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[Voltage-gated calcium channels].
Uspekhi fiziologicheskikh nauk, 2006The article concentrates on representatives of voltage-gated calcium ion-channels that are present in practically all cells. Considered are the activation and inactivation processes of calcium channels and their molecular mechanisms. The review represents modem classification of voltage-gated calcium channels, draws parallels with the earlier ...
A G, Kamkin +3 more
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Therapeutic Potential of Voltage Gated Calcium Channels
Mini-Reviews in Medicinal Chemistry, 2008Voltage-gated Calcium channels (VGCCs) play important roles in neurotransmitter release, excitation-contraction coupling, hormone secretion, and a variety of other physiological processes. Currently, there exist ion channel therapeutics for anxiety, epilepsy, hypertension, insomnia and pain.
C Gopi, Mohan, Tamanna, Gandhi
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MODIFIED VOLTAGE-GATED CALCIUM CHANNELS
2004The present invention relates to modified voltage-gated calcium (CaV ) channels. Furthermore, the invention provides nucleic acid sequences to generate modified CaV channels as well as isolated CaV channel proteins or subunits. The present invention further provides cells or animal models expressing the modified CaV channels.
FRIEDRICH ALEXANDER UNI VERSIT +3 more
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Voltage-gated calcium channels and Parkinson's disease
Pharmacology & Therapeutics, 2012A complex interaction of environmental, genetic and epigenetic factors combine with ageing to cause the most prevalent of movement disorders Parkinson's disease. Current pharmacological treatments only tackle the symptoms and do not stop progression of the disease or reverse the neurodegenerative process.
Hurley, Michael J., Dexter, David T.
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Targeting voltage-gated calcium channels in neurological and psychiatric diseases
Nature Reviews Drug Discovery, 2015Gerald W. Zamponi
exaly
Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels
Annual Review of Pharmacology and Toxicology, 2020Michael J Lenaeus, Tamer M Gamal El-Din
exaly

