Results 181 to 190 of about 115,275 (296)

Effects of natural Lithium and Lithium isotopes on voltage gated sodium channel activity in SH-SY5Y and IPSC derived cortical neurons. [PDF]

Sci Rep
Bukhteeva I, Livingstone JD, Singh K, Pavlov EV, Beazely MA, Gingras MJP, Leonenko Z.   +6 more
europepmc   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

L-quebrachitol Modulates the Anti-convulsant Effects of Carbamazepine Possibly Through Voltage-gated Sodium Channel Blocking Mechanism in Chicks: In Vivo and In Silico Studies. [PDF]

Brain Behav
Asrafi A, Aslam M, Alkhathami AG, Hossain MS, Rakib IH, Al Hasan MS, Nun FK, Amin MF, Islam MT.   +8 more
europepmc   +1 more source

MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control. [PDF]

Proc Natl Acad Sci U S A, 2023
Heiland M, Connolly NMC, Mamad O, Nguyen NT, Kesavan JC, Langa E, Fanning K, Sanfeliu A, Yan Y, Su J, Venø MT, Costard LS, Neubert V, Engel T, Hill TDM, Freiman TM, Mahesh A, Tiwari VK, Rosenow F, Bauer S, Kjems J, Morris G, Henshall DC.   +22 more
europepmc   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

The Plant Alkaloid Harmaline Blocks the Voltage-Gated Sodium Channel Na_v1.7: A Study Using an Automated Patch-Clamp. [PDF]

Int J Mol Sci
Eisfeld J, Schumacher M, Krautwald M, Wierschke S, Qin L, Fechtali T, Brinkmeier H.   +6 more
europepmc   +1 more source

The voltage-gated sodium channel, para, limits Anopheles coluzzii vector competence in a microbiota dependent manner. [PDF]

Sci Rep, 2023
Nardini L, Brito-Fravallo E, Campagne P, Pain A, Genève C, Vernick KD, Mitri C.   +6 more
europepmc   +1 more source

Irradiated Tumor Cell‐Derived Microparticles Activate Systemic Anti‐Tumor Immunity via the STING/NLRP3/GSDMD Axis in Neutrophils

Advanced Science, EarlyView.
Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu, Jiacheng Wang, Mengjie Che, Zheng Yang, Jingshu Meng, Xiao Yang, Yue Deng, Zhiyuan Zhou, Yijun Wang, Wenwen Wei, Zhanjie Zhang, Bian Wu, You Qin, Kunyu Yang, Honglin Jin, Fang Huang, Yajie Sun, Lu Wen, Chao Wan   +18 more
wiley   +1 more source

Mutations in the voltage-gated sodium channel associated with permethrin resistance in Rhipicephalus linnaei populations in Thailand. [PDF]

Sci Rep
Takhampunya R, Ngonsawan W, Longkunan A, Phasomkusolsil S, Promsathaporn S, Tippayachai B, Sakolvaree J, Mann AN, Lindroth EJ.   +8 more
europepmc   +1 more source

Beta-subunit-eliminated eHAP expression (BeHAPe) cells reveal subunit regulation of the cardiac voltage-gated sodium channel. [PDF]

J Biol Chem, 2023
Minard AY, Clark CJ, Ahern CA, Piper RC.
europepmc   +1 more source