Results 111 to 120 of about 116,855 (342)
康复学报, 2019 Objective:To observe the effect of electroacupuncture at Shuigou acupoint on the recovery of neurological function to explore the mechanism of the L-type voltage-gated calcium channels in hippocampal CA1 region of middle cerebral artery occlusion(MCAO ...
Da LONG, Ling CHEN, Yu YAO, Mingan ZENG
doaj
Case Reports in Neurological Medicine, 2015 Inherited channelopathies are a heterogeneous group of disorders resulting from dysfunction of ion channels in cellular membranes. They may manifest as diseases affecting skeletal muscle contraction, the conduction system of the heart, nervous system ...
Muthiah Subramanian +2 more
doaj +1 more source
The tarantula toxin psalmotoxin 1 inhibits acid-sensing ion channel (ASIC) 1a by increasing its apparent H+ affinity [PDF]
, 2005 Acid-sensing ion channels (ASICs) are ion channels activated by extracellular protons. They are involved in higher brain functions and perception of pain, taste, and mechanical stimuli.
Chen, Xuanmao
core +1 more source
An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification
Advanced Healthcare Materials, EarlyView.We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese +10 more
wiley +1 more source
Structural modeling of ion channels using AlphaFold2, RoseTTAFold2, and ESMFold
ChannelsIon channels play key roles in human physiology and are important targets in drug discovery. The atomic-scale structures of ion channels provide invaluable insights into a fundamental understanding of the molecular mechanisms of channel gating and ...
Phuong Tran Nguyen +5 more
doaj +1 more source
FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel [PDF]
, 2001 Hair cells in mouse cochlear cultures are selectively labeled by brief exposure to FM1-43, a styryl dye used to study endocytosis and exocytosis. Real-time confocal microscopy indicates that dye entry is rapid and via the apical surface.
Gale, J.E. +4 more
core +1 more source
Retinoschisin, a New Binding Partner for L-type Voltage-gated Calcium Channels in the Retina [PDF]
, 2008 Liheng Shi +4 more
openalex +1 more source
ω-Phonetoxins inhibit voltage-gated calcium Ca V 2.2 ion channel splice isoforms of dorsal root ganglia [PDF]
, 2023 Célio José de Castro +4 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni +15 more
wiley +1 more source
Voltage-gated calcium channels: Structure, permeability and inactivation properties
BIO Web of Conferences, 2016 Our group has been interested in the structure and function of voltage-gated Ca2+ channels since many years. We have tried to combine molecular cloning, site-directed mutagenesis, heterologous expression, electrophysiological recordings and fluorescence ...
Charnet Pierre +5 more
doaj +1 more source