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Von Willebrand disease diagnosis: from complexity to simplicity [PDF]

open access: yesResearch and Practice in Thrombosis and Haemostasis
Von Willebrand disease (VWD) is a complex disorder in terms of both its pathophysiology and treatment. The broad recognition and treatment of patients with VWD is often hindered by the complicated diagnostic process.
Quentin Van Thillo, Cédric Hermans
doaj   +2 more sources

Genetic variants in VWF exon 26 and their implications for type 1 Von Willebrand disease in a Saudi Arabian population [PDF]

open access: yesOpen Life Sciences
Von Willebrand disease (VWD) is one of the most common bleeding disorders, stemming from irregularities in the Von Willebrand factor (VWF). Globally, type 1 VWD (VWD1) is the most prevalent form, characterized by decreased levels of VWF in the blood ...
Alzahrani Faisal M.   +8 more
doaj   +2 more sources

Prevalence of iron deficiency in patients with mild to moderate bleeding disorders and bleeding disorder of unknown cause [PDF]

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Iron deficiency (ID) and ID anemia (IDA) are often caused by chronic bleeding, especially heavy menstrual bleeding, and thus may occur at a high frequency in patients with mild to moderate bleeding disorders (MBDs).
Tim Dreier   +8 more
doaj   +2 more sources

Oral post-surgical complications in patients with hemophilia and von Willebrand disease [PDF]

open access: yesHematology, Transfusion and Cell Therapy
Objective: To determine the prevalence of post-surgical complications in patients with hemophilia and von Willebrand disease. Methods: A prospective, cross-sectional study with descriptive and exploratory data analysis was conducted at the outpatient ...
Luisa Catarina Porfirio de Sousa   +3 more
doaj   +2 more sources

Rictor maintains endothelial integrity under shear stress

open access: yesFrontiers in Cell and Developmental Biology, 2022
Background: Endothelial injury induced by low shear stress (LSS) is an initiating factor in the pathogenesis of various cardiovascular diseases, including atherosclerosis, hypertension, and thrombotic diseases.
Hui Li   +9 more
doaj   +1 more source

Case report: A case of acquired von Willebrand syndrome as onset clinical presentation of systemic lupus erythematosus manifested as epistaxis and pulmonary hemorrhage

open access: yesFrontiers in Pediatrics, 2022
BackgroundAcquired von Willebrand syndrome (AVWS) is a less common bleeding disorder, primarily manifested as mild to moderate mucocutaneous bleeding and laboratory tests are similar to hereditary von Willebrand disease (VWD).
Songmi Wang   +6 more
doaj   +1 more source

von Willebrand's disease [PDF]

open access: yesEuropean Journal of Haematology, 1975
The common inheritable hemorrhagic disorder, von Willebrand's disease, has been known for only about 50 yr. During these years it has been well established that the cause of the disease is a deficiency of a plasma protein with remarkable biological properties. Future research should focus on details of the molecular structure of this protein.
L, Holmberg, I M, Nilsson
openaire   +3 more sources

Pseudotumor of the Maxillary Sinus in a Child with Von Willebrand Disease [PDF]

open access: yesIranian Journal of Otorhinolaryngology, 2022
Introduction:Mandibular pseudotumors, also known as blood cysts, are rare complications which occur more frequently in patients with an associated bleeding disorder such as hemophilia.Case Report: We present a case of a 2-year and 6-month-old patient ...
Martha Gutierrez Perez   +4 more
doaj   +1 more source

Influence of von Willebrand factor on common pathophysiological mechanisms of cerebrovascular diseases and multiple sclerosis

open access: yesНеврология, нейропсихиатрия, психосоматика, 2021
Endothelial dysfunction is a universal pathological mechanism underlying or contributing to the development/progression of many diseases, including cerebrovascular disease and multiple sclerosis.
I. A. Koltsov   +5 more
doaj   +1 more source

Von Willebrand Disease

open access: yesPediatrics In Review, 2014
Von Willebrand disease (VWD) is an inherited defect of blood coagulation that may cause excessive bleeding.
Stacy, Cooper, Clifford, Takemoto
openaire   +4 more sources

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