Results 241 to 250 of about 108,977 (287)

Voltage-Gated Sodium Channels and Pain

Current Drug Target -CNS & Neurological Disorders, 2004
Voltage-gated sodium channels are highly specialized molecular transducers that play a significant role in the creation and transmission of electrical activity throughout the neuraxis. These ion channels are fundamentally involved in sensory neuron physiology and pathophysiology; a complete but localized suspension of their normal function can prevent ...
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Voltage gated sodium channels

RCSB Protein Data Bank, 2020
Tomas Koltai, Stephan J. Reshkin, Salvador Harguindey   +2 more
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Voltage Gated Sodium Channels

2014
Overview: biophysical properties and structure of sodium channels.- The voltage sensor module in sodium channels.- Slow inactivation of Na+ channels.- Regulation/modulation of sensory neuron sodium channels.- Ubiquitylation of voltage-gated sodium channels.- Probing gating mechanisms of sodium channel using pore blockers.- Animal toxins influence ...
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Voltage-Gated Sodium Channels in Neurological Disorders

CNS & Neurological Disorders - Drug Targets, 2008
Voltage-gated sodium channels play an essential biophysical role in many excitable cells such as neurons. They transmit electrical signals through action potential (AP) generation and propagation in the peripheral (PNS) and central nervous systems (CNS). Each sodium channel is formed by one alpha-subunit and one or more beta-subunits.
Mohamed, Chahine, Aurélien, Chatelier, Olga, Babich, Johannes J, Krupp   +3 more
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Voltage-gated sodium channels as therapeutic targets

Drug Discovery Today, 2000
Voltage-gated sodium channels (VGSCs) play a central role in the generation and propagation of action potentials in neurons and other cells. VGSC modulators have their origins in empirical pharmacology and are being used as local anaesthetics, antiarrhythmics, analgesics and antiepileptics, and for other disorders.
, Clare, , Tate, , Nobbs, , Romanos
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Diversity of Mammalian Voltage‐Gated Sodium Channels

Annals of the New York Academy of Sciences, 1999
ABSTRACT: A variety of different isoforms of mammalian voltage‐gated sodium channels have been identified. These channels can be classified into three different types. Eight type 1 isoforms have been identified in the CNS, PNS, skeletal muscle, and heart.
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Voltage-Gated Sodium Channels

2007
Dorothy A. Hanck, Harry A. Fozzard
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Artificial channels for confined mass transport at the sub-nanometre scale

Nature Reviews Materials, 2021
Jie Shen, Gong-Ping Liu, Yu Han
exaly  

Fundamentals, status and promise of sodium-based batteries

Nature Reviews Materials, 2021
Robert E Usiskin, Yaxiang Lu, Jelena Popovic   +2 more
exaly  

Recycling of sodium-ion batteries

Nature Reviews Materials, 2023
Yun Zhao, Naser Tavajohi Hassan Kiadeh
exaly