Medicina, 2022 Most patients suffering from neoplastic diseases will at some point during their illness be approached surgically. Surgery itself may be unfortunately responsible for tumor proliferation and metastatic spread.
John Michael Bonvini
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BMC Anesthesiology, 2018 Background This study aimed to determine whether the use of desflurane (DES) anesthesia combined with bispectral index (BIS) monitoring and warming is effective in reducing anesthesia-controlled operating room time (ACT) in patients undergoing lengthy ...
Hong Yu, Lu Zhang, Ye Ma, Hai Yu
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Regional knockdown of NDUFS4 implicates a thalamocortical circuit mediating anesthetic sensitivity. [PDF]
PLoS ONE, 2017 Knockout of the mitochondrial complex I protein, NDUFS4, profoundly increases sensitivity of mice to volatile anesthetics. In mice carrying an Ndufs4lox/lox gene, adeno-associated virus expressing Cre recombinase was injected into regions of the brain ...
Renjini Ramadasan-Nair +5 more
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SNARE proteins as molecular masters of interneuronal communication [PDF]
, 2010 In the beginning of the 20th century the groundbreaking work\ud of Ramon y Cajal firmly established the neuron doctrine, according to which neurons are the basic structural and functional units of the nervous system. Von Weldeyer coined the term “neuron”
Georgiev, Danko D., Glazebrook, James F.
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Inhibition of firefly luciferase by general anesthetics: effect on in vitro and in vivo bioluminescence imaging. [PDF]
PLoS ONE, 2012 UNLABELLED: Bioluminescence imaging is routinely performed in anesthetized mice. Often isoflurane anesthesia is used because of its ease of use and fast induction/recovery.
Marleen Keyaerts +7 more
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Volatile anesthetics alter protein stability
Toxicology Letters, 1998 1. We have used differential scanning calorimetry to measure the halothane induced change in stability of five lipid-free proteins in aqueous solution. 2. The temperature at peak heat capacity (Tm) as the sample is heated provides a measure of stability. 3.
J W, Tanner +2 more
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USE OF INHALANT ANESTHETICS IN THREE SNAKE SPECIES [PDF]
, 2000 Different snake species respond differently to various anesthetic agents. Hence, an anesthetic procedure developed for one species cannot necessarily be safely transferred to another species.
Blouin-Demers, Gabriel +4 more
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Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]
, 2015 Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana +5 more
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High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]
, 2018 BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E. +12 more
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Sevoflurane Pre-conditioning Ameliorates Diabetic Myocardial Ischemia/Reperfusion Injury Via Differential Regulation of p38 and ERK. [PDF]
, 2020 Diabetes mellitus (DM) significantly increases myocardial ischemia/reperfusion (MI/R) injury. During DM, cardioprotection induced by conventional pre-conditioning (PreCon) is decreased due to impaired AMP-activated protein kinase (AMPK) signaling.
Cao, Jimin +11 more
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