Results 111 to 120 of about 7,461 (205)
Identification of CYP2C9 and VKORC1 polymorphisms in Iranian patients who are under warfarin therapy
International Journal of Hematology-Oncology and Stem Cell Research, 2016 Background: Although catalytic properties of different genetic polymorphisms of VKORC1 and CYP2C9 products have been identified, there is limited study available regarding warfarin dose requirement in Iranian patient population.
Behzad Poopak +5 more
doaj
Pharmacogenetics – individualized treatment of genetic disorders [PDF]
, 2011 Farmakogenetika je grana znanosti koja proučava povezanost genotipa sa različitom reakcijom na terapiju nekim lijekovima. Potencijal farmakogenetike je velik jer će dobiveni rezultati istraživanja omogućiti i olakšati individualizirano liječenje ...
Biluš, Mirna
core +2 more sources
Рациональная фармакотерапия в кардиологии, 2016 Aim. To evaluate treatment adherence and prevalence of CYP2C9 and VKORC1 gene mutations in patients with atrial fibrillation (AF) and provide rationale of choice for oral anticoagulation therapy.Material and methods.
Yu. P. Skirdenko +3 more
doaj +1 more source
Migrationsbarrieren gegen Wühlmäuse – Erfahrungen aus 3 Jahren Praxiseinsatz [PDF]
, 2006 In der landwirtschaftlichen Praxis wird die Wühlmausbekämpfung vorrangig mit Fraßködern, Fallen und Begasungsgeräten durchgeführt. Um die Besiedlung wühlmausfreier Flächen zu verhindern werden seit 2002 Migrationsbarrieren in der obstbaulichen Praxis ...
Malevez, J., Pelz, H.-J., Walther, B.
core
Novel VKORC1 mutations associated with warfarin sensitivity.
Cardiovascular therapeutics, 2011 Warfarin is widely used anticoagulant drug for the prophylaxis and treatment of venous and arterial thromboembolic disorders and exerts its anticoagulant effect by inhibiting the vitamin K epoxide reductase. To determine the impact of genetic variants of the vitamin K epoxide reductase complex subunit 1 gene (VKORC1) on the anticoagulant response to ...
Shadi, Baniasadi +6 more
openaire +1 more source
Association of polymorphic variants of the gene VKORC 1 with ischemic atherothrombotic stroke [PDF]
, 2016 Annually Stroke affects 16 million people and causes the death of nearly 6 million. 88% of all strokes account for ischemic stroke genesis.
Harbuzova, Yelizaveta Antonivna +2 more
core
Polymorphism of the CYP2C9 and VKORC1 genes: a comment [PDF]
Jornal Vascular Brasileiro, 2021 Rujittika Mungmunpuntipantip +2 more
openaire +4 more sources
PLoS ONE, 2019 In response to strong selection, new mutations can arise quickly and sweep through populations, particularly, if survival and reproduction depend on certain allele copies for adaptation to rapidly changing environments, like resistance against deadly ...
Matthias Stöck +7 more
doaj +1 more source
How Can We Move Clinical Genomics Beyond the Hype? [PDF]
, 2011 Examines the debate over increased use of genetic testing, due in part to lax regulation, and its consequences: wasteful spending, patient harm, and health system challenges.
Michael L. Millenson
core
'Drug'-induced pneumonitis associated with CYP and VKORC1 variants.
The Bulletin of contemporary clinical medicine, 2010 The presence of CYP variant genotypes appears to be a substantial susceptibility risk factor in the development of drug-induced pulmonary adverse events. We hypothesized that in some patients these serious complications may be associated with the presence of variant alleles in combination with illicit drug use.
WIJNEN P.A.H.M., Bekers, O., Drent, M.
openaire +2 more sources