VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression: involvement of the VLDL receptor [PDF]
The potential role of the very low density lipoprotein (VLDL) receptor in mediating VLDL-induced plasminogen activator inhibitor-1 (PAI-1) expression was studied in vitro.
Lennart Nilsson+7 more
doaj +7 more sources
Visibly Linear Dynamic Logic [PDF]
We introduce Visibly Linear Dynamic Logic (VLDL), which extends Linear Temporal Logic (LTL) by temporal operators that are guarded by visibly pushdown languages over finite words. In VLDL one can, e.g., express that a function resets a variable to its original value after its execution, even in the presence of an unbounded number of intermediate ...
Weinert, Alexander, Zimmermann, Martin
arxiv +8 more sources
Plasma clearance and biodistribution of oxidatively modified 99mTc-ß-VLDL in rabbits [PDF]
The biodistribution and removal from plasma (measured as fractional clearance rate, FCR, per hour) of native and oxidatively modified 99mtechnetium-labeled ß-very low density lipoprotein (99mTc-ß-VLDL) were investigated in hypercholesterolemic (HC) and ...
E.L. Silva+3 more
doaj +2 more sources
Lipolytic remnants of human VLDL produced in vitro: effect of HDL levels in the lipolysis mixtures on the apoCs to apoE ratio and metabolic properties of VLDL core remnants [PDF]
To determine the role of high-density lipoprotein (HDL) as an acceptor of lipolytic surface remnants of very low density lipoprotein (VLDL) in the metabolism of VLDL core remnants, we examined the effect of HDL levels in the VLDL lipolysis mixture on 1 ...
Byung Hong Chung, Nassrin Dashti
doaj +2 more sources
Measuring VLDL-triglyceride turnover in humans using ex vivo-prepared VLDL tracer [PDF]
There has been more interest in VLDL-triglyceride (TG) kinetics during the last decade. Unfortunately, robust measurement methods are elaborate and not readily available.
Lars C. Gormsen+2 more
doaj +6 more sources
Expression of the VLDL Receptor in Endothelial Cells [PDF]
Abstract In this article we describe the cellular distribution of the very low density lipoprotein receptor (VLDLR), a transmembrane protein that is expressed at high concentrations in skeletal muscle, heart, adipose tissue, and brain but in only trace amounts in the liver.
Kathleen Wyne+3 more
openaire +4 more sources
Effects of dietary fish oil on serum lipids and VLDL kinetics in hyperlipidemic apolipoprotein E*3-Leiden transgenic mice [PDF]
Studying the effects of dietary fish oil on VLDL metabolism in humans is subject to both large intra- and interindividual variability. In the present study we therefore used hyperlipidemic apolipoprotein (APO) E*3-Leiden mice, which have impaired ...
Bart J.M. van Vlijmen+5 more
doaj +2 more sources
ApoA-II expression in CETP transgenic mice increases VLDL production and impairs VLDL clearance [PDF]
Apolipoprotein (apo)A-II is a major high density lipoprotein (HDL) protein; however, its role in lipoprotein metabolism is largely unknown. Transgenic (Tg) mice that overexpress human apoA-II present functional lecithin: cholesterol acyltransferase deficiency, HDL deficiency, hypertriglyceridemia and, when fed an atherogenic diet, increased non-HDL ...
Francesc González-Sastre+5 more
openaire +5 more sources
Reproducibility of stable isotope-labeled tracer measures of VLDL-triglyceride and VLDL-apolipoprotein B-100 kinetics [PDF]
To gain insight into the mechanisms regulating plasma lipid homeostasis, FFA, VLDL-triglyceride (TG), and VLDL-apolipoprotein B-100 (apoB-100) kinetics are commonly assessed using stable isotope-labeled tracer methods.
Magkos Faidon+2 more
doaj +4 more sources
VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation [PDF]
Our previous work indicated that apolipoprotein (apo) E4 assumes a more expanded conformation in the postprandial period. The postprandial state is characterized by increased VLDL lipolysis.
Sarada D. Tetali+9 more
doaj +4 more sources