Results 31 to 40 of about 55,967 (276)

Structure and Function of Recombinant versus Plasma-Derived von Willebrand Factor and Impact on Multimer Pharmacokinetics in von Willebrand Disease

Journal of Blood Medicine, 2022
Herbert Gritsch,1 Gerald Schrenk,1 Nina Weinhappl,1 Björn Mellgård,2 Bruce Ewenstein,2 Peter L Turecek3,4 1Pharmaceutical Sciences, Baxalta Innovations GmbH, a Takeda Company, Vienna, Austria; 2Rare Genetics and Hematology, Research & Development, Takeda
Gritsch H, Schrenk G, Weinhappl N, Mellgård B, Ewenstein B, Turecek PL   +5 more
doaj  

Correlation of intracardiac hemodynamics indicators with von Willebrand factor – Marker of endothelial dysfunction in patients with coronary artery disease combined with coronavirus disease (COVID-19) [PDF]

Българска кардиология
The research relevance is predefined by the need to establish the relationship and identify new markers and potential contributions to clinical practice and scientific progress.
V. Netiazhenko, S. Mostovyi, O. Safonova
doaj   +3 more sources

von Willebrand Disease

Medicine, 1997
Considerable progress has been made in characterizing the specific molecular defects responsible for the heterogeneous disorder known as von Willebrand disease (VWD). A large number of molecular defects have been identified and precise characterization may now be possible in the majority of type 2A, type 2B, type 2N, and potentially also type 3 VWD ...
W C, Nichols, D, Ginsburg
openaire   +2 more sources

Connexin 40 promoter-based enrichment of embryonic stem cell-derived cardiovascular progenitor cells [PDF]

, 2008
Background: Pluripotent embryonic stem (ES) cells that can differentiate into functional cardiomyocytes as well as vascular cells in cell culture may open the door to cardiovascular cell transplantation.
David, R., Franz, Wolfgang-M., Theiss, H.   +2 more
core   +1 more source

Platelet Biochemistry and Morphology after Cryopreservation [PDF]

, 2020
Platelet cryopreservation has been investigated for several decades as an alternative to room temperature storage of platelet concentrates. The use of dimethylsulfoxide as a cryoprotectant has improved platelet storage and cryopreserved concentrates can ...
Compernolle, Veerle, Feys, Hendrik, Six, Katrijn   +2 more
core   +1 more source

Global Overview of Von Willebrand Disease Research: A Bibliometric Study

Journal of Applied Hematology
INTRODUCTION: Von Willebrand disease (VWD) is a hereditary bleeding disorder with a high global prevalence. The aim of this study is to analyze the global landscape of scientific production on VWD.
John Barja-Ore, Brandon Emerson Guillen-Calle, Jhony Jesus Chafloque Chavesta, Zaida Zagaceta Guevara, Sandra Muñoz-Huaracán, Guipsy Rebolledo-Aburto   +5 more
doaj   +1 more source

Biomarkers of Clot Activation and Degradation and Risk of Future Major Cardiovascular Events in Acute Exacerbation of COPD: A Cohort Sub-Study in a Randomized Trial Population

Biomedicines, 2022
Cardiovascular diseases are common in patients with chronic obstructive pulmonary disease (COPD). Clot formation and resolution secondary to systemic inflammation may be a part of the explanation.
Peter Kamstrup, Jannie Marie Bülow Sand, Charlotte Suppli Ulrik, Julie Janner, Christian Philip Rønn, Sarah Rank Rønnow, Diana Julie Leeming, Sidse Graff Jensen, Torgny Wilcke, Alexander G. Mathioudakis, Marc Miravitlles, Therese Lapperre, Elisabeth Bendstrup, Ruth Frikke-Schmidt, Daniel D. Murray, Theis Itenov, Apostolos Bossios, Susanne Dam Nielsen, Jørgen Vestbo, Tor Biering-Sørensen, Morten Karsdal, Jens-Ulrik Jensen, Pradeesh Sivapalan   +22 more
doaj   +1 more source

Treatment of Von Willebrand Disease [PDF]

Thrombosis and Haemostasis, 1998
SummaryIn von Willebrand disease, there are two main options for the treatment of spontaneous bleeding episodes and for bleeding prophylaxis: desmopressin and transfusional therapy with plasma products. Desmopressin is the treatment of choice for most patients with type 1, who account for approximately 70 to 80 per cent of all cases with the disease ...
C. A. Lee, C. M. Kessler, D. Varon, U. Martinowitz, M. Heim, P. M. MANNUCCI   +5 more
openaire   +6 more sources

Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria [PDF]

, 2014
Systemic inflammation and sequestration of parasitized erythrocytes are central processes in the pathophysiology of severe Plasmodium falciparum childhood malaria. However, it is still not understood why some children are more at risks to develop malaria
Afolabi, Nathaniel K., Ajetunmobi, Wasiu A., Akinbami, Felix O., Akinkunmi, Francis, Bachmann, Julie, Brown, Biobele J., Burte, Florence, Conte, Ianina, Fernandez-Reyes, Delmiro, Kampf, Caroline, Nilsson, Peter, Omokhodion, Samuel, Orimadegun, Adebola E., Pawitan, Yudi, Pramana, Setia, Schwenk, Jochen M., Shokunbi, Wuraola A., Sodeinde, Olugbemiro, Uhlen, Mathias, Wahlgren, Mats   +19 more
core   +3 more sources

Acquired von Willebrand Syndrome Secondary to Normally Functioning Mechanical Aortic Valve and High-Output Cardiac State

Journal of Cardiovascular Development and Disease, 2022
Acquired von Willebrand syndrome (AVWS) is caused by an acquired deficiency of von Willebrand factor (VWF), a multimeric protein required for primary hemostasis. For patients with heart valve diseases, high gradient across the malfunctioning valves could
Xinglin Yang, Jinghong Zhang, Yamin Lai, Xuemin Yan, Xiaoxiao Guo, Jianhua Han, Jihai Liu, Jiangshan Wang, Huadong Zhu   +8 more
doaj   +1 more source