Results 21 to 30 of about 106,533 (346)

Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion

Hepatology, EarlyView., 2022
The role of SMLR1 in lipid metabolism (high fat + cholesterol diet in mice) Abstract Background and Aims The assembly and secretion of VLDL from the liver, a pathway that affects hepatic and plasma lipids, remains incompletely understood. We set out to identify players in the VLDL biogenesis pathway by identifying genes that are co‐expressed with the ...
Willemien van Zwol, Antoine Rimbert, Justina C. Wolters, Marieke Smit, Vincent W. Bloks, Niels J. Kloosterhuis, Nicolette C. A. Huijkman, Mirjam H. Koster, Umesh Tharehalli, Simon M. de Neck, Colin Bournez, Marceline M. Fuh, Jeroen Kuipers, Sujith Rajan, Alain de Bruin, Henry N. Ginsberg, Gerard J. P. van Westen, M. Mahmood Hussain, Ludger Scheja, Joerg Heeren, Philip Zimmerman, Bart van de Sluis, Jan Albert Kuivenhoven   +22 more
wiley   +1 more source

Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development

Theranostics, 2020
Rationale: Men and postmenopausal women are more prone to developing non-alcoholic fatty liver disease/steatohepatitis (NAFLD/NASH) than premenopausal women.
Meng Yang, Qingli Liu, Tongling Huang, Wenjuan Tan, Linbing Qu, Tianke Chen, H. Pan, Ling Chen, Jinsong Liu, Chi-wai Wong, W. Lu, Min Guan   +11 more
semanticscholar   +1 more source

Study of lipid profile for psoriatic patients in AL-Anbar governorate. [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2014
Psoriasis is a chronic inflammatory skin condition which affects approximately 1-3% of the world's population (1). It appears as red plaques covered with silvery scale that flakes away from the skin.Psoriatic plaques are often found on the elbows, scalp ...
Wajeeh Y. Mohammed, Abdullah S. Al-Hasan, Ausama A. Faisal   +2 more
doaj   +1 more source

Dietary yolk supplementation decreases rates of yolk deposition in Japanese quail

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 339, Issue 1, Page 63-73, January 1, 2023., 2023
Dietary supplementation with egg yolk decreases the rate of yolk deposition in quail. Quail with high body condition indices deposit yolk more slowly. Abstract Generation of egg yolk by birds requires the synthesis and deposition of large amounts of protein and lipid, and is often accompanied by the incorporation of additional physiological mediators ...
Kristen J. Navara, Kylie Graden, Mary T. Mendonça   +2 more
wiley   +1 more source

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation. [PDF]

, 2012
ObjectivePostprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury.
Altman, Robin, Budamagunta, Madhu S, den Hartigh, Laura J, Hutchinson, Romobia, Lagerstedt, Jens O, Petrlova, Jitka, Rutledge, John C, Tetali, Sarada D, Voss, John C   +8 more
core   +7 more sources

The role of pulses in improving human health: A review

Legume Science, Volume 4, Issue 4, December 2022., 2022
Abstract Public health concerns are discussed so frequently that it is beginning to cause desensitization. And yet, rates of chronic disease remain alarmingly high worldwide—or are even increasing. Primary prevention is essential to reverse these trends.
Chelsea Didinger, Henry J. Thompson
wiley   +1 more source

Intracellular transports and atherogenesis

Frontiers in Bioscience-Landmark, 2020
There is a great progress in understanding the cellular and molecular aspects of atherosclerosis, which is one of the leading causes of death. Yet, there are questions regarding the cellular and metabolic mechanisms that lead to atherogenesis.
Alexander A. Mirоnоv, Irina S. Sesorova, Ivan D. Dimov, Natalia R. Karelina, Galina V. Beznoussenko   +4 more
doaj   +1 more source

Could Duodenal Molecular Mechanisms be Involved in the Hypocholesterolemic Effect of Silicon Used as Functional Ingredient in Late‐Stage Type 2 Diabetes Mellitus?

Molecular Nutrition &Food Research, Volume 66, Issue 24, December 2022., 2022
Duodenal mucosa in early‐stage type 2 diabetes mellitus (ED), late‐stage type 2 diabetes mellitus injected with streptozotocin‐nicotinamide (STZ/NAD) (LD) and treated‐silicon LD (LD‐Si) groups. Silicon partially reversed LD group alterations: decreased absorptive area and acyl‐Coenzyme A:cholesterol acyltransferase 2 (ACAT2) levels, and increased ...
Marina Hernández‐Martín, Aránzazu Bocanegra, Rocío Redondo‐Castillejo, Adrián Macho‐González, Francisco J. Sánchez‐Muniz, Juana Benedí, Sara Bastida, Rosa A. García‐Fernández, Alba Garcimartín, M. Elvira López‐Oliva   +9 more
wiley   +1 more source

Using total plasma triacylglycerol to assess hepatic de novo lipogenesis as an alternative to VLDL triacylglycerol

Upsala Journal of Medical Sciences, 2020
Background: Hepatic de novo lipogenesis (DNL) is ideally measured in very low-density lipoprotein (VLDL)-triacylglycerol (TAG). In the fasting state, the majority of plasma TAG typically represents VLDL-TAG; however, the merits of measuring DNL in total ...
Leanne Hodson, Sion A. Parry, Thomas Cornfield, Catriona Charlton, Wee Suan Low, Charlotte J. Green, Fredrik Rosqvist   +6 more
doaj   +1 more source

Relation of the size and intracellular sorting of apoB to the formation of VLDL 1 and VLDL 2 [PDF]

Journal of Lipid Research, 2005
In this study, we tested the hypothesis that two separate pathways, the two-step process and an apolipoprotein B (apoB) size-dependent lipidation process, give rise to different lipoproteins. Expression of apoB-100 and C-terminally truncated forms of apoB-100 in McA-RH7777 cells demonstrated that VLDL particles can be assembled by apoB size-dependent ...
Caroline Beck, Pia Stillemark-Billton, Jan Borén, Sven-Olof Olofsson   +3 more
openaire   +4 more sources