Background: For the first time, we determined and analyzed frequency of the most important variant alleles of CYP2C9, CYP2C19, CYP3A5 and VKORC1 in Kosovo‟s population. Methods: Determination of genetic polymorphism was conducted in 234 nonrelated Kosovars and genotyping was conducted by Real-Time PCR. Results: Allele frequencies of CYP 2C9*2 and 2C9*3
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Design and validation of a clinical whole genome sequencing-based assay for patient screening in a large healthcare system. [PDF]
Wagner JT +16 more
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GENOTIPIZACIJA VKORC1, CYP4F2, CYP2C9 NA VZORCU SPLOŠNE POPULACIJE
Namen diplomske naloge je določiti genotipe specifičnih enonukleotidnih polimorfizmov tarčnih genov, ki so odgovorni za višji ali nižji začetni odmerek varfarina. To so VKORC1-1639G>A, CYP2C92-430C>T, CYP2C93-1075A>C, CYP4F2-132C>T. Varfarin je učinkovina, oralni antikoagulant, ki se predpisuje bolnikom z pljučno embolijo, globoko vensko trombozo ...
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The curious family of cytochrome P450 4F fatty acid ω-hydroxylases: recent developments in their function and relevance for human health. [PDF]
Alves Chagas BC +3 more
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Recommendations for (Pharmaco)Genetic Sampling in Patients Following Allogeneic Hematopoietic Stem Cell Transplantation. [PDF]
Bokma A +8 more
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Application of rapid genotyping of Warfarin individualized pharmacogenetic variants in Warfarin therapy. [PDF]
Huang D +10 more
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Widespread anticoagulant resistance in house mice (Mus musculus musculus) linked to the Tyr139Phe mutation in the Czech Republic. [PDF]
Frankova M +3 more
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Regarding: the role of fat-soluble vitamins A, D, E, and K in osteoporosis: mechanisms, interactions, and evidence. [PDF]
Chen S.
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An Exploratory Pharmacogenetic Pilot Study of Two Reverse Transcriptase Inhibitors, Tenofovir Alafenamide Fumarate and Tenofovir Disoproxil Fumarate. [PDF]
Murrell DE +8 more
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Pharmacodynamic Modeling of Warfarin Dosing Algorithm for Cardiovascular Patients in Indonesia: A Tailored Method to Anticoagulation Therapy. [PDF]
Putriana NA +4 more
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