Results 201 to 210 of about 212,775 (379)

Clotting Factor Concentration During Menstrual Phases in Women With and Without Heavy Menstrual Bleeding: A Systematic Review and Meta‐Analysis

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Cyclic sex‐hormone fluctuation impacts clotting factor concentrations, being lowest during the follicular phase of the menstrual cycle. This pattern is unexplored in women with heavy menstrual bleeding (HMB), but potentially affects the timely diagnosis of underlying bleeding disorders.
Anne de Vaan   +5 more
wiley   +1 more source

Estimating the Factor VIII‐Equivalent Activity of Emicizumab Using Global Assays of Haemostasis

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Emicizumab is a bispecific monoclonal antibody mimicking factor (F) VIII activity and an effective therapy for prophylaxis in people with haemophilia A (PWHA). The FVIII‐equivalent activity (FVIIIeq) of emicizumab remains unknown. Objectives To estimate FVIIIeq of emicizumab using global assays of haemostasis.
Daniel Kraemmer   +6 more
wiley   +1 more source

Self‐assembly of short biopeptides onto skin tissue components studied using QCM‐D

open access: yesInternational Journal of Cosmetic Science, EarlyView.
An understanding of the interactions of the skin care products with skin tissue will enable rational design more effective products. We show the use of Quartz Crystal Microbalance with Dissipation (QCM‐D) to monitor in real time the adsorption behaviour of oligopeptides used in the cosmetic industry onto the components in skin tissue ...
N. Sanjeeva Murthy   +3 more
wiley   +1 more source

How Trustworthy is Light Transmittance Platelet Aggregometry With Low Platelet Count Samples? Insights From Test Replicates and Retrospective Analysis of Several Decades of Diagnostic Samples

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Light transmission platelet aggregometry (LTA) is useful to diagnose platelet function disorders (PFD). We evaluated the precision and reproducibility of LTA with low platelet count platelet‐rich plasma (LPRP). Methods LPRP maximal aggregation (MA) precision for informative agonists and LTA reproducibility were assessed using ...
Catherine P. M. Hayward   +3 more
wiley   +1 more source

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