Results 101 to 110 of about 116,855 (342)

Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels [PDF]

, 2017
Large conductance Ca(2+)-activated K(+) channels (BK channels) gate open in response to both membrane voltage and intracellular Ca(2+). The channel is formed by a central pore-gate domain (PGD), which spans the membrane, plus transmembrane voltage ...
Adams, Adelman, Alvarez, Atkinson, Bao, Bao, Barrett, Behrens, Braun, Brayden, Brelidze, Brelidze, Budelli, Butler, Cox, Cui, Cui, Ferguson, Guohui Zhang, Hite, Hite, Horrigan, Horrigan, Hu, Hudspeth, Hudspeth, Jianmin Cui, Jingyi Shi, Karl L. Magleby, Kelli McFarland, Lancaster, Latorre, Lawrence Salkoff, Lee, Lee, Li, Lingle, Long, Marty, Meera, Meera, Meredith, Nimigean, Niu, Orio, Pallotta, Petersen, Robitaille, Rothberg, Schreiber, Shen, Shi, Silberberg, Sun, Sweet, Tao, Tseng-Crank, Wallner, Wei, Wellman, Wu, Wu, Xia, Xia, Xia, Yakang Jin, Yang, Yang, Yang, Yang, Yanyan Geng, Yuan, Yuan, Zhang, Zhang   +74 more
core   +3 more sources

Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems

Advanced Functional Materials, EarlyView.
MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley   +1 more source

β Subunits of Voltage-Gated Calcium Channels [PDF]

Journal of Bioenergetics and Biomembranes, 2003
Calcium channel beta subunits have marked effects on the trafficking and on several of the biophysical properties of all high voltage activated calcium channels. In this article I shall review information on the different genes, on the structure of the beta subunits, and on their differential expression and post-translational modification.
openaire   +2 more sources

Sensitized Triplet Exciton Generation in Nanostructured Polymer Scintillators: Toward Improved γ/Neutron Discrimination

Advanced Functional Materials, EarlyView.
Rapid γ/neutron discrimination through PSD is achieved in liquid droplet containing nanostructured polymeric scintillator where a TTA‐active dye is dissolved. The inclusion of a properly selected and dosed sensitizer metalated porphyrin enhances discrimination sensitivity and speed by doubling the density of annihilating triplets and increasing the ...
Luca Pollice, Xueqian Hu, Letizia G. Tedoldi, Andrea Erroi, Davide Rigamonti, Marco Tardocchi, Davide Bortot, Andrea Pola, Christoph Weder, Angelo Monguzzi   +9 more
wiley   +1 more source

Structural bases of inhibitory mechanism of CaV1.2 channel inhibitors

Nature Communications
The voltage-gated calcium channel CaV1.2 is essential for cardiac and vessel smooth muscle contractility and brain function. Accumulating evidence demonstrates that malfunctions of CaV1.2 are involved in brain and heart diseases.
Yiqing Wei, Zhuoya Yu, Lili Wang, Xiaojing Li, Na Li, Qinru Bai, Yuhang Wang, Renjie Li, Yufei Meng, Hao Xu, Xianping Wang, Yanli Dong, Zhuo Huang, Xuejun Cai Zhang, Yan Zhao   +14 more
doaj   +1 more source

Molecular and functional characterization of voltage-gated sodium channels in human sperm

Reproductive Biology and Endocrinology, 2009
Background We have investigated the expression of voltage-gated sodium channels in human spermatozoa and characterized their role in sperm motility. Methods Freshly ejaculated semen was collected from thirty normozoospermic human donors, with each donor ...
Cejudo-Román Antonio, Gallardo-Castro Manuel, Fernández-Sánchez Manuel, Ravina Cristina G, Pinto Francisco M, Candenas Luz   +5 more
doaj   +1 more source

Levels of Ca\u3csub\u3ev\u3c/sub\u3e1.2 L-Type Ca\u3csup\u3e2+\u3c/sup\u3e Channels Peak in the First Two Weeks in Rat Hippocampus Whereas Ca\u3csub\u3ev\u3c/sub\u3e1.3 Channels Steadily Increase through Development [PDF]

, 2012
Influx of calcium through voltage-dependent channels regulates processes throughout the nervous system. Specifically, influx through L-type channels plays a variety of roles in early neuronal development and is commonly modulated by G-protein-coupled ...
Ingraham, Nicholas E., Kramer, Audra A., Mynlieff, Michelle, Sharpe, Emily J.   +3 more
core   +1 more source

Structural and Chemical Engineering of Sub‐Nanochannel Membranes Toward Ion Selectivity

Advanced Functional Materials, EarlyView.
This review summarizes recent advances in structural and chemical engineering of sub‐nanochannels for ion selectivity. We first introduce fundamental ion transport mechanisms within sub‐nanochannels, followed by strategies to tune pore size, geometry, and surface functionalities, categorized into charge‐based, ion‐recognition, hydrophilic bonding, and ...
Yuyu Su, Huacheng Zhang, Tamar L. Greaves, Qi Han, Weiwei Lei, Dan Liu   +5 more
wiley   +1 more source

Proestrus Differentially Regulates Expression of Ion Channel and Calcium Homeostasis Genes in GnRH Neurons of Mice

Frontiers in Molecular Neuroscience, 2019
In proestrus, the changing gonadal hormone milieu alters the physiological properties of GnRH neurons and contributes to the development of the GnRH surge.
Csaba Vastagh, Norbert Solymosi, Imre Farkas, Zsolt Liposits, Zsolt Liposits   +4 more
doaj   +1 more source

Fast Track to the Overdoped Regime of Superconducting YBa2Cu3O7‐δ Thin Films via Electrochemical Oxidation

Advanced Functional Materials, EarlyView.
Overdoping high temperature superconductors, such as YBa2Cu3O7‐δ (YBCO), is expected to maxime the critical current density by optimising the condensation energy for a given defect landscape, providing new thrust for the development of fusion enabling coated conductors. Here, precise oxygen control is achieved via an electrochemical method allowing for
Alexander Stangl, Aiswarya Kethamkuzhi, Hervé Roussel, Cornelia Pop, Xavier Obradors, Teresa Puig, Mónica Burriel, Arnaud Badel   +7 more
wiley   +1 more source