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Identification of voltage-dependent anion-selective channel protein 1 as a freezability biomarker in chicken spermatozoa

International Journal of Biological Macromolecules
The sperm freezability during cryopreservation varies widely in chicken breeds and individuals, however, the underlying mechanisms are especially less examined. Comparative 4D label-free quantitative proteomic analysis of four high-freezability (HF) and four low-freezability (LF) Beijing-You chickens identified 42 differentially expressed proteins ...
Yunhe, Zong   +8 more
openaire   +2 more sources

Mutation of K234 and K236 in the Voltage-Dependent Anion Channel 1 Impairs Its Insertion into the Mitochondrial Outer Membrane

Journal of Bioenergetics and Biomembranes, 1999
Previous in vitro studies indicated that mutation of both K234 and K236 to arginine, glutamine, or glutamic acid impaired the ability of the voltage-dependent anion channel (VDAC1) to insert into the outer membrane of the mitochondria (Smith et al. 1995). These same mutants were expressed in a strain of Saccharomyces cerevisiae with a disruption in the
R, Angeles   +4 more
openaire   +2 more sources

Pentenediol-Type Compounds Specifically Bind to Voltage-Dependent Anion Channel 1 in Saccharomyces cerevisiae Mitochondria

Biochemistry, 2019
Voltage-dependent anion channel 1 (VDAC1) situated in the outer mitochondrial membrane regulates the transfer of various metabolites and is a key player in mitochondria-mediated apoptosis. Although many small chemicals that modulate the functions of VDAC1 have been reported to date, most, if not all, of them cannot be regarded as specific reagents due ...
Yufu Unten   +8 more
openaire   +2 more sources

Voltage-dependent anion channel 1 mediates mitochondrial fission and glucose metabolic reprogramming in response to ionizing radiation

Science of The Total Environment
The ionizing radiation (IR) represents a formidable challenge as an environmental factor to mitochondria, leading to disrupt cellular energy metabolism and posing health risks. Although the deleterious impacts of IR on mitochondrial function are recognized, the specific molecular targets remain incompletely elucidated.
Ying, Xie   +6 more
openaire   +2 more sources

Expression of voltage-dependent anion channels in endometrial cancer and its potential prognostic significance

Tumor Biology, 2020
Katarzyna M Wojcik-Krowiranda   +2 more
exaly  

Voltage-dependent anion channel in mammalian spermatozoa

Biochemical and Biophysical Research Communications, 2010
Bianjiang Liu
exaly  

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