Results 191 to 200 of about 109,978 (227)

DNA methylation is associated with von Willebrand factor and coagulation factor VIII plasma levels: the atherosclerosis risk in communities study

Julie Hahn, Jan Bressler, Myriam Fornage, Eric Boerwinkle, N L Smith, Alanna C. Morrison, Paul S. de Vries   +6 more
openalex   +1 more source

Determination of the Level of von Willebrand Factor, ADAMTS13, and Ratio of ADAMTS13:von Willebrand Factor in Sickle Cell Disease Patients.

Ann Afr Med
Onorhide AK, Idongesit AS, Olanrewaju OP.   +2 more
europepmc   +1 more source

Novel functions for von Willebrand factor.

Blood
Atiq F, O'Donnell JS.
europepmc   +1 more source

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von Willebrand disease and von Willebrand factor

Haemophilia, 2022
AbstractSummaryProgress in both basic and translational research into the molecular mechanisms of VWD can be seen in multiple fields.Genetics of VWDIn the past several decades, knowledge of the underlying pathogenesis of von Willebrand disease (VWD) has increased tremendously, thanks in no small part to detailed genetic mapping of the von Willebrand ...
Brooke, Sadler, Giancarlo, Castaman, James S, O'Donnell   +2 more
openaire   +2 more sources

von Willebrand factor

The FASEB Journal, 1993
von Willebrand factor is a multimeric glycoprotein essential for the normal arrest of bleeding after tissue injury (hemostasis). The molecule is present in blood, both in plasma and inside platelets, as well as in endothelial cells and the subendothelial matrix of the vessel wall. Through multiple functional domains, von Willebrand
Z M, Ruggeri, J, Ware
openaire   +2 more sources

The von Willebrand factor

La Ricerca in Clinica e in Laboratorio, 1990
Von Willebrand factor (vWf) is a multimeric and multivalent adhesive protein which is essential for platelet adhesion to subendothelium and for stabilization of factor VIII procoagulant activity in circulation. The quantitative measurement of vWf involves essentially two different approaches.
F, Rodeghiero, G, Castaman
openaire   +2 more sources

Platelet von Willebrand Factor

Mayo Clinic Proceedings, 1991
von Willebrand factor (vWF) circulates in the blood in two distinct compartments. One, plasma vWF, is synthesized and released from endothelial cells; the second, synthesized by megakaryocytes, circulates in platelets primarily stored in the alpha granules.
H R, Gralnick, S B, Williams, L P, McKeown, L, Magruder, K, Hansmann, M, Vail, R I, Parker   +6 more
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Platelet von Willebrand factor: Comparison with plasma von Willebrand factor

Thrombosis Research, 1985
Platelet von Willebrand factor (vWf) was compared to its plasma counterpart. The platelet vWf was different from plasma vWf in that the multimeric organization was different, larger multimers were present, and the ratio of vWf activity to antigen was higher.
H R, Gralnick, S B, Williams, L P, McKeown, D M, Krizek, B C, Shafer, M E, Rick   +5 more
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Von Willebrand factor and thrombosis

Annals of Hematology, 2006
There is increasing evidence that von Willebrand factor (VWF), an adhesive multimeric protein that has an important function in primary hemostasis and as a carrier of factor VIII, has a pivotal role in thrombogenesis. In fact, while the presence in plasma of unusually large VWF multimers due to a congenital or acquired deficiency of a VWF-cleaving ...
Franchini M, LIPPI, Giuseppe
openaire   +2 more sources