Proteolytic cleavage of human von Willebrand factor induced by enzyme(s) released from polymorphonuclear cells [PDF]
Thompson Ea, M. Hope Howard
openalex +1 more source
ABSTRACT Background Cyclic sex‐hormone fluctuation impacts clotting factor concentrations, being lowest during the follicular phase of the menstrual cycle. This pattern is unexplored in women with heavy menstrual bleeding (HMB), but potentially affects the timely diagnosis of underlying bleeding disorders.
Anne de Vaan+5 more
wiley +1 more source
Comparison of inhibitory and binding characteristics of an antibody causing acquired von Willebrand syndrome: an assay for von Willebrand factor binding by antibody [PDF]
WA Fricke+3 more
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von Willebrand factor and atherosclerosis [PDF]
openaire +4 more sources
Estimating the Factor VIII‐Equivalent Activity of Emicizumab Using Global Assays of Haemostasis
ABSTRACT Background Emicizumab is a bispecific monoclonal antibody mimicking factor (F) VIII activity and an effective therapy for prophylaxis in people with haemophilia A (PWHA). The FVIII‐equivalent activity (FVIIIeq) of emicizumab remains unknown. Objectives To estimate FVIIIeq of emicizumab using global assays of haemostasis.
Daniel Kraemmer+6 more
wiley +1 more source
DDAVP and epinephrine-induced changes in the localization of von Willebrand factor antigen in endothelial cells of human oral mucosa [PDF]
M Takeuchi, H Nagura, Teruo Kanéda
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Self‐assembly of short biopeptides onto skin tissue components studied using QCM‐D
An understanding of the interactions of the skin care products with skin tissue will enable rational design more effective products. We show the use of Quartz Crystal Microbalance with Dissipation (QCM‐D) to monitor in real time the adsorption behaviour of oligopeptides used in the cosmetic industry onto the components in skin tissue ...
N. Sanjeeva Murthy+3 more
wiley +1 more source
Sialic acid prevents loss of large von Willebrand factor multimers by protecting against amino-terminal proteolytic cleavage [PDF]
Scott D. Berkowitz, AB Federici
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ABSTRACT Introduction Light transmission platelet aggregometry (LTA) is useful to diagnose platelet function disorders (PFD). We evaluated the precision and reproducibility of LTA with low platelet count platelet‐rich plasma (LPRP). Methods LPRP maximal aggregation (MA) precision for informative agonists and LTA reproducibility were assessed using ...
Catherine P. M. Hayward+3 more
wiley +1 more source
In vivo interaction of von Willebrand factor with platelets following cryoprecipitate transfusion in platelet-type von Willebrand's disease [PDF]
JL Miller, BD Boselli, JM Kupinski
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