Results 191 to 200 of about 212,775 (379)

A Global Cross‐Sectional Database Study of Low Dose FVIII SHL Prophylaxis in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Haemophilia treatment is costly and only 25% of patients receive adequate care. Although not optimal, Factor VIII (FVIII) low‐dose prophylaxis (LDP) may reduce annual joint bleeding rates. Understanding FVIII usage, collected through the Web‐Accessible Population Pharmacokinetic Service–Hemophilia (WAPPS‐Hemo) platform, and its ...
Dagmar M. Hajducek, Oceana Sinkovic, Pierre Chelle, Alfonso Iorio, Andrea Edginton   +4 more
wiley   +1 more source

Burden of Haemophilia A in South Korea: A Serial Cross‐Sectional Study From 2008 to 2021

Haemophilia, EarlyView.
Abstract Background Overall use of factor VIII (FVIII) and prophylactic use have increased in South Korea over the past decade. However, there are no nationwide outcome data demonstrating its impact. This study aimed to identify patients with haemophilia A (PwHA) and observe trends in joint‐related outcomes and life‐threatening haemorrhages using ...
Sun‐Hong Kwon, Ji Kyoung Park, Hee Jo Baek, Jin Hyun Nam, Serim Min, Ae‐Ryeo Cho, Aeran Jung, Young‐Shil Park   +7 more
wiley   +1 more source

Von Willebrand factor in the vessel wall mediates platelet adherence [PDF]

, 1985
HV Stel, KS Sakariassen, PG de Groot, JA van Mourik, JJ Sixma   +4 more
openalex   +1 more source

Current Practice Regarding Bleeding Disorders of Unknown Cause in the Netherlands: A National Survey

Haemophilia, EarlyView.
ABSTRACT Introduction About 40%–70% of persons with a clinically relevant bleeding tendency who are referred to haemostasis experts are classified as having a ‘bleeding disorder of unknown cause’ (BDUC) as no biological entity can be found after extensive laboratory testing.
Caroline M. A. Mussert, Amaury L. L. Monard, Tirsa T. van Duijl, Yvonne M. C. Henskens, Maartje van den Biggelaar, Roger E. G. Schutgens, Saskia E. M. Schols, Karin J. Fijnvandraat, Karina Meijer, Paul L. den Exter, Laurens Nieuwenhuizen, Iris van Moort, Marieke J. H. A. Kruip, Marjon H. Cnossen, Floor C. J. I. Heubel‐Moenen, for the BDUC‐iN study group   +15 more
wiley   +1 more source

von Willebrand's disease characterized by increased ristocetin sensitivity and the presence of all von Willebrand factor multimers in plasma [PDF]

, 1986
Lars Holmberg, Erik Berntorp, Mikael Donnér, Nilsson Im   +3 more
openalex   +1 more source

Von Willebrand factor indicates bacterial translocation, inflammation, and procoagulant imbalance and predicts complications independently of portal hypertension severity

Alimentary Pharmacology and Therapeutics, 2018
M. Mandorfer, P. Schwabl, R. Paternostro, K. Pomej, D. Bauer, J. Thaler, Cihan Ay, P. Quehenberger, Monika Fritzer-Szekeres, Markus Peck-Radosavljevic, Michael Trauner, T. Reiberger, A. Ferlitsch   +12 more
semanticscholar   +1 more source

Switching From Standard to Extended Half‐Life Coagulation Factor Replacement in Haemophilia: Clinical Outcomes and Costs of Care in Finland

Haemophilia, EarlyView.
ABSTRACT Introduction Real‐world data are needed to evaluate treatment implementation, outcomes and costs of care in haemophilia patients switching prophylaxis from standard half‐life (SHL) to extended half‐life (EHL) clotting factor concentrates (CFCs).
Mirkka Koivusalo, Timea Szanto, Tuomas Kovalainen, Aino Vesikansa, Outi Laine, Anu Partanen, Timo Siitonen, Marko Vesanen, Juha Mehtälä, Nina Sarnesto, Johanna Haapkylä, Anna‐Elina Lehtinen, Riitta Lassila   +12 more
wiley   +1 more source

Platelet von Willebrand factor: evidence for its involvement in platelet adhesion to collagen [PDF]

, 1987
E Fressinaud, Dominique Baruch, C Rothschild, HR Baumgartner, Dominique Meyer   +4 more
openalex   +1 more source

Integrating Next‐Generation Sequencing Into Routine Molecular Diagnosis of Inherited Coagulation Factor Deficiencies: Real‐World Data From Spanish Patients

Haemophilia, EarlyView.
ABSTRACT Introduction Inherited coagulation factor deficiencies (ICFD) result from plasma protein deficiencies, impacting blood coagulation cascade and leading to haemorrhagic diathesis. Advancements in next‐generation sequencing (NGS) technology have enabled high‐throughput methods for molecular ICFD diagnosis.
Nina Borràs, Natàlia Comes, Lorena Ramírez, Rafael Parra, Carmen Altisent, Álvaro Lorenzo‐Vizcaya, Cristina Marzo‐Alonso, Maria‐Fernanda López‐Fernández, Mariana Canaro, María Falcón‐Rodríguez, Ángela Cortes‐Vidal, Mario A. Rios de Paz, José Antonio Rodríguez‐García, Ana Moreto‐Quintana, Perla Bandini, Carlos Hobeich, Irene Corrales, Francisco Vidal   +17 more
wiley   +1 more source

INVESTIGATION OF RISTOCETIN-INDUCED PLATELET AGGREGATION, PARAMETERS OF VON WILLEBRAND FACTOR AND THE COAGULATION FACTOR VIII AT ESSENTIAL ARTERIAL HYPERTENSION IN CHILDREN

Acta Biomedica Scientifica, 2014
Ristocetin-induced platelet aggregation, von Willebrand factor and coagulation factor VIII of 170 children with essential arterial hypertension and 40 healthy children were investigated.
M. V. Gomellya
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