Results 151 to 160 of about 25,365 (278)

Vitrification in ART getting closer? /

, 2010
Background: Twenty five years after the first successful application in mammalian embryology vitrification seems to emerge now from the “new”, “experimental”, “immature” category and has become a method of choice for routine use both in domestic animals ...
G Vajita (9876857), Vajita, Gabor.
core  

Dehydration‐driven organization of metabolites into NaDES‐like assemblies in orthodox seeds

New Phytologist, EarlyView.
Summary Desiccation tolerance in plants, especially during orthodox seed dehydration, relies on compatible solute accumulation, complex molecular mechanisms, and intermolecular organizations that remain poorly understood. We combined metabolite profiling, mass spectrometry imaging, and electrospray and cold‐spray ionization mass spectrometry to ...
Youcef Haddad, Thomas Delhaye, Emmanuelle Limanton, Denis Morineau, Maëna Le Corvec, Christine Deponge, Anne Levrel, Alain Moréac, Virginie Nazabal, David Rondeau, Ludovic Paquin, Alain Bouchereau   +11 more
wiley   +1 more source

Capture of adeno‐associated viruses from clarified lysate by continuous flow ultracentrifugation: a comparative study of iodixanol and sucrose gradients

Journal of Chemical Technology &Biotechnology, Volume 101, Issue 7, Page 1384-1395, July 2026.
Abstract BACKGROUND Adeno‐Associated Virus vectors are widely used in gene therapy due to their safety and efficacy. Despite the interest in their therapeutical application, AAV purification remains a significant challenge. Density gradient ultracentrifugation using cesium chloride, sucrose, or iodixanol gradients are common methods for AAV ...
Sabrina Leigheb, Maral Rahimzadeh, Nikolaus Virgolini, Aida Tleuova, Mahbod Mousavian, Astrid Dürauer, Patricia Pereira Aguilar   +6 more
wiley   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, Volume 46, Issue 4, Page 921-944, July 2026.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Parallelized droplet vitrification for single-run vitrification of hepatocytes from an entire rat liver

: Drug discovery pipelines rely on the availability of isolated primary hepatocytes for investigating potential hepatotoxicity prior to clinical application.
Uygun, Korkut, Hassan, Madeeha, Tchir, Alexandra, Taggart, Mclean, Van Dieren, Lo\uefc, Dinicu, Antonia, Lellouch, Alexandre G., Toner, Mehmet, Sandlin, Rebecca D., Chen, Huyun, Taveras, Christopher   +10 more
core  

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

Equine Veterinary Journal, Volume 58, Issue 4, Page 970-980, July 2026.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez, Alejandro de la Fuente, Kazuki Takahashi, Hugo Monteiro, Mauricio Mendes, Stuart Meyers, Pouya Dini   +6 more
wiley   +1 more source

Research Progress on Mammalian Oocyte Vitrification: From Damage Mechanisms to Optimization Strategies. [PDF]

Animals (Basel)
Song K, Wang L, Yang F, Zhu H, Meng Q, Han X, Qiao R, Bai J, Gun S, Yu T, Li X.   +10 more
europepmc   +1 more source

Sustainable Glass Foams From Recycled Glass and Rice Husk Ash: Thermal Insulation Performance for Ceiling Applications

International Journal of Applied Glass Science, Volume 17, Issue 3, July 2026.
Glass foams were produced using recycled glass and rice husk ash as raw materials. After deep characterization, miniature masonry model tests demonstrated effective thermal insulation when applied as a ceiling lining. The study validates the technical and environmental feasibility of glass foams for sustainable insulating materials in building ...
Carlos Eduardo Keller Bertolo, Pedro Augusto Stadler, Mariana Rodrigues Padilha, Victor Duarte Trindade, Simone Dornelles Venquiaruto, Jacson Weber de Menezes, Chiara Valsecchi   +6 more
wiley   +1 more source

Effect of Niacin Supplementation During In Vitro Maturation on Fertilization Rate and Mitochondrial Competence of Vitrified and Nonvitrified Bovine Oocytes. [PDF]

Vet Med Int
Azari M, Kafi M, Eshghi D, Salehi A, Farahmand F.   +4 more
europepmc   +1 more source

Comprehensive Biophysical Profiling Evidences Self‐Oligomerization of Bacterially Expressed Pc Protein

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Polycomb (Pc), a core component of Polycomb Repressive Complex 1 (PRC1), is largely intrinsically disordered yet forms buffer‐ and concentration‐dependent higher‐order assemblies. Integrative biophysical analysis and cryo‐electron microscopy reveal dynamic, heterogeneous oligomers, whereas AlphaFold modeling suggests that structural organization is ...
Maria Zahid, Sabin Prajapati, Ghazaleh Alamdari, Kai Tittmann, Selin Kara   +4 more
wiley   +1 more source