Results 131 to 140 of about 314,110 (197)

Biophysical Mechanism of Anesthetics [PDF]

open access: yes, 2014
I was awarded a MEG in 2008 (with support continuing through 2009) for the project entitled “Biophysical Mechanism of Anesthetics.” The goals of the project were to measure the impact of volatile general anesthetics (isoflurane, sevoflurane, and ...
Busath, David
core  

Coverage Generosity of Novel Antirheumatic Drugs in Medicare Advantage and Stand‐Alone Part D Plans

open access: yesArthritis &Rheumatology, Volume 78, Issue 10, Page 2171-2178, October 2026.
Objective We examine coverage of self‐administered disease‐modifying antirheumatic drugs (DMARDs) in Medicare Part D. Methods Using 2022–2026 Part D formulary data, we assessed coverage of the following DMARD classes that treat relapsed rheumatoid arthritis (RA): tumor necrosis factor (TNF) inhibitors, T cell costimulatory modulator, interleukin‐6 (IL ...
Youngmin Kwon   +2 more
wiley   +1 more source

Volatile anesthetics and cardiac function

open access: yes, 2006
All volatile anesthetics have been shown to induce a dose-dependent decrease in myocardial contractility and cardiac loading conditions. These depressant effects decrease myocardial oxygen demand and may, therefore, have a beneficial role on the ...
de Hert, Stefan G.
core  

A flexible suite of programs for modelling the cortex with a mean-field scheme [PDF]

open access: yes, 2007
The cerebral cortex contains many neurons. The neuron is part of the nervous system and it receives and transmits the electrical signals. These signals are significant to a human's behaviour.
Chang, Yuan-Kuei
core  

Anesthetic Management and Perioperative Outcome of Emergency Laparotomy in a Patient With Advanced Motor Neurone Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
Schematic summary of the perioperative management and clinical course of emergency laparotomy in a patient with advanced motor neurone disease (MND). ABSTRACT Motor neurone disease (MND) presents significant perioperative challenges due to progressive respiratory muscle weakness, bulbar dysfunction, autonomic instability, and altered sensitivity to ...
Sherif Elmahgoub   +2 more
wiley   +1 more source

Explore the Mechanism of Xiaoyaosan for Treatment of Bipolar Disorder Based on Network Pharmacology, Experimental Validation and Molecular Docking

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This study evaluates Xiaoyaosan (XYS) for bipolar disorder (BD) using network pharmacology and experimental validation. Molecular docking reveals interactions between active XYS compounds and potential core targets. Animal experiments confirm XYS alleviates BD‐like behaviors in mice by suppressing core targets, elucidating its multi‐target mechanism ...
Man Chen   +10 more
wiley   +1 more source

Comparable clinical outcomes and redislocation rates after isolated medial patellofemoral ligament reconstruction in patients with and without borderline anatomical risk factors for patellar instability

open access: yesJournal of Experimental Orthopaedics, Volume 13, Issue 4, October 2026.
Abstract Purpose The purpose of this study was to compare mid‐ to long‐term clinical outcomes and redislocation rates after isolated medial patellofemoral ligament (MPFL) reconstruction in patients with and without borderline anatomical risk factors. It was hypothesized that isolated MPFL reconstruction would provide comparable outcomes regardless of ...
Alessio Maione   +11 more
wiley   +1 more source

An observational laboratory study to evaluate an anesthetic gas adsorber without anesthetic gas scavenging system

open access: yesBMC Anesthesiology
Background Volatile anesthetics are known to be potent greenhouse gases and a significant source of per-and polyfluoroalkyl substances (PFAS) “forever chemical” pollution.
Katja Nickel   +8 more
doaj   +1 more source

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