependent proteins in the arterial vessel wall

, 2011
Vitamin K was discovered early last century at the same time as the vitamin K-antagonists. For many years the role of vitamin K was solely ascribed to coagulation and coagulation was thought to be involved only at the venous blood side.
Chatrou, M. L. L., Reutelingsperger, C. P., C. P. Reutelingsperger, M. L. L. Chatrou, Schurgers, L. J.; id_orcid, L. J. Schurgers   +5 more
core   +1 more source

A guide to acquired vitamin K coagulophathy diagnosis and treatment: the Russian perspective

, 2021
Physicians often come across with cases of vitamin K antagonists-dependent coagulopathy for reasons such as accidental use of the vitamin K antagonists (VKA), excessive administration of prescribed anticoagulants of indirect action or not reported ...
PIVNIK, Alexander V., KODINTSEV, Vladimir V., SERGIEVICH, Alexander A., TSAROUHAS, Konstantinos, GOFITA, Eliza, TSATSAKIS, Aristidis M., Ozcagli, Eren, TSITSIMPIKOU, Christina, DOCEA, Anca Oana, CALINA, Daniela, GOLOKHVAST, Kirill S., FILATOVA, Ekaterina A., WOJCIECHOWSKI, Valery V., ARSENE, Andreea Letitia   +13 more
core   +1 more source

Facial Cosmetic Therapy Use Among Patients With Systemic Sclerosis: An Australian Cohort Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is associated with numerous facial manifestations for which patients may engage in cosmetic therapies. It is unclear how patients with SSc use these therapies. This study sought to characterize patient engagement and experiences with cosmetic therapies for SSc‐related and non‐SSc–related facial changes.
Zachary Warren, Diane Apostolopoulos, Gene‐Siew Ngian, Amanda M. Saracino, Laura Ross, Nava Ferdowsi, Jennifer Walker, Cindy Hall, Kim Griggs, Susanna Proudman, Wendy Stevens, Joanne Sahhar   +11 more
wiley   +1 more source

Self‐Sintering Ionogel Binder for Flexible, Recyclable, and Healable Printed Giant Magnetoresistive Sensors

Advanced Functional Materials, EarlyView.
ABSTRACT Electronic waste has emerged as a major environmental challenge, driven by the massive consumption and a limited lifetime of modern electronic devices, stimulating the development of sustainable electronics. Here, an all‐biomaterial gelatin‐choline‐citric acid ([Ch][CA]) ionogel is developed as an active binder to realize self‐sintered ...
Lin Guo, Xiaotao Wang, Guannan Mu, Proloy Taran Das, Igor Veremchuk, Conrad Schubert, Aaron D. Cross, Yevhen Zabila, Xuan Peng, Larysa Baraban, Denys Makarov   +10 more
wiley   +1 more source

Efficacy and Safety of Direct‐Acting Oral Anticoagulants in Atrial Fibrillation With Hypertrophic Cardiomyopathy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Patients with hypertrophic cardiomyopathy (HCM) were excluded from pivotal trials comparing the efficacy and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists.
Amro Taha, Avilash Mondal, Usman Ali Akbar, Aobo Li, Harigopal Sandhyavenu, Mohamed Alhajji, Sittinun Thangjui, Harshith Thyagaturu, Christopher Bianco, Marco Caccamo, Ahmad Masri, Sudarshan Balla   +11 more
doaj   +1 more source