Results 161 to 170 of about 116,855 (342)

The Role of Voltage-Gated Calcium Channels in Basal Ganglia Neurodegenerative Disorders. [PDF]

Curr Neuropharmacol, 2023
Correa BHM, Moreira CR, Hildebrand ME, Vieira LB.   +3 more
europepmc   +1 more source

Biophysical and Pharmacological Properties of Voltage-gated Calcium Channels in Osteoblastic MC3T3-E1 Cells.

, 2002
Mutsuhito Tatamiya, Hitoshi Hotokezaka, Noriaki Yoshida, Kazuhide Kobayashi, Toshihide Sato, Yukio Okada   +5 more
openalex   +2 more sources

Cisplatin alters the function and expression of N-type voltage-gated calcium channels in the absence of morphological damage of sensory neurons [PDF]

, 2017
Markus Leo, Linda-Isabell Schmitt, Holger Jastrow, Jürgen Thomale, Christoph Kleinschnitz, Tim Hagenacker   +5 more
openalex   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

Advanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater, Savvas Kourtis, Camilla Reiter Elbæk, Lorena Espinar, Carolina Toro‐Márquez, Albert Coll‐Manzano, Alfredo Smiriglia, Laura García‐López, Laura Wiegand, Maria Guirola, Frédéric Fontaine, Andrea Morandi, André C. Müller, Sara Sdelci   +13 more
wiley   +1 more source

Retracted: Upregulation of N-Type Voltage-Gated Calcium Channels Induces Neuropathic Pain in Experimental Autoimmune Neuritis. [PDF]

Evid Based Complement Alternat Med, 2023
And Alternative Medicine EC.
europepmc   +1 more source

Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of CaV2.1 voltage-gated calcium channels

, 2012
Edgar Garza-López, Alejandro Sandoval, Ricardo González‐Ramírez, María A. Gandini, Arn van den Maagdenberg, Michel De Waard, Ricardo Felix   +6 more
openalex   +2 more sources

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Diverse organization of voltage-gated calcium channels at presynaptic active zones. [PDF]

Front Synaptic Neurosci, 2022
Zhang W, Jiang HH, Luo F.
europepmc   +1 more source

Molecular Interactions in the Voltage Sensor Controlling Gating Properties of Ca V Calcium Channels [PDF]

, 2015
Petronel Tuluc, Vladimir Yarov‐Yarovoy, Bruno Benedetti, Bernhard E. Flucher   +3 more
openalex   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source