Results 31 to 40 of about 160,288 (338)

The Expression of von Willebrand Factor-Binding Protein Determines Joint-Invading Capacity of Staphylococcus aureus, a Core Mechanism of Septic Arthritis

open access: yesmBio, 2020
Septic arthritis, one of the most dangerous joint diseases, is predominantly caused by Staphylococcus aureus. In contrast, coagulase-negative staphylococci are rarely found in septic arthritis. We hypothesize that coagulases released by S.
Manli Na   +10 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

The Role of von Willebrand Factor in Vascular Inflammation: From Pathogenesis to Targeted Therapy

open access: yesMediators of Inflammation, 2017
Beyond its role in hemostasis, von Willebrand factor (VWF) is an emerging mediator of vascular inflammation. Recent studies highlight the involvement of VWF and its regulator, ADAMTS13, in mechanisms that underlie vascular inflammation and ...
F. Gragnano   +14 more
semanticscholar   +1 more source

High Glucose, But Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells [PDF]

open access: yes, 2015
Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases.
Aswin, S. (Soedjono)   +3 more
core   +2 more sources

Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura.

open access: yesNew England Journal of Medicine, 1998
BACKGROUND Thrombotic thrombocytopenic purpura is a potentially fatal disease characterized by widespread platelet thrombi in the microcirculation. In the normal circulation, von Willebrand factor is cleaved by a plasma protease.
H. Tsai, E. Lian
semanticscholar   +1 more source

Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report

open access: yesCaspian Journal of Neurological Sciences, 2022
Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system ...
Mohsen Farjoud Kouhanjani   +2 more
doaj  

بررسی درصد فراوانی بیماری von Willebrand در زنان با خونریزی شدید قاعدگی

open access: yesمجله دانشکده پزشکی اصفهان, 2018
مقدمه: شیوع بیماری von Willebrand در بیماران دارای خونریزی شدید قاعدگی، در مطالعات غیر بومی و بسته به جمعیت مورد مطالعه، بین 20-5 درصد برآورد شده است. شیوع این بیماری در ایران تنها در یک مطالعه بررسی شده است.
Fariborz Mokarian   +4 more
doaj   +1 more source

Comprehensive Analyses of Coagulation Parameters in Patients with Vascular Anomalies

open access: yesBiomolecules, 2022
Background: Vascular anomalies comprise a diverse group of rare diseases with altered blood flow and are often associated with coagulation disorders. The most common example is a localized intravascular coagulopathy in venous malformations leading to ...
Friedrich G. Kapp   +6 more
doaj   +1 more source

Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists [PDF]

open access: yes, 2014
Recent experimental evidence suggested that the synthetic peptide desmopressin (DDAVP) interferes tumor angiogenesis by inducing the formation of angiostatin.
Alonso, Daniel Fernando, Garona, Juan
core   +1 more source

von Willebrand factor propeptide: biology and clinical utility.

open access: yesBlood, 2015
von Willebrand factor (VWF) is a large multimeric glycoprotein that mediates the attachment of platelets to damaged endothelium and also serves as the carrier protein for coagulation factor VIII (FVIII), protecting it from proteolytic degradation ...
S. Haberichter
semanticscholar   +1 more source

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