Results 61 to 70 of about 192,512 (365)
Lower levels of vWF are associated with lower risk of cardiovascular disease
Objective The current study was undertaken to prospectively explore whether having low levels of von Willebrand factor (vWF) antigen and vWF activity reduce the risk for cardiovascular disease and death. Methods VWF antigen and vWF activity were measured
Pauline C. S. vanParidon+13 more
doaj +1 more source
A major function of platelets is keeping the vascular system intact. Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug.
Schattner, Mirta Ana
core +1 more source
Acquired von Willebrand disease (AvWD) represents a rare, potentially severe and most likely underdiagnosed category of hemorrhagic syndromes determined by quantitative, qualitative or functional, nonhereditary, alterations of von Willebrand factor (vWF)
Colită Andrei+6 more
doaj +1 more source
Connexin 40 promoter-based enrichment of embryonic stem cell-derived cardiovascular progenitor cells [PDF]
Background: Pluripotent embryonic stem (ES) cells that can differentiate into functional cardiomyocytes as well as vascular cells in cell culture may open the door to cardiovascular cell transplantation.
David, R.+2 more
core +1 more source
Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria [PDF]
Systemic inflammation and sequestration of parasitized erythrocytes are central processes in the pathophysiology of severe Plasmodium falciparum childhood malaria. However, it is still not understood why some children are more at risks to develop malaria
Afolabi, Nathaniel K.+19 more
core +3 more sources
Shear-induced unfolding and enzymatic cleavage of full-length VWF multimers [PDF]
Proteolysis of the multimeric blood coagulation protein von Willebrand Factor (VWF) by ADAMTS13 is crucial for prevention of microvascular thrombosis. ADAMTS13 cleaves VWF within the mechanosensitive A2 domain, which is believed to open under shear flow.
arxiv +1 more source
Q&A: Accessibility in Astronomy for the Visually Impaired [PDF]
We spoke with four researchers to understand the accessibility challenges in astronomy research, education and outreach for blind and visually impaired (BVI) persons, as well as solutions to these challenges and how it innovates data analysis methods for all astronomers.
arxiv +1 more source
Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]
<b>Background:</b> Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC ...
Atrih, A.+8 more
core +3 more sources
Mechanochemistry: Fundamental Principles and Applications
In this review, the physicochemical principles of mechanochemistry are first clarified. Based on this foundation, the research basis and cutting‐edge scientific achievements in four areas are introduced: solid‐state organic chemistry, polymers, interface science, and biomechanochemistry.
Liang Dong+4 more
wiley +1 more source
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang+4 more
wiley +1 more source