Acquired von Willebrand Syndrome Associated with Cardiovascular Diseases
Journal of atherosclerosis and thrombosis, 2019 The blood glycoprotein von Willebrand factor (VWF) plays an important role in hemostasis and thrombosis. VWF is produced and secreted as large multimers by endothelial cells and megakaryocytes.
H. Horiuchi +4 more
semanticscholar +1 more source
Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure. [PDF]
, 2009 Decreased activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease, was recently reported in cardiovascular diseases and in hepatic failure.
Borgulya, Gábor +10 more
core +1 more source
mBio, 2020 Septic arthritis, one of the most dangerous joint diseases, is predominantly caused by Staphylococcus aureus. In contrast, coagulase-negative staphylococci are rarely found in septic arthritis. We hypothesize that coagulases released by S.
Manli Na +10 more
doaj +1 more source
The Role of ABO Blood Type in Thrombosis Scoring Systems [PDF]
, 2017 In addition to their major role in transfusion medicine, there is increasing evidence that ABO blood group antigens (complex carbohydrate molecules widely expressed on the surface of red blood cells and several other cell types) are implicated in the ...
Catalano, Liviana +5 more
core +1 more source
بررسی درصد فراوانی بیماری von Willebrand در زنان با خونریزی شدید قاعدگی
مجله دانشکده پزشکی اصفهان, 2018 مقدمه: شیوع بیماری von Willebrand در بیماران دارای خونریزی شدید قاعدگی، در مطالعات غیر بومی و بسته به جمعیت مورد مطالعه، بین 20-5 درصد برآورد شده است. شیوع این بیماری در ایران تنها در یک مطالعه بررسی شده است.
Fariborz Mokarian +4 more
doaj +1 more source
The Role of von Willebrand Factor in Vascular Inflammation: From Pathogenesis to Targeted Therapy
Mediators of Inflammation, 2017 Beyond its role in hemostasis, von Willebrand factor (VWF) is an emerging mediator of vascular inflammation. Recent studies highlight the involvement of VWF and its regulator, ADAMTS13, in mechanisms that underlie vascular inflammation and ...
F. Gragnano +14 more
semanticscholar +1 more source
Mechanobiology of shear-induced platelet aggregation leading to occlusive arterial thrombosis: a multiscale in silico analysis [PDF]
, 2021 Occlusive thrombosis in arteries causes heart attacks and strokes. The rapid growth of thrombus at elevated shear rates (~10,000 1/s) relies on shear-induced platelet aggregation (SIPA) thought to come about from the entanglement of von Willebrand factor (VWF) molecules.
arxiv +1 more source
Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]
, 2009 The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Bõze, Tamás +9 more
core +1 more source
Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura.
New England Journal of Medicine, 1998 BACKGROUND Thrombotic thrombocytopenic purpura is a potentially fatal disease characterized by widespread platelet thrombi in the microcirculation. In the normal circulation, von Willebrand factor is cleaved by a plasma protease.
H. Tsai, E. Lian
semanticscholar +1 more source
Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report
Caspian Journal of Neurological Sciences, 2022 Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system ...
Mohsen Farjoud Kouhanjani +2 more
doaj