Results 1 to 10 of about 67,829 (284)

The relationship between stress and vitiligo: Evaluating perceived stress and electronic medical record data.

PLoS ONE, 2020
Vitiligo is a T-cell mediated skin disorder characterized by progressive loss of skin color. In individuals genetically predisposed to the disease, various triggers contribute to the initiation of vitiligo.
Steven W Henning, Dinesh Jaishankar, Levi W Barse, Emilia R Dellacecca, Nicola Lancki, Kirsten Webb, Linda Janusek, Herbert L Mathews, Ronald N Price, I Caroline Le Poole   +9 more
doaj   +2 more sources

Exploring the Role of Adipose Tissue Dysregulation in Vitiligo Pathogenesis: A Body Composition Analysis [PDF]

Acta Dermato-Venereologica
Vitiligo is a commonly acquired pigmentary disease characterized by the progressive destruction of melanocytes. The role of adipose tissue in vitiligo remains unclear. To investigate the role of adipose tissue in the pathogenesis of vitiligo, 50 patients
XinYi Shao, Xingyu Pan, Tingqiao Chen, Ziyan Chen, Yuhao Li, Judan Zhong, Ruiyao Wang, Jun Yu, Jin Chen, Yangmei Chen   +9 more
doaj   +2 more sources

AI fusion of multisource data identifies key features of vitiligo [PDF]

Scientific Reports
Vitiligo is a skin disorder that is associated with a decreased risk of skin cancer, but it can lead to increased susceptibility to sunburn, psychological distress, and disruptions in daily life, consists of two primary subtypes: segmental and ...
Zheng Wang, Yang Xue, Zirou Liu, Chong Wang, Kaifen Xiong, Kaibin Lin, Jiarui Ou, Jianglin Zhang   +7 more
doaj   +2 more sources

The Role of Oxidative Stress in Vitiligo: An Update on Its Pathogenesis and Therapeutic Implications

Cells, 2023
Vitiligo is an autoimmune skin disorder caused by dysfunctional pigment-producing melanocytes which are attacked by immune cells. Oxidative stress is considered to play a crucial role in activating consequent autoimmune responses related to vitiligo ...
Wei-Ling Chang, Chi-Hsiang Ko
semanticscholar   +1 more source

Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the international Vitiligo Task Force—Part 2: Specific treatment recommendations

Journal of the European Academy of Dermatology and Venereology, 2023
The treatment of vitiligo can be challenging. Up‐to‐date agreed consensus recommendations on the use of topical and systemic therapies to facilitate the clinical management of vitiligo are currently lacking.
J. Seneschal, R. Speeckaert, Alain Taïeb, A. Wolkerstorfer, T. Passeron, Amit G. Pandya, Henry W. Lim, K. Ezzedine, Youwen Zhou, Flora Xiang, S. Thng, A. Tanemura, Tamio Suzuki, D. Rosmarin, M. Rodrigues, N. Raboobee, Georg Pliszewski, D. Parsad, Naoki Oiso, Paul Monteiro, J.‐M. Meurant, Nicolle Maquignon, Harvey Lui, C. Le Poole, G. Leone, Ai-Young Lee, Eric Lan, Ichiro Katayama, Richard H Huggins, S. H. Oh, John E. Harris, I. Hamzavi, Somesh Gupta, P. Grimes, Boon Kee Goh, D. Ghia, S. Esmat, V. Eleftheriadou, M. Böhm, L. Benzekri, M. Bekkenk, J. Bae, Augustin Alomar, M. Abdallah, M. Picardo, N. van Geel   +45 more
semanticscholar   +1 more source

Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the International Vitiligo Task Force Part 1: towards a new management algorithm

Journal of the European Academy of Dermatology and Venereology, 2023
The treatment of vitiligo can be challenging and depends on several factors such as the subtype, disease activity, vitiligo extent, and treatment goals. Vitiligo usually requires a long‐term approach.
N. van Geel, R. Speeckaert, Alain Taïeb, K. Ezzedine, Henry W. Lim, Amit G. Pandya, T. Passeron, A. Wolkerstorfer, M. Abdallah, A. Alomar, J. Bae, M. Bekkenk, L. Benzekri, M. Böhm, V. Eleftheriadou, S. Esmat, D. Ghia, B. Goh, P. Grimes, Somesh Gupta, I. Hamzavi, John E. Harris, S. Oh, Richard H Huggins, I. Katayama, Eric Lan, A. Lee, G. Leone, C. Le Poole, H. Lui, Nicolle Maquignon, J.‐M. Meurant, P. Monteiro, N. Oiso, D. Parsad, Georg Pliszewski, N. Raboobee, M. Rodrigues, D. Rosmarin, Tamio Suzuki, A. Tanemura, S. Thng, Flora Xiang, Youwen Zhou, M. Picardo, J. Seneschal   +45 more
semanticscholar   +1 more source

Two Phase 3, Randomized, Controlled Trials of Ruxolitinib Cream for Vitiligo.

New England Journal of Medicine, 2022
BACKGROUND Vitiligo is a chronic autoimmune disease that causes skin depigmentation. A cream formulation of ruxolitinib (an inhibitor of Janus kinase 1 and 2) resulted in repigmentation in a phase 2 trial involving adults with vitiligo.
D. Rosmarin, T. Passeron, A. Pandya, P. Grimes, John E. Harris, S. Desai, M. Lebwohl, M. Ruer-Mulard, J. Seneschal, A. Wolkerstorfer, D. Kornacki, K. Sun, K. Butler, K. Ezzedine   +13 more
semanticscholar   +1 more source

The Role of Oxidative Stress in the Pathogenesis of Vitiligo: A Culprit for Melanocyte Death

Oxidative Medicine and Cellular Longevity, 2022
Vitiligo is a common chronic acquired pigmentation disorder characterized by loss of pigmentation. Among various hypotheses proposed for the pathogenesis of vitiligo, oxidative stress-induced immune response that ultimately leads to melanocyte death ...
Y. Xuan, Yiwen Yang, L. Xiang, Chengfeng Zhang   +3 more
semanticscholar   +1 more source

Vitiligo prevalence and quality of life among adults in Europe, Japan and the USA

Journal of the European Academy of Dermatology and Venereology, 2022
Vitiligo, an autoimmune disorder characterised by skin depigmentation, is associated with reduced quality of life (QoL). Vitiligo may be under‐reported, in part because of misconceptions that it is a cosmetic disease.
K. Bibeau, A. Pandya, K. Ezzedine, H. Jones, J. Gao, A. Lindley, J. Harris   +6 more
semanticscholar   +1 more source

From zero to one: Recent advances in the pathogenesis, diagnosis, and treatment of vitiligo

Dermatologica Sinica, 2023
Vitiligo is the most common acquired pigmentary disorder and can have profound negative psychosocial impacts on patients. The disease course of vitiligo is often unpredictable, and diagnosis and treatment of vitiligo remain a challenging dermatological ...
Peng-Chieh Shen, Tsung-Fu Tsai, Yi-Jing Lai, Tzu-Li Liu, Chau Yee Ng   +4 more
doaj   +1 more source