Results 91 to 100 of about 160,288 (338)

Hemangiosarcoma of the third eyelid in a horse [PDF]

, 2009
A 12-year-old Belgian Warmblood mare was referred to the equine clinic of the Faculty of Veterinary Medicine (Ghent University) for a mass on the third eyelid of the right eye. The horse had been having a recurrent red-tinged ocular discharge for several
Chiers, Koen, Ducatelle, Richard, Gasthuys, Frank, Vandecasteele, Maximilien, Wegge, Beatrice   +4 more
core  

Circulating inflammatory and hemostatic biomarkers are associated with risk of myocardial infarction and coronary death, but not angina pectoris, in older men [PDF]

, 2009
Aims: The extent to which hemostatic and inflammatory biomarkers are related to angina pectoris as compared with myocardial infarction (MI) remains uncertain.
Lennon, L, Lowe, GD, Rumley, A, Shaper, AG, Wannamethee, SG, Whincup, PH   +5 more
core   +1 more source

Blood clot inspired pore‐gradient nanofiber sponge with “outer filtration” and “inner adsorption” bifunction for rapid stop of uncontrolled hemorrhage

BMEMat, EarlyView.
In this study, by mimicking the nanofiber structure and netting blood cells function of fibrin network in blood clots, we developed a novel bioinspired quaternized chitosan nanofiber sponge with distinct blood cell filtration and blood plasma absorption bifunction for rapid hemostasis.
Fujin Zhou, Yong Yang, Yixuan Li, Ruolin Cao, Zheng Chen, Zhi Wang, Naiwen Tan, Lei Tian, Botao Song   +8 more
wiley   +1 more source

Targeting Raised von Willebrand Factor Levels in Liver Diseases: Opening Up Newer Therapeutic Avenues

European Medical Journal Hepatology, 2020
Raised levels of the blood coagulation protein von Willebrand factor (VWF) are now recognised to be important in patients with liver disease. The markedly raised plasma VWF levels in patients with acute liver failure and acute-on-chronic liver failure ...
Ashish Goel, Sukesh C. Nair, Uday Zachariah, Kunissery A. Balasubramanian, Ian Mackie, Elwyn Elias   +5 more
doaj   +1 more source

Enhanced Hemocompatibility via Bivalirudin and Bicarbonate as Alternative to Heparin in a Catheter‐Based Axial‐Flow System

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Cardiovascular therapeutic devices typically require systemic heparin due to underlying thrombotic risk. The Impella axial flow system further relies on internal perfusion with either a heparin‐containing or sodium bicarbonate purge solution during operation.
Kaitlyn R. Ammann, Christine E. Outridge, Tiana Silver, Sami Muslmani, Jun Ding, Vladimir Gilman, Scott Corbett, Marvin J. Slepian   +7 more
wiley   +1 more source

Human plasma-derived FVIII/VWD concentrate (Biostate): a review of experimental and clinical pharmacokinetic, efficacy and safety data

Drugs in Context, 2016
Human plasma-derived factor VIII/von Willebrand factor complex concentrates are used to control bleeding in patients with von Willebrand disease (VWD) or haemophilia A (HA).
Paul Harper, Emmanuel J Favaloro, Julie Curtin, Chris Barnes, Scott Dunkley   +4 more
doaj   +1 more source

Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: A new potential target for antifibrotic therapy [PDF]

, 2018
Background: Fibrosis may be considered the hallmark of systemic sclerosis (SSc), the end stage triggered by different pathological events. Transforming growth factor-β (TGF-β) and platelet-derived growth factor BB (PDGF-BB) are profibrotic molecules ...
Berardicurti O., Carubbi F., Ciccia F., Cipriani P., Di Bartolomeo S., Di Benedetto P., Giacomelli R., Guggino G., Liakouli V., Panzera N., Ruscitti P., Triolo G.   +11 more
core   +1 more source

Use of PopPK and E‐R Analyses toward Explaining Causal Link Between ADAMTS13 in Recombinant vs. Plasma‐Based Therapies and Clinical Effects in cTTP

Clinical Pharmacology &Therapeutics, EarlyView.
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, potentially life‐threatening condition caused by a deficiency of the blood enzyme ADAMTS13. Until now, ADAMTS13 replacement has been achieved with infusions of plasma or plasma‐based therapies (PBT).
Munjal Patel, Huijuan Xu, Olivier Barriere, Paul Diderichsen, Parth Patwari, Andy Z. X. Zhu, Jean François Marier, Thomas Peyret, Linda T. Wang, Björn Mellgård, Wenping Wang, Indranil Bhattacharya   +11 more
wiley   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Plasma Level of von Willebrand Factor Propeptide at Diagnosis: A Marker of Subsequent Renal Dysfunction in Autoimmune Rheumatic Diseases

Clinical and Applied Thrombosis/Hemostasis, 2020
Introduction: Patients with systemic autoimmune rheumatic diseases (SARDs) such as rheumatoid arthritis, systemic lupus erythematosus (SLE), Sjögren syndrome, and systemic sclerosis, which are chronic inflammatory diseases, are prone to develop renal ...
Noritaka Yada, Kiyomi Yoshimoto, Hiromasa Kawashima, Ryo Yoneima, Nobushiro Nishimura, Yoshiaki Tai, Emiko Tsushima, Makiko Miyamoto, Shiro Ono, Masanori Matsumoto, Takashi Fujimoto, Kenji Nishio   +11 more
doaj   +1 more source