Results 31 to 40 of about 57,061 (258)

Association between the CTLA4 +49A/G (rs231775) and CT60 (rs3087243) gene variants with vitiligo: study on a Mexican population [PDF]

Anais Brasileiros de Dermatologia, 2022
Background: Vitiligo is characterized by an autoimmune response targeting melanocytes, thus resulting in skin depigmentation. There are several genetic components involved in the development of vitiligo, of which various gene polymorphisms are currently ...
Mauricio Andrés Salinas-Santander, Víctor de Jesús Suárez-Valencia, Mayela del Ángel-Martínez, David Emmanuel Kubelis-Lopez, Natalia Aranza Zapata-Salazar, Jorge Alejandro Ocampo-Garza, Jorge Ocampo-Candiani   +6 more
doaj   +1 more source

Vitiligo: A Review [PDF]

Dermatology, 2020
Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5–2% of the population worldwide. The disease is characterized by the selective loss of melanocytes which results in typical nonscaly, chalky-white macules. In recent years, considerable progress has been made in our understanding of the pathogenesis of vitiligo which is ...
Bergqvist, Christina, Ezzedine, Khaled
openaire   +2 more sources

A case of new-onset vitiligo in a patient on tofacitinib and brief review of paradoxical presentations with other novel targeted therapies [PDF]

, 2020
With recent advancements in the understanding of vitiligo pathogenesis, Janus kinase (JAK) inhibitors have emerged as a promising new treatment modality, but their effects remain incompletely elucidated.
Alikhan, Mujahed, Jogi, Reena, Nguyen, Julie K, Patel, Anisha B, Schlichte, Megan J   +4 more
core  

Emerging Topical and Systemic JAK Inhibitors in Dermatology [PDF]

, 2019
Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders.
Ghoreschi, Kamran, Meier, Katharina, Solimani, Farzan   +2 more
core   +1 more source

Serum interleukin 15 as a marker of activity in patients with vitiligo

Journal of the Egyptian Women’s Dermatologic Society, 2021
Background Interleukin 15 (IL15) is a proinflammatory cytokine that is involved in the pathogenesis of several autoimmune and inflammatory diseases. The stability of vitiligo represents the periods of no activity of the disease, and it is crucial in ...
Ashraf Hamza, Mona Aiad, Ahmed Abdel-Bary, Eman Gouda   +3 more
doaj   +1 more source

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo [PDF]

, 2012
We previously reported a genome-wide association study (GWAS) identifying 14 susceptibility loci for generalized vitiligo. We report here a second GWAS (450 individuals with vitiligo (cases) and 3,182 controls), an independent replication study (1,440 ...
Ben, S., Bennett, D.C., Birlea, S.A., Cole, J.B., Eichner, S., Ezzedine, K., Fain, P.R., Ferrara, T.M., Gawkrodger, D.J., Gowan, K., Hartmann, A., Holland, P.J., Jin, Y., Jouary, T., Kemp, E.H., Lambert, J., Leone, G., Luiten, R.M., McCormack, W.T., Overbeck, A., Picardo, M., Riccardi, S.L., Schuler, G., Silverberg, N.B., Spritz, R.A., Taïeb, A., van der Veen, J.P.W., van Geel, N., Wallace, M.R., Weetman, A.P., Wolkerstorfer, A.   +30 more
core   +4 more sources

Vitiligo and Autoimmunity [PDF]

Medical Archives, 2013
Vitiligo is an acquired skin disorder characterized by depigmented maculae resulting from a reduction of the number and function of melanocytes. The etiopathogenesis of the disease is still unclear, but there is evidence that autoimmunity may be involved.The aim of this study was to determine the prevalence and significance of antinuclear (ANA) and ...
Tomica Jukic, Emina Kasumagic-Halilovic, Begler Begovic, Nermina Ovcina-Kurtovic, Jasenko Karamehic, Sladjana Samardzic   +5 more
openaire   +2 more sources

Safety and efficacy of fluticasone propionate in the topical treatment of skin diseases [PDF]

, 2004
Fluticasone propionate - the first carbothioate corticosteroid - has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance treatment of ...
Atsuta J, Boner AL, Bridgman A, Callen J, Delescluse J, Dooms-Goossens AE, Dykes PJ, Falcoz C, Fisher DA, Goossens A, Harding SM, Hogger P, James M, Johnson M, Johnson M, Juhlin L, Katz HI, Korting HC, Lebwohl M, Li JT, Liu XQ, Llewellyn-Jones CG, Lucky AW, McKenzie AW, McLean HM, Nurnberger FG, Phillipps GH, Roberts DT, Spencer CM, Tharp MD, Venning VA, Wilkinson SM, Wolkerstorfer A, Young MMR   +33 more
core   +1 more source

Clinical characteristics of late-onset vitiligo in an Iranian population

Dermatologica Sinica, 2012
Background: The age of onset of vitiligo is before 20 years in approximately in 50% of patients, and its incidence decreases with increasing age. In this study, our aim was to analyze the epidemiological and clinical factors of patients with late-onset ...
Iraj Esfandiarpour, Saeedeh Farajzadeh
doaj   +1 more source

Prepubertal and postpubertal vitiligo: a multivariate comparative study in 375 patients [PDF]

Anais Brasileiros de Dermatologia, 2017
: Background: The onset of vitiligo during childhood is common. Limited data exist that compare the clinical associations of prepubertal and postpubertal vitiligo in Arabs.
Huma Khurrum, Khalid M AlGhamdi
doaj   +1 more source