Results 231 to 240 of about 59,863 (274)

Relationship of VLDL receptor and LPL in metabolism of VLDL by macrophage

Journal of Tongji Medical University, 1991
Macrophages were incubated with 125I-VLDL for 5 h in presence or absence of lipoprotein lipase (LPL) inhibitor, benzene boronic acid (BBA). Both the uptake and degradation of 125I-VLDL by macrophages were saturable, and the uptake and degradation curves were virtually identical. When macrophages were incubated with 125I-VLDL for 10 h in presence of BBA,
Y Z, Deng, Z C, Feng, H X, Wang, W G, Jiang, Y Q, Zhong, C F, Wang   +5 more
openaire   +2 more sources

Up-regulation of VLDL receptor expression and its signaling pathway induced by VLDL and β-VLDL

Journal of Huazhong University of Science and Technology [Medical Sciences], 2009
Very low density lipoprotein receptor (VLDLR) is thought to participate in the pathogenesis of atherosclerosis induced by VLDL and beta-VLDL. The present study was undertaken to elucidate the effects of VLDL and beta-VLDL on VLDLR expression and its signaling pathway. RAW264.7 cells were incubated with VLDL and beta-VLDL.
Zhiguo, Liu, He, Li, Yinghong, Li, Yan, Wang, Yiqiang, Zong, Youmei, Feng, Zongchen, Feng, Yaozu, Deng, Shen, Qu   +8 more
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Hepatic denervation impairs the assembly and secretion of VLDL‐TAG

Cell Biochemistry and Function, 2008
VLDL secretion is a regulated process that depends on the availability of lipids, apoB and MTP. Our aim was to investigate the effect of liver denervation upon the secretion of VLDL and the expression of proteins involved in this process. Denervation was
Marilia Seelaender
exaly   +2 more sources

Role of lipoprotein lipase separated from VLDL during VLDL catabolism

Biochemical and Biophysical Research Communications, 1982
Abstract Lipoprotein lipase (LPL) which is associated with very low density lipoprotein (VLDL) separated from the VLDL-LPL complex during hydrolysis of triglyceride in the presence of HDL in vitro. When further VLDL was added to the mixture, the separated LPL became associated with the freshly added VLDL and hydrolyzed its triglyceride. These results
N, Matsuoka, K, Shirai, Y, Saito, A, Kumagai   +3 more
openaire   +2 more sources

IDL, VLDL, chylomicrons and atherosclerosis

European Journal of Epidemiology, 1992
In humans with the lipoprotein lipase deficiency disorder large amounts of chylomicrons and large very low-density lipoprotein (VLDL) accumulate in plasma. In spite of this, atherosclerosis does not seem to develop at an accelerated rate, suggesting that these lipoproteins do not promote atherogenesis.
B G, Nordestgaard, A, Tybjaerg-Hansen
openaire   +2 more sources

Role of VLDL receptor in atherogenesis

Current Opinion in Lipidology, 2021
Purpose of review My group previously discovered and characterized the rabbit and human VLDL receptors. For more than 30 years, I have focused on research regarding the functions of VLDL receptors in the fields of lipoprotein metabolism and atherogenesis.
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Estimation of VLDL cholesterol in hyperlipidemia

Clinica Chimica Acta, 1985
Lipoprotein data from 10947 fasting blood samples drawn between 1968 and 1982 in the Molecular Disease Branch at the National Institutes of Health were used to test the generalizability of estimating very low density lipoprotein cholesterol (VLDL-C) from plasma triglyceride (TG).
P W, Wilson, L A, Zech, R E, Gregg, E J, Schaefer, J M, Hoeg, D L, Sprecher, H B, Brewer   +6 more
openaire   +2 more sources

Metabolism of VLDL and LDL subclasses

Current Opinion in Lipidology, 1994
The recognition of lipoprotein heterogeneity has given new depth to our understanding of lipoprotein metabolism and the role of plasma triglyceride as a determinant of lipoprotein subclass distribution and potential atherogenicity. It has also provided insight into the relationship between exogenous and endogenous lipid transport pathways, the roles of
B A, Griffin, C J, Packard
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Metabolism of n-VLDL and β-VLDL in peritoneal macrophages from diabetic mice

Journal of Tongji Medical University, 1989
Peritoneal macrophages were harvested from both healthy mice and mice with diabetes induced by intravenous injection of streptozotocin. After incubation with normal plasma very low density lipoprotein (n-VLDL) from swine for 24 h, the content of triglyceride (TG) in macrophages from diabetic mice was higher than that in the controls, and it was the ...
G, Gheng, Z L, Wei, W G, Jiang, J, Zhang, C R, An, Z C, Feng   +5 more
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Hyperinsulinemia and VLDL Kinetics

1993
The most frequent lipoprotein abnormality in diabetes mellitus is hypertriglyceridemia. The frequency of hypercholesterolemia is not very different from that found in the nondiabetic population.1,2 In those diabetic individuals who are grossly insulin deficient, the hypertriglyceridemia is due to an accumulation of chylomicrons, the primary ...
openaire   +2 more sources