Results 91 to 100 of about 170,636 (275)

The Importance of Metal‐Organic Framework Linker Atoms for CO2 Reduction: A DFT Study

Advanced Science, EarlyView.
Using DFT, we examine the role of linker atoms in CO2 reduction on copper‐based metal organic frameworks (Cu MOFs). Our calculations reveal that linker atoms may serve as both CO2 and H‐shuttling sites and suggest linker electrostatics as a descriptor for linker activity. ABSTRACT Although the metal within the secondary building unit of a metal‐organic
Ugochukwu Nwosu, Samira Siahrostami
wiley   +1 more source

Volcanic Eruptions Reorganize Climate Teleconnections: Detection via Riemannian Covariance Fingerprinting

Geophysical Research Letters
Standard detection and attribution of volcanic forcing targets spatial temperature anomalies. We show that the covariance structure of climate variability carries an independent volcanic fingerprint.
Sloan Austermann
doaj   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Soil modulation of Quaternary glacial-interglacial cycles

Geoderma
Sinusoidal Milankovitch orbital variations do not match the sawtooth pattern of descent into glaciation followed by abrupt termination to greenhouse interglacials seen in records of marine shale, speleothems, and ice cores.
Gregory J. Retallack
doaj   +1 more source

A timescale analysis of the Northern Hemisphere temperature response to volcanic and solar forcing [PDF]

Climate of the Past, 2005
The Northern Hemisphere temperature response to volcanic and solar forcing in the time interval 1000–1850 AD is studied using first a set of simulations with an intermediate-complexity climate model, driven by reconstructed forcings.
S. L. Weber
doaj  

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Hunga Tonga–Hunga Ha′apai Volcano Impact Model Observation Comparison (HTHH-MOC) project: experiment protocol and model descriptions [PDF]

Geoscientific Model Development
The 2022 Hunga volcanic eruption injected a significant amount of water vapor and a moderate amount of sulfur dioxide into the stratosphere, causing observable responses in the climate system.
Y. Zhu, Y. Zhu, H. Akiyoshi, V. Aquila, E. Asher, E. Asher, E. M. Bednarz, E. M. Bednarz, S. Bekki, C. Brühl, A. H. Butler, P. Case, S. Chabrillat, G. Chiodo, G. Chiodo, M. Clyne, M. Clyne, P. R. Colarco, P. R. Colarco, S. Dhomse, S. Dhomse, L. Falletti, E. Fleming, E. Fleming, B. Johnson, A. Jörimann, A. Jörimann, A. Jörimann, M. Kovilakam, G. Koren, A. Kuchar, N. Lebas, Q. Liang, C.-C. Liu, G. Mann, G. Mann, M. Manyin, M. Manyin, M. Marchand, O. Morgenstern, O. Morgenstern, O. Morgenstern, P. Newman, L. D. Oman, F. F. Østerstrøm, F. F. Østerstrøm, F. F. Østerstrøm, Y. Peng, D. Plummer, I. Quaglia, W. Randel, S. Rémy, T. Sekiya, S. Steenrod, S. Steenrod, T. Sukhodolov, S. Tilmes, K. Tsigaridis, K. Tsigaridis, R. Ueyama, D. Visioni, X. Wang, S. Watanabe, S. Watanabe, Y. Yamashita, P. Yu, W. Yu, J. Zhang, Z. Zhuo   +68 more
doaj   +1 more source

Warfare, Shmittah – and Volcanic Forcing

Journal of Ancient Judaism
Abstract The importance to Jewish history and identity of the events of the 160s BCE cannot be overstated: the Maccabean Revolt against Seleucid rule laid the political groundwork for the emergence of the independent kingdom of Judea and set its ideological direction. Among the critical episodes of that decade mentioned in narrative sources are two
openaire   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source