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Voltage-dependent anion-selective channel 1 (VDAC1)—a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane

The International Journal of Biochemistry & Cell Biology, 2005
The eukaryotic porin or voltage-dependent anion-selective channel (VDAC1) is a pore-forming protein discovered twenty five years ago in the mitochondrial outer membrane. Its gene in eukaryotes is known, but its tertiary structure has never been solved.
A. LAWEN   +5 more
openaire   +2 more sources

Endosomes: another extra-mitochondrial location of type-1 porin/voltage-dependent anion-selective channels (VDAC)

Pfl�gers Archiv European Journal of Physiology, 1998
Endocytotic vesicles (EV) isolated from rat renal cortex were subjected to SDS-polyacrylamide gel electrophoresis and Western blotting. A monoclonal antibody against human type-1 porin (31 kDa) detected a strong band of 31 kDa. The same antibody has been used as the primary antibody in indirect immunocytochemistry. Light microscopy of cryostat sections
Reymann, S.   +4 more
openaire   +3 more sources

Identification of voltage-dependent anion-selective channel protein 1 as a freezability biomarker in chicken spermatozoa

International Journal of Biological Macromolecules
The sperm freezability during cryopreservation varies widely in chicken breeds and individuals, however, the underlying mechanisms are especially less examined. Comparative 4D label-free quantitative proteomic analysis of four high-freezability (HF) and four low-freezability (LF) Beijing-You chickens identified 42 differentially expressed proteins ...
Yunhe, Zong   +8 more
openaire   +2 more sources

LvHemB1, a novel cationic antimicrobial peptide derived from the hemocyanin of Litopenaeus vannamei, induces cancer cell death by targeting mitochondrial voltage-dependent anion channel 1

Cell Biology and Toxicology, 2021
Shangjie Liu   +8 more
semanticscholar   +1 more source

Mutation of K234 and K236 in the Voltage-Dependent Anion Channel 1 Impairs Its Insertion into the Mitochondrial Outer Membrane

Journal of Bioenergetics and Biomembranes, 1999
Previous in vitro studies indicated that mutation of both K234 and K236 to arginine, glutamine, or glutamic acid impaired the ability of the voltage-dependent anion channel (VDAC1) to insert into the outer membrane of the mitochondria (Smith et al. 1995). These same mutants were expressed in a strain of Saccharomyces cerevisiae with a disruption in the
R, Angeles   +4 more
openaire   +2 more sources

Structure, gating and interactions of the voltage-dependent anion channel

European Biophysics Journal, 2021
Eszter E Najbauer   +2 more
exaly  

Expression of voltage-dependent anion channels in endometrial cancer and its potential prognostic significance

Tumor Biology, 2020
Paweł Jóźwiak   +2 more
exaly  

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