Results 21 to 30 of about 43,360 (234)

Plasma lipoprotein metabolism in lean and in fat chickens produced by divergent selection for plasma very low density lipoprotein concentration.

Journal of Lipid Research, 1989
Plasma lipoprotein metabolism was studied in vivo in two lines of chickens produced by selection for high and low plasma very low density lipoprotein (VLDL) concentration.
H Griffin, F Acamovic, K Guo, J Peddie
doaj   +1 more source

Oxidized type IV hypertriglyceridemic VLDL-remnants cause greater macrophage cholesteryl ester accumulation than oxidized LDL

Journal of Lipid Research, 1998
We have previously shown that very low density lipoproteins (VLDL, Sf 60–400) from subjects with type IV hyperlipoproteinemia (HTG-VLDL) will induce appreciable cholesteryl ester accumulation in cultured macrophages (J774A.1).
Stewart C. Whitman, Cynthia G. Sawyez, David B. Miller, Bernard M. Wolfe, Murray W. Huff   +4 more
doaj   +1 more source

Systemic Review to Explore the Effect of Dyslipidaemia and Metabolic Function in Coronary Heart Disease with Type 2 Diabetes Mellitus: In Tertiary Care Center

Journal of Pharmacy and Bioallied Sciences
Metabolic dyslipidemia (high triglyceride) and low high-density lipoprotein cholesterol (HDL-C) are highly prevalent in type 2 diabetes mellitus (T2DM).
Akansha Singh, Ranjit S. Ambad, Roshan K. Jha   +2 more
doaj   +1 more source

Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans

Journal of Lipid Research, 2003
Subjects with high plasma cholesterol levels exhibit a high production of VLDL apolipoprotein B-100 (apoB-100), suggesting that cholesterol is a mediator for VLDL production.
Berthil H.C.M.T. Prinsen, Johannes A. Romijn, Peter H. Bisschop, Martina M.J. de Barse, P.Hugh R. Barrett, Marie¨tte Ackermans, Ruud Berger, Ton J. Rabelink, Monique G.M. de Sain-van der Velden   +8 more
doaj   +1 more source

Adipocytokines and VLDL Metabolism [PDF]

Diabetes, 2005
We investigated the relationship of plasma adipocytokine concentrations with VLDL apolipoprotein B (apoB)-100 kinetics in men. Plasma adiponectin, leptin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) concentrations were measured using enzyme immunoassays and insulin resistance by homeostasis model assessment (HOMA) score in 41 ...
Theodore W.K. Ng, Gerald F. Watts, Maryam S. Farvid, Dick C. Chan, P. Hugh R. Barrett   +4 more
openaire   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Lipolytic remnants of human VLDL produced in vitro: effect of HDL levels in the lipolysis mixtures on the apoCs to apoE ratio and metabolic properties of VLDL core remnants

Journal of Lipid Research, 2000
To determine the role of high-density lipoprotein (HDL) as an acceptor of lipolytic surface remnants of very low density lipoprotein (VLDL) in the metabolism of VLDL core remnants, we examined the effect of HDL levels in the VLDL lipolysis mixture on 1 ...
Byung Hong Chung, Nassrin Dashti
doaj   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway.

Journal of Lipid Research, 1996
Very low density lipoproteins (VLDL) are produced in the liver and contain apolipoprotein (apo) B-100 and endogenous lipids. By contrast, ingestion of fat leads to formation of chylomicrons containing apoB-48 secreted from the intestine. In this study, a
J Bjorkegren, C J Packard, A Hamsten, D Bedford, M Caslake, L Foster, J Shepherd, P Stewart, F Karpe   +8 more
doaj   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source