Results 91 to 100 of about 107,111 (187)

Dual receptor-sites reveal the structural basis for hyperactivation of sodium channels by poison-dart toxin batrachotoxin

Nature Communications
The poison dart toxin batrachotoxin is exceptional for its high potency and toxicity, and for its multifaceted modification of the function of voltage-gated sodium channels.
Lige Tonggu, Goragot Wisedchaisri, Tamer M. Gamal El-Din, Michael J. Lenaeus, Matthew M. Logan, Tatsuya Toma, Justin Du Bois, Ning Zheng, William A. Catterall   +8 more
doaj   +1 more source

Phosphoinositide regulation of voltage-gated sodium channels. [PDF]

J Gen Physiol, 2023
Short B.
europepmc   +1 more source

Trifunctional Saxitoxin Conjugates for Covalent Labeling of Voltage-Gated Sodium Channels. [PDF]

Chembiochem, 2023
Finkelstein DS, Du Bois J.
europepmc   +1 more source

Molecular Dynamics Simulations of Ion Permeation in Human Voltage-Gated Sodium Channels. [PDF]

J Chem Theory Comput, 2023
Alberini G, Alexis Paz S, Corradi B, Abrams CF, Benfenati F, Maragliano L.   +5 more
europepmc   +1 more source

VGSC-DB: an online database of voltage-gated sodium channels. [PDF]

J Cheminform, 2022
Wang G, Yu J, Du H, Shen C, Zhang X, Liu Y, Zhang Y, Cao D, Pan P, Hou T.   +9 more
europepmc   +1 more source

Voltage gated sodium channels as therapeutic targets for chronic pain

Journal of Pain Research, 2019
Renee Siu Yu Ma,1 Kayani Kayani,1 Danniella Whyte-Oshodi,1 Aiyesha Whyte-Oshodi,2 Nitish Nachiappan,3 Shaene Gnanarajah,1 Raihan Mohammed1 1Department of Medicine, University of Cambridge, Cambridge, UK; 2Faculty of Medicine,
Ma RSY, Kayani K, Whyte-Oshodi D, Whyte-Oshodi A, Nachiappan N, Gnanarajah S, Mohammed R   +6 more
doaj  

Action potential conduction in the mouse and rat vagus nerve is dependent on multiple voltage-gated sodium channels (Na_V1s). [PDF]

J Neurophysiol, 2023
Nair SS, Pavelkova N, Murphy CM, Kollarik M, Taylor-Clark TE.   +4 more
europepmc   +1 more source

Block of Voltage-Gated Sodium Channels by Aripiprazole in a State-Dependent Manner. [PDF]

Int J Mol Sci, 2022
Föhr KJ, Rapp M, Fauler M, Zimmer T, Jungwirth B, Messerer DAC.   +5 more
europepmc   +1 more source

Alternative splicing in voltage-gated sodium channels: mechanisms, regulatory networks and therapeutic implications. [PDF]

Ann Med
Qiu J, Wu P, Zhang Y, Li Y, Xia C, Peng S, Sun J.   +6 more
europepmc   +1 more source

Domain- and state-specific shape of the electric field tunes voltage sensing in voltage-gated sodium channels. [PDF]

Biophys J, 2023
Kostritskii AY, Machtens JP.
europepmc   +1 more source