Results 71 to 80 of about 10,028,727 (294)

Anticoagulation therapy and the use of non-vitamin K antagonist oral anticoagulants in the elderly

, 2017
Anticoagulation indications do not differ between elderly and younger patients. However due to the changes with ageing some anticoagulants may increase the risk of bleeding. Therefore a dose adjustment might be needed for some anticoagulant drugs.
Ongen, Zeki, Zeki Öngen
core   +1 more source

Nanoamphizymes: Self‐Assembled Amphiphilic Enzymatic Nanomaterials for High‐Performance Biocatalysis and Biosensing

Advanced Functional Materials, EarlyView.
An amphiphilic GOx nanoamphizyme was constructed by covalently introducing hydrophobic PPNI linkers onto GOx, enabling spontaneous self‐assembly into tunable nanoparticles. Mild crosslinking further stabilized the assemblies and enhanced catalytic performance and stability.
Yuan‐Hao Hsiao, Rajan Deepan Chakravarthy, Po‐Hsiang Chen, Abdelreheem Abdelfatah Saddik, Hsin‐Chieh Lin   +4 more
wiley   +1 more source

Influence of age on the prescription of vitamin K antagonists in outpatients with permanent atrial fibrillation in France.

, 2007
International audiencePURPOSE: The aim of the study was to describe the current rate and determinants of the prescription of antithrombotics in outpatients with permanent atrial fibrillation, with a pre-specified emphasis on the influence of age on the ...
Leizorovicz, A., Renseigné, Non, Cohen, Albert, Mismetti, P., Guenoun, M., Weisslinger, N.   +5 more
core   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Antithrombotic Treatment and Clinical Outcomes After Intracerebral Hemorrhage: A Retrospective Cohort Study from the Swedish Stroke Register

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background A rapid shift has occurred from vitamin K antagonists toward direct oral anticoagulants, which have a lower risk of intracerebral hemorrhage (ICH). However, effects on clinical outcomes after ICH are understudied.
Mattias Tallroth, Ruzan Udumyan, András Büki, Mia von Euler   +3 more
doaj   +1 more source

Current insights on cardiovascular and neurodegenerative relations of direct oral anticoagulants and their biotransformation [PDF]

Pharmacia
An intriguing connection explored over the years is the link between neurodegenerative diseases and thrombosis. A number of studies have focused on associations between cardiovascular events and neurodegenerative diseases such as Alzheimer’s, Parkinson’s,
Nikolina Todorova, Alexandrina Mateeva, Alexandra Savova, Magdalena Kondeva-Burdina   +3 more
doaj   +3 more sources

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Vitamin K Properties in Stroke and Alzheimer’s Disease: A Janus Bifrons in Protection and Prevention

Molecules
Vitamin K is essential for many physiological processes, including coagulation, bone metabolism, tissue calcification, and antioxidant activity.
Lorenzo Grimaldi, Rosaria A. Cavallaro, Domenico De Angelis, Andrea Fuso, Giulia Sancesario   +4 more
doaj   +1 more source

Vitamin K antagonists: impact on hospitalizations and accesses to emergency room

, 2017
The Adverse Drug Reactions (ADR) are responsible of increasing hospital admissions, prolongation of hospital stay, and emergency room (ER) visits. The aim of our study was to estimate the impact of the anticoagulant therapy with vitamin K antagonists ...
Piacentini, P., G Troiano, N Nante, P Piacentini, Nisticò, F., Dei, S., S Dei, F Nisticò, Troiano, G., Nante, N.   +9 more
core   +1 more source