Results 81 to 90 of about 106,533 (346)
Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study [PDF]
, 2000 The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an ...
Cobbe, S. +7 more
core +1 more source
Enhanced Separation of Extracellular Vesicles Using Capillary Isotachophoresis With Spacer Compounds
ELECTROPHORESIS, EarlyView.ABSTRACT Extracellular vesicles (EVs) are pivotal in numerous physiological and pathological processes, such as immune responses, viral pathogenesis, pregnancy, cardiovascular diseases, and cancer progression. Their capacity to influence complex intracellular pathways highlights their therapeutic potential in addressing various conditions, including ...
Milan Pieter Paul de Putter +4 more
wiley +1 more source
PLoS ONE, 2012 Objective In addition to improve glucose intolerance, recent studies suggest that glucagon-like peptide-1 (GLP-1) receptor agonism also decreases triglyceride (TG) levels. The aim of this study was to evaluate the effect of GLP-1 receptor agonism on very-
E. Parlevliet +11 more
semanticscholar +1 more source
Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets
Food Safety and Health, EarlyView.Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar +5 more
wiley +1 more source
Human Plasma Very Low-Density Lipoproteins Are Stabilized by Electrostatic Interactions and Destabilized by Acidic pH [PDF]
, 2011 Very low-density lipoproteins (VLDL) are precursors of low-density lipoproteins (LDL, or “bad cholesterol”). Factors affecting structural integrity of VLDL are important for their metabolism.
Guha, Madhumita, Gursky, Olga
core +3 more sources
Journal of Lipid Research, 2012 Regulation of hepatic very low density lipoprotein (VLDL) assembly and maturation is crucial in controlling lipid homeostasis and in the development of metabolic disorders, including obesity, hepatic steatosis, and insulin resistance.
Xuanhe Li +5 more
semanticscholar +1 more source
Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders. [PDF]
, 2016 Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular disease.
Mahley, Robert W
core +1 more source
Adrenal cell aldosterone production is stimulated by very-low-density lipoprotein (VLDL).
Endocrinology, 2012 Very low-density lipoproteins (VLDL) are a class of large lipoprotein synthesized in the liver. The key function of VLDL, in vivo, is to carry triglyceride from the liver to adipose tissue.
Yewei Xing +5 more
semanticscholar +1 more source
Mature VLDL Particles Exit the Golgi in Distinct Post‐Golgi VLDL Vesicles
The FASEB Journal, 2013 Post‐Golgi transport of VLDL is crucial for maintaining normal triacylglycerol (TAG) homeostasis of hepatocytes, however, nothing is known about the exit of VLDLs from the Golgi. To study this important process, we established an in vitro Golgi‐budding assay to examine the formation of Golgi‐derived VLDL vesicles using hepatic Golgi containing [3H]TAG ...
Shadab A. Siddiqi +2 more
openaire +1 more source
Circulation Research, 2012 Rationale: Dysregulation of hepatic triglyceride (TG)-rich very low-density lipoproteins (VLDL-TG) in obesity and type 2 diabetes contributes to the dyslipidemia that leads to cardiovascular morbidity.
J. Yue +4 more
semanticscholar +1 more source